Senior Director, Medical Affairs

Editas Medicine; Cambridge (MA); On-site; USD 280,000 - 325,000; Full time

Benefits offered by this job

Health insurance

HSA

Dental & Vision insurance

401(k) with match

Tuition reimbursement

Wellness programs

Paid time off

Job summary

Editas Medicine in Cambridge, MA seeks a Senior Director of Medical Affairs to lead strategic planning and execution from early clinical development through lifecycle management for EDIT-401, a potential one-time therapy addressing LDL cholesterol. You will shape medical strategy, engage with KOLs, and drive external collaborations.

The role requires a PhD/MD/PharmD and 10+ years in biopharma Medical Affairs or scientific communications, with a track record of compliance and impactful project

Qualifications

• Advanced health/life sciences degree (PhD, PharmD, or MD).
• 10+ years in biopharma Medical Affairs or Scientific Communications.
• Proven record of compliance with regulatory, legal, and operational rules.
• Experience with one-time curative therapies and early clinical development.
• Demonstrated ability to build relationships with KOLs and patient advocacy groups.
• Excellent written and oral communication with senior leadership and cross-functional partners.
• Ability to analyze complex scientific data and translate into medical strategy.
• Track record of planning and delivering high-impact projects on time.

Responsibilities

• Lead medical and scientific strategic planning and operational execution from early-clinical through lifecycle management for lead in vivo development candidate EDIT-401.
• Develop and lead Medical Affairs strategies including medical communications, engagement with opinion leaders, data dissemination, and external collaborations.
• Establish strategic publication and congress plans; craft key messages on unmet need, MOA, and target product profile.
• Build core scientific platforms, disease-state education materials, and standard medical response documents with Clinical Development, Regulatory, Research, and Legal teams.
• Serve as internal medical-scientific expert, translating data into actionable medical strategy across trials and real-world evidence.
• Cultivate and maintain trusted relationships with the medical community through thought leaders, investigators, steering committees, and medical societies.
• Design and lead scientific advisory boards to gather insights on trial designs and lifecycle planning.
• Partner with Clinical Operations and Clinical Development to input in design and execution of trials and enrollment.
• Engage with patient advocacy organizations to build trust and awareness.
• Direct external medical communication agencies, manage budgets, and mentor internal teams.

Skills

Medical Affairs leadership

Scientific communications

Stakeholder engagement

Regulatory compliance

Data interpretation

Education

PhD/PharmD/MD

Job description

At Editas Medicine, we are pioneeringthe possible. Our mission and commitmentisto translate the power and potential of the CRISPR/Cas12a and CRISPR/Cas9 genome editing systems into a robust pipeline of medicines for people living with serious diseases around the world.Our goal is to discover, develop, manufacture, and commercialize transformative, durable, precision genomic medicines for a broad class of diseases.

Why Choose Editas?

At Editas Medicine,we’rea team of passionate problem solvers, harnessing the power and potential of CRISPR gene editing to transform the future of medicine. Driven by a shared purpose to serve people living with serious diseases, we succeed together through collaboration, mutual respect, and innovation. If you want to be part of a team where your voice is heard and respected, where you can operate at the forefront of gene editing, and push the boundaries of what’s possible in medicine, come join us and become an Editor!

Decoding The Role:

The primary focus of this role is tolead medical and scientific strategic planning and operational execution ofcore medical affairs activities from early-clinical pha se through lifecycle management forour leadin vivodevelopment candidate, EDIT-401, a potential best-in-class, one-time therapy designed to significantly reduce LDL cholesterol levels.This rolewillbuild Medical Affairs capabilities whileproviding scientific leadership and strategic direction across cross-functional teamsand strong engagement with external stakeholders.

As theSenior Director,Medical Affairsyou will:

• Develop and lead Medical Affairs strategies including medical communications, engagement with opinion leaders, data dissemination, and external collaborations

• Establish and execute a strategic publicationand congress plan; work with internal colleagues to develop key messages on unmet need, mechanism of action, and target product profile

• Build core scientific platforms, disease-state education materials, and standard medical response documents working closely with Clinical Development, Regulatory, Research, and Legal to develop a consistent, compliant scientific narrative

• Serve as internal medical-scientific expert, providing scientific interpretation of data (clinical trials, real-world evidence, published literature) and translating insights into actionable medical strategy

• Cultivate andmaintaintrusted relationships with the medical community by driving scientific exchange with thought leaders, investigators, steering committees, and medical societies.

• Design and lead scientific advisory boards to gather insights on clinical trial designs, patient selection criteria, target productprofileand lifecycle planning

• Partner with Clinical Operations and Clinical Development to provide input in design and execution of clinical trial programs andfacilitateenrollment of company sponsored clinical trials

• Engage with patient advocacy organizations to build trust and awareness within the community

• Direct external medical communication agencies, manage operational budgets, and mentor internal team members

The Ideal Transcript:

To thrive in this role,you’llneed:

• Advanced health/life sciences degree (PhD, PharmD, or MD)

• 10+ years in biopharma Medical Affairs or Scientific Communications, experience with one-time curative intent therapies and early clinical phase development preferred

• Successful record of achieving andmaintainingcompliance with all applicable regulatory, legal, and operational rules

• Demonstratedexperiencebuildingproductive relationships with internal stakeholders and external stakeholders including KOLs and patient advocacy groups

• Excellent written and oral communication skills with the ability to influence senior leadership, cross-functional partners, and external stakeholders.

• Capacity to critically analyze and interpret complex scientific data and translate it into medical strategy

• Track recordof planning, initiating, and completing high-impact projects within established timelines.

• History of thriving in ambiguity, managing multiple priorities whilemaintainingfocus on achieving defined objectives

Editas provides a comprehensive array of benefits to all employees, including a Blue Cross Blue Shield PPO Medical Plan, a company-funded Health Savings Account, Dental and Vision Insurance, Life and Disability Insurance, Dependent Care Account, Tuition Reimbursement, 401(k) plan with company match, Employee Assistance Plan, Wellness Programs, and a flexible Paid Time Off policy.

Salary Range:

$280,000 -$325,000

Pay Transparency

Editas Medicine is committed to transparency and accuracy in our hiring practices. Theanticipatedsalary range for each position is posted within the role. The final salary offer will bedeterminedbased on a comprehensive assessment of the candidate's qualifications, including education, training, and relevant experience.Additionalfactors such as external market conditions, the role's criticality, and internal equity will also be considered.Editas Medicine's compensation philosophy ensures fair and equitable pay practices.