Senior Director, Epidemiology

Biopharma Careers; West Point (MS); On-site; USD 191,000 - 300,000; Full time

Benefits offered by this job

Salary range transparency

Job summary

Merck is seeking a Senior Director of Epidemiology to lead a team focusing on Respiratory Disease and Hospital Specialty Medicine areas. You will set epidemiology strategy, guide data collection, and oversee study designs while coordinating with regulatory, safety, and clinical teams to support product development and post-approval activities.

The role requires a PhD in Epidemiology with extensive experience, strong leadership, and excellent communication. Travel about 5% is expected.

Qualifications

• Required: PhD in Epidemiology with 8 or more years of relevant work experience.
• Preferred: PhD in Epidemiology (or related field) or MD degree with additional research training in Epidemiology.

Responsibilities

• Lead management and scientific oversight of a team of epidemiologists focusing on Respiratory Disease and Hospital Specialty Medicine therapeutic areas.
• Set program-wide epidemiology/RWE strategy and align with regulatory and HTA requirements.
• Address cross-functional issues (study execution, resourcing, budgets) and ensure timely, within-budget deliverables.
• Mentor team members, recruit, allocate resources, and supervise performance.
• Publish and present to enhance external scientific reputation and collaborate with external partners.

Skills

Clinical Development

Data Access

Data Management

Epidemiology

Mentorship

Methods and Tools

Natural History

Organizational Performance Management

Regulatory Affairs Compliance

Regulatory Requirements

Researching

Stakeholder Relationship Management

Strategic Planning

Technical Advice

Education

PhD in Epidemiology

MD with Epidemiology training

Job description

Job Description

Under the general direction of the Associate Vice President in Vaccine/Infectious Disease (VID), Epidemiology, the Senior Director, Epidemiology has lead management and oversight responsibility for epidemiologic activities conducted by epidemiologists of their team on assigned products of our Company/indications and provides broad leadership and direction on scientific and operational aspects of epidemiologic research. The primary focus of this position is VID.

Key responsibilities

1. Has overall responsibility for management and scientific oversight of a team of epidemiologists focusing on Respiratory Disease, as well as Hospital Specialty Medicine therapeutic areas (TAs). In specific:
   Makes key epidemiologic decisions and is accountable for deliverables (strategies, plans, timelines, and reports) and for study budgets for the team.
   Solves operational and cross-functional issues (study execution, resourcing, personnel matters, cross-divisional coordination) and ensure deliverables are completed on schedule and within budget.
   Provides expert advice and guidance on the scientific and operational aspects of primary sample and data collection/natural history studies that are unique in Vaccine/Infectious Disease TA to support the clinical programs.
   Leads people management responsibilities: recruit, assign projects, allocate resources, conduct performance management, approve expenses, and provide coaching, mentoring, and professional development for epidemiology staff.
   Maintains and enhances the group’s external scientific reputation by publishing, presenting at conferences, peer-reviewing journals, and participating in academic or consortia activities (teaching, supervising trainees) as appropriate.
2. Provides guidance to team members on the overall program-wide epidemiology/real world evidence (RWE) strategy and ensure that the strategy aligns with the program’s clinical, regulatory and HTA strategies. The responsibilities include, but not limited to the following:
   Sets epidemiology strategy at the product/indication level, aligning Epidemiology strategy plans and safety/effectiveness evaluations with overall therapeutic area strategy and regulatory requirements.
   Reviews regulatory documents, reports, and scientific publications for assigned TAs to ensure accuracy, consistency, and alignment with company strategy and regulatory expectations.
   Provides expert scientific and regulatory guidance during product development and post-approval phases, including interpreting results, advising on regulatory submissions and responses, and participating in meetings with regulatory agencies, external scientific or industry consortia as needed.
   Track records of identifying opportunities and proposing innovative/advanced methodology to leverage RWE to support clinical development and regulatory decisions.
3. Proven ability to build strong, productive relationships with counterparts across clinical development, safety/pharmacovigilance, regulatory affairs, outcomes research, medical affairs, commercial, and external partners. Actively socializes epidemiologic strategies and insights, secures stakeholder buy-in for study design and evidence generation, and leverages these partnerships to expand the team’s influence, resources, and impact across programs. Specifically:
   Translate epidemiology needs into business terms to obtain resourcing, data access, and operational support from partner functions.
   Identify and cultivate executive sponsors and key opinion leaders network to champion epidemiology initiatives and facilitate escalation when needed.
   Share study findings and methodological rationale in stakeholder forums to anticipate concerns and secure consensus before key decision points.
   Mentor team members on stakeholder management best practices and involve them in cross‑functional meetings to build internal credibility.

Education Minimum Requirement

Required: PhD in Epidemiology with 8 or more years of relevant work experience.
Preferred: PhD in Epidemiology (or related field) or MD degree with additional research training in Epidemiology.

Required Experience and Skills

Minimum of 8 years of relevant work experience preferably in the pharmaceutical or biotech industry.
People management experience.
Extensive experience in the successful direction of large epidemiologic projects; broad knowledge and experience in the application of epidemiologic approaches to problems in the Pharmaceutical or Biotechnology industry; and record of research publications in peer-reviewed journals.
Molecular epidemiology training/background.
Creative problem-solving ability and excellent communication skills (oral and written).
5% Travel.

Preferred Experience and Skills

Experiences in designing and conducting relevant epidemiologic biomarkers/natural history studies and activities.
Expertise and experiences using innovative/advanced methods to generate RWE supporting clinical development and regulatory decisions.
BARDS2020.

Additional Skills

Required Skills: Clinical Development, Data Access, Data Management, Epidemiology, Medical Affairs, Mentorship, Methods and Tools, Natural History, Organizational Performance Management, Pharmacovigilance, Publishing, Regulatory Affairs Compliance, Regulatory Requirements, Researching, Stakeholder Relationship Management, Strategic Planning, Technical Advice.

US and Puerto Rico Residents Only

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. We provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit EEOC Know Your Rights EEOC GINA Supplement.

We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.

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Salary Range

$190,800.00 - $300,300.00

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee’s position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

Benefits

We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits.