Senior Director / Director, Global Medical Affairs (Evidence Generation)

Scholar Rock Holding Corporation; Cambridge (MA); In loco; USD 150.000 - 210.000; Tempo pieno

Descrizione del lavoro

Scholar Rock Holding Corporation is seeking a leader in evidence generation to drive global strategies that demonstrate product value for neuromuscular indications. The role oversees design and execution of studies, real-world evidence, PRO research, and post-hoc analyses, ensuring regulatory and ethical compliance while collaborating with commercial and research teams.

You will partner with external experts, manage resources and vendors, and mentor Medical Affairs teams to advance publication

Competenze

• MD/PhD/PharmD or equivalent advanced degree in life sciences.
• 3–5 years in Evidence Generation or related field for Director level, or 6–8+ years for Senior Director level.
• Proven track record delivering cross-functional programs with measurable results.

Mansioni

• Lead the development and execution of global evidence generation strategies to support product value demonstration and lifecycle management.
• Direct design and oversight of medical affairs-led evidence generation initiatives with adherence to regulatory and quality standards.
• Collaborate with cross-functional teams to integrate evidence generation into commercial evaluations and portfolio decisions.
• Engage external experts and key opinion leaders to inform study design and dissemination.
• Partner with Medical Communications to publish and disseminate findings and advance scientific impact.
• Develop and mentor global and regional Medical Affairs teams in evidence generation methodologies.
• Oversee budgets, CROs/vendors, and resources to deliver on KPIs while maintaining compliance.

Conoscenze

Strategic leadership

Evidence generation

Real-world evidence

Cross-functional collaboration

KOL engagement

Communication

Formazione

MD/PhD/PharmD

Strumenti

Clinical trial design

Descrizione del lavoro

Scholar Rock is delivering muscle-targeted breakthroughs to transform the treatment of spinal muscular atrophy (SMA) and other rare neuromuscular diseases where muscle atrophy remains a critical unmet need.

As a global leader in myostatin biology, a field focused on proteins that regulate muscle mass, the biopharmaceutical company is named for the visual resemblance of a scholar rock to protein structures. Our commitment to unlock fundamentally different treatment approaches is powered by broad application of a proprietary platform, which has developed novel monoclonal antibodies to modulate protein growth factors with extraordinary selectivity. Scholar Rock works every day to create new possibilities for patients through its highly innovative anti-myostatin program, including opportunities in additional rare neuromuscular diseases. Learn more about our neuromuscular franchise at ScholarRock.com and follow @ScholarRock on X and on LinkedIn.

Summary of Position:

Position Responsibilities

• Strategic Leadership: Lead the development and execution of global evidence generation strategies that support product value demonstration, reimbursement, market access, and lifecycle management.


• Study Design & Oversight: Direct the design, implementation, and operational oversight of medical affairs-led evidence generation initiatives, ensuring all protocols are executed in strict compliance with global regulatory, ethical, and corporate quality standards. Core modalities include:
  
  
  • Prospective and retrospective observational studies
  
  
  • Real-world evidence (RWE) studies and database analyses
  
  
  • Patient-reported outcome (PRO) research
  
  
  • Qualitative and quantitative primary research
  
  
  • Phase IV studies and post-hoc analyses
  
  


• Cross-Functional Collaboration: Partner strategically with cross-functional teams to integrate evidence generation strategies into commercial evaluations and portfolio management decisions, successfully demonstrating product value to achieve global market access.


• External Stakeholder Engagement: Establish and maintain robust relationships with external experts, including key opinion leaders (KOLs), clinical researchers, and healthcare decision-makers, to accurately inform evidence needs and study designs.


• Scientific Dissemination: Partner with Medical Communications to develop publication and dissemination strategies that maximize the impact, scientific rigor, and visibility of evidence generation findings.


• Team Development: Support the development and training of global and regional Medical Affairs teams on evidence generation strategies, methodologies, and key study results.


• Project & Resource Management: Efficiently manage multiple evidence generation projects, key performance indicators (KPIs), and associated resources simultaneously, including budgets, CROs/vendors, and external collaborations.


• Culture Driver: Foster a culture of scientific rigor, innovation, compliance, collaboration, and patient focus across all evidence generation activities.

Candidate Requirements

• Education: MD, PhD, or PharmD or equivalent advanced degree in a relevant life sciences discipline.


• Experience & Track Record:
  
  
  • Director level: Minimum 3–5 years of experience in Evidence Generation, Real-World Evidence, Outcomes Research, or related functions within the pharmaceutical, biotechnology, or life science industry.
  
  
  • Senior Director level: Minimum 6–8+ years of experience in the tracking, design, and executive delivery of complex global evidence generation strategies within the biopharmaceutical industry.
  
  
  • Documented track record of delivering measurable project results and cross-functional success.
  
  


• Core Competencies: Strong written and verbal communication skills, exceptional interpersonal capabilities, and proven experience managing external vendor relationships.


• Therapeutic Area: Prior experience in neuromuscular diseases and/or rare diseases is highly preferred but not required.


• Travel: Ability to travel domestically and internationally (~15%).

Scholar Rock is an Equal Opportunity Employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.