Senior Director, Clinical Research, Atherosclerosis

MSD Malaysia; Rahway (NJ); Hybrid; USD 173,000 - 273,000; Full time

Benefits offered by this job

Medical, dental and vision benefits

401(k) retirement plan

Paid holidays

Vacation and sick days

Company-wide wellness programs

Job summary

Merck is seeking a Senior Director in the Atherosclerosis & Metabolism area to lead late-stage clinical development for investigational and marketed therapies. You will design trials, coordinate cross-functional teams, and guide regulatory reporting and publications.

The role requires MD-level qualification with a track record in industry or academia, and a strong capability to oversee multiple trials, mentor teams, and drive strategic development decisions across the full development cycle.

Qualifications

• M.D. or M.D./Ph.D. required.
• Industry or senior academic experience preferred.
• Minimum 3 years in clinical medicine.
• 3–5 years in drug development or biomedical research.
• Proven oversight of Phase 2/3 studies and protocols.
• Strong scholarly record and biomedical research background.
• Excellent interpersonal, teamwork, and communication skills.

Responsibilities

• Plan and direct late-stage clinical development for atherosclerosis drugs.
• Monitor ongoing trials and manage development strategies.
• Analyze clinical findings to support safety/efficacy decisions and regulatory documents.
• Collaborate with cross-functional teams and external partners.
• Develop development plans from preclinical to post-licensure; support BD assessments.

Skills

Atherosclerosis

Cardiovascular Diseases

Clinical Development

Clinical Research

Clinical Trials

Cross-Functional Teamwork

Drug Development

Medical Monitoring

Scientific Writing

Education

M.D. or M.D./Ph.D.

Job description

The Senior Director (Sr. Principal Scientist) has primary responsibility for the planning and directing clinical research activities involving new or marketed medicines in the Atherosclerosis section of the Atherosclerosis & Metabolism therapeutic area. Our company's Atherosclerosis & Metaboslim medicines span all phases of clinical development (pre-clinical to post-licensure). The Senior Director will manage the entire cycle of late-stage clinical development and studies, including development strategy, study design, initiation, execution, monitoring, analysis, regulatory reporting, and publication.

The Senior Director May Be Responsible For:

• Planning clinical trials (design, operational plans, settings) based on these clinical development strategies
• Monitoring and managing the conduct of ongoing or new clinical trials for investigational or marketed Atherosclerosis drugs
• Analyzing and summarizing the clinical findings from studies to support decisions regarding safety and efficacy as well as new drug applications, clinical study reports, or publication
• Participation in internal and joint internal/external research project teams relevant to the development of new compounds, and the further study of marketed compounds.
• Evaluating pre-clinical and translational work for the purpose of generating early clinical development plans and Investigational New Drug applications
• Developing clinical development strategies for investigational or marketed Atherosclerosis drugs
• Support of business development assessments of external opportunities

The Senior Director May:

• Work closely with the Clinical Scientists in the execution of clinical studies.
• Work closely with a cross-functional group of experts in commercialization, regulatory affairs, statistics, and manufacturing to manage clinical development projects; and assist the Executive Director and/or Associate Vice President in ensuring that appropriate Corporate personnel are informed of the progress of studies of our company and competitors' drugs, and of internal and external expert opinion on scientific questions relevant to their areas of responsibility.

Maintaining a strong scientific fund of knowledge by:

• Maintaining awareness of scientific developments within their area of expertise, in terms of new scientific findings, research methodologies
• Identifying scientifically and operationally strong investigators who can assist in the development of our company's investigational and marketed drugs
• Establishing communications with prominent clinical investigators in their particular field of interest, particularly those who will be willing and able to assist in the evaluation of our company's drugs
• Attending appropriate scientific meetings to maintain their competency and to maintain awareness of research activities in their area of responsibility.

To accomplish these goals, the Senior Director may: Author detailed development documents, presentations, budgets, and position papers for internal and external audiences Facilitate collaborations with external researchers around the world Travel on company business about twenty (20) percent of the time to manage future or ongoing clinical research projects.

Qualifications

• M.D or M.D./Ph.D. Required
• Must have experience in industry or as senior faculty in academia
• Minimum of 3 years experience in clinical medicine
• Minimum of 3-5 year of industry experience in drug development or biomedical research experience in academia
• Demonstrated success in overseeing Phase 2 and 3 clinical studies and protocols
• Demonstrated record of scientific scholarship and achievement
• Proven track record in clinical medicine and background in biomedical research
• Strong interpersonal skills, as well as the ability to function in a team environment
• Outstanding verbal and written communication and presentation skills

Preferred

• Board Certified or Eligible in Cardiology (adult or pediatric), Endocrinology, or Nephrology or related discipline Prior specific experience in clinical research and prior publication

Required Skills

• Atherosclerosis, Cardiovascular Diseases, Clinical Development, Clinical Research, Clinical Sciences, Clinical Trials, Cross-Functional Teamwork, Drug Development, Medical Monitoring, Scientific Writing

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process. As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit: EEOC Know Your Rights EEOC GINA Supplement We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively. Learn more about your rights, including under California, Colorado and other US State Acts

San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

Los Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance

The salary range for this role is $173,200.00 - $272,600.00 This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee’s position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs. The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits.

• medical
• dental
• vision healthcare and other insurance benefits (for employee and family)
• retirement benefits, including 401(k)
• paid holidays
• vacation
• compassionate and sick days

Employee Status: Regular
Relocation: No relocation
VISA Sponsorship: No
Travel Requirements: 25%
Flexible Work Arrangements: Hybrid
Shift: Not Indicated
Valid Driving License: No
Hazardous Material(s): n/a

Our company is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. The difference between potential and achievement lies in the spark that fuels innovation and inventiveness; this is the space where we have codified our legacy for over a century. Our success is backed by ethical integrity, forward momentum, and an inspiring mission to achieve new milestones in global healthcare.