Senior Director, Clinical Operations

Revolution Medicines; Redwood City (CA); Presencial; USD 244.000 - 305.000; Jornada completa

Ventajas ofrecidas por este puesto de trabajo

Equity awards

Learning and development opportunities

Robust benefits

Descripción de la vacante

Revolution Medicines seeks a Senior Director of Clinical Operations to own the operational design and execution of early-stage clinical studies. You will develop the Clinical Development Plan, manage trials globally, and lead Clinical Operations staff across projects while ensuring ICH/GCP compliance.

The role requires a strong track record in oncology trial leadership, CRO selection, and cross-functional collaboration within a fast-paced environment.

Formación

• BS/MS Degree in a scientific discipline with a minimum of 12 years of clinical operations experience in the pharmaceutical or biotech industry.
• 7+ years of project and line management experience.
• Extensive experience leading global phase 1-3 clinical trials within timelines, resources, and budgets.
• Experience with cooperative group studies and investigator sponsored trials preferred.
• Strong leadership and teamwork track record.
• Experience selecting CROs/vendors and managing external resources.
• Working knowledge of data management, data review and analysis, and pharmacovigilance.

Responsabilidades

• Develop, manage, and execute the Clinical Development Plan (CDP) with timelines, budgets, and resources.
• Oversee execution of clinical trials, including CRO/site selection.
• Deploy Clinical Operations staff and define roles for growth.
• Line management including hiring, performance, and mentorship.
• Collaborate with Clinical Development, Regulatory, QA, Finance, Legal to meet ICH/GCP guidelines.

Conocimientos

Leadership

Project management

CRO/vendor management

Data management

FDA/ICH/GCP knowledge

Communication

Educación

BS/MS in a scientific discipline

Herramientas

CTMS

EDC

Pharmacovigilance

Descripción del empleo

Revolution Medicines is a global, commercial-state oncology company dedicated to discovering, developing and delivering innovative medicines for patients with RAS-addicted cancers. Leveraging its differentiated RAS(ON) tri-complex inhibitor platform, the company is advancing a broad, integrated portfolio of oral RAS(ON) inhibitors designed to directly target the active, cancer-driving state of RAS.Founded on rigorous scientific inquiry and a willingness to challenge long-held assumptions, Revolution Medicines is committed to changing the trajectory of disease for patients with RAS-addicted cancers worldwide.

Our people are united by a shared way of working: follow the science, challenge assumptions, act with urgency and hold ourselves to a high standard of rigor—all in service of patients.

The Opportunity:

This is a unique opportunity for the right individual who has innate leadership and organizational skills, technical expertise in clinical oncology drug development in an industry setting, and experience in organizing and running clinical trials. As the Senior Director of Clinical Operations, you will be responsible for the operational design and structure of, and accountable for the execution of, Revolution Medicines early-stage clinical studies. Specifically, you will be responsible for:

• The development, management, and execution of the Clinical Development Plan (CDP) for clinical programs which includes clinical trial timeline estimates, budgets, and resource requirements.
• Oversight over the execution of clinical trials, including CRO selection and site selection.
• Successful planning and deployment of Clinical Operations staff for project and non-project related tasks. Establish clear roles and responsibilities for team members and include opportunities to stretch skills and enable growth.
• Line management responsibilities include hiring, performance management, career development and mentorship.
• Participate in or lead team meetings and collaborate with other functional groups within the company (e.g., Clinical Development, DMPK, Regulatory, QA, Finance, Legal, etc.) to achieve clinical study goals regulations and International Council for Harmonization (ICH)/ GCP guideline.

Required Skills, Experience and Education:

• BS/MS Degree in a scientific discipline with a minimum of 12 years of clinical operations experience in the pharmaceutical or biotech industry.
• Minimum of 7 years project and line management experience.
• Extensive experience in leading and managing global phase 1-3 clinical trials within designated timelines, resources, and budgets.
• Experience in working with cooperative group studies and investigator sponsored trials, preferred.
• A demonstrable record of strong leadership and teamwork.
• Extensive experience in selection of CROs/ vendors and management of external resources
• Must have a working knowledge of data management, data review and analysis, and drug safety, pharmacovigilance and other related functions as related to clinical trial conduct.
• Strong working knowledge of FDA Regulations, ICH Guidelines and GCPs governing the conduct of clinical trials.
• Thrives in a collaborative team setting and is driven by a desire to deploy innovative approaches and technologies in a high-energy environment.
• Thrives in a collaborative team setting and is driven by a desire to deploy innovative approaches and technologies in a high energy environment.
• Excellent written and verbal communication skills.
• Ability to act as an excellent ambassador for Revolution Medicines in interactions with key opinion leaders, scientific advisors, corporate partners and, where necessary, investors.
• Demonstrated ability to multi-task, prioritize options, anticipate challenges, and execute on goals as a member of an interdisciplinary team is extremely important.

Preferred Skills:

• Experience in oncology clinical trials.

The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.

Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.

Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.

Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact [e-mail].

Base Pay Salary Range

$244,000—$305,000 USD