Senior CRA- Oncology- Myelofibrosis

ICON Strategic Solutions; California (MO); On-site; USD 90,000 - 120,000; Full time

Benefits offered by this job

Competitive base salary

Health and wellbeing programmes

Retirement and pension plans

Life assurance

Employee assistance programmes

Job summary

ICON Strategic Solutions seeks a Senior Clinical Research Associate - Oncology (Myelofibrosis) for the West Region. You will serve as the primary point of contact between investigational sites and the sponsor, conduct all site visits, ensure ICH-GCP compliance, maintain CTMS/eTMF documentation, and support training and data quality.

Candidates should have a life sciences degree or RN, 3+ years on-site monitoring in pharma/CRO, oncology Myelofibrosis experience, and be able to travel up to 50%

Qualifications

• Bachelor’s degree in Life Sciences or RN, eligible to work in the United States without visa sponsorship.
• 3+ years of on-site monitoring experience in the pharmaceutical or CRO industry.
• Experience monitoring Oncology, specifically Myelofibrosis trials.
• Proficient in ICH-GCP, local regulatory requirements, and clinical systems like CTMS and eTMF.
• A clear communicator, problem-solver, and collaborative team player.
• Willing to travel up to 50% for on-site monitoring visits across the West region; preference for candidates near HUB airports.

Responsibilities

• Serve as the primary point of contact between investigational sites and the sponsor.
• Conduct site visits including selection, initiation, routine monitoring, and close-out.
• Ensure site compliance with ICH-GCP, SOPs, and regulations.
• Maintain up-to-date documentation in CTMS and eTMF systems.
• Support and track site staff training and maintain compliance records.
• Monitor patient safety with timely AE/SAE/PQC reporting.
• Support subject recruitment and retention at the site level.
• Oversee drug accountability, storage, return, or destruction.
• Resolve data queries and ensure high-quality data entry.
• Document site progress and escalate risks to the clinical team.
• Assist in tracking site budgets and payments; collaborate with CTAs, LTMs, and CTMs.

Skills

On-site monitoring

ICH-GCP familiarity

Travel availability

Communication

Collaboration

Problem solving

Education

Bachelor’s degree in Life Sciences or RN

Tools

CTMS

eTMF

Job description

At ICON Strategic Solutions, you will work in a sponsor-dedicated model, supported by ICON’s global expertise. As the world’s largest FSP organisation, with over 90 sponsor partnerships, we offer stability, career development and a collaborative environment where your work contributes to the development of treatments that benefit patients worldwide.

Senior Clinical Research Associate - Oncology (Myelofibrosis) - West Region

ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster.

As a values-driven organisation, integrity, collaboration, agility, and inclusion are at the heart of how we work and interact with each other, customers, patients and suppliers.

What You Will Be Doing:

• Serve as the primary point of contact between investigational sites and the sponsor
• Conduct all types of site visits, including selection, initiation, routine monitoring, and close-out
• Ensure site compliance with ICH-GCP, SOPs, and regulations
• Maintain up-to-date documentation in CTMS and eTMF systems
• Support and track site staff training and maintain compliance records
• Monitor patient safety, ensuring timely and accurate AE/SAE/PQC reporting
• Support subject recruitment and retention efforts at the site level
• Oversee drug accountability and ensure proper storage, return, or destruction
• Resolve data queries and drive timely, high-quality data entry
• Document site progress and elevate risks or issues to the clinical team
• Assist in tracking site budgets and ensuring timely site payments (as applicable)
• Collaborate with cross-functional partners including CTAs, LTMs, and CTMs

You are:

• A graduate with a Bachelor’s degree in Life Sciences or equivalent, or a qualified RN
• Eligible to work in United States without visa sponsorship
• A clinical research professional with 3+ years of on-site monitoring experience in the pharmaceutical or CRO industry
• Experienced monitoring Oncology specifically Myelofibrosis clinical trials.
• Proficient in ICH-GCP, local regulatory requirements, and clinical systems like CTMS and eTMF
• A clear communicator, problem-solver, and collaborative team player
• Willing and able to travel up to 50% for on-site monitoring visits across the West region; preference given to candidates residing near major HUB airport to support efficient regional travel.

Employment with ICON is contingent upon having the legal right to work in the country where the role is based.

ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.

Benefits may include:

• Competitive base salary and performance related incentives
• Health and wellbeing programmes including medical, dental, and vision coverage where applicable
• Retirement and pension plans
• Life assurance and disability coverage
• Employee assistance programmes and wellbeing resourcesLearning and development opportunities through structured training and career pathways

Benefits may vary depending on role and location.

Inclusion and Accessibility

ICON is an equal opportunity employer. We are committed to building an inclusive and accessible workplace where everyone feels valued and supported.

If you require reasonable accommodations during the recruitment process, please let us know or submit a request here.