Senior Clinical Trial Manager

Aveta Biomics Inc; Bedford (MA); On-site; USD 120,000 - 180,000; Full time

Job summary

Aveta Biomics Inc in Bedford, MA is seeking a Senior Clinical Trial Manager to lead planning, execution, and oversight of clinical studies. This on-site role requires coordinating investigators, sites, and vendors, ensuring GCP and regulatory adherence.

You will develop study timelines, monitor enrollment and data quality, review essential documents, manage study metrics, and drive process improvements with cross-functional teams including regulatory and data management.

Qualifications

• Leading Phase I–III trials with start-up, conduct and close-out.
• Strong knowledge of ICH-GCP, FDA requirements and trial best practices.
• Proficiency with CTMS, EDC and clinical operations tools.
• Excellent organizational and time-management skills.
• Clear written and verbal communication with stakeholders.

Responsibilities

• Plan, execute, and oversee clinical studies with timelines.
• Coordinate investigators, sites, vendors and CROs.
• Ensure adherence to protocols, GCP and regulatory requirements.
• Prepare and review key study documents, monitoring enrollment.
• Track study metrics and drive issue resolution and process improvements.

Skills

Clinical operations leadership

Project management

Cross-functional collaboration

Communication skills

Analytical thinking

Education

Bachelor's in life sciences or related

Advanced degree preferred

Tools

CTMS

EDC

Regulatory tools

Job description

Company Description Aveta Biomics Inc is a life sciences company headquartered at 110 Great Rd, Suite 302, in Bedford, Massachusetts, United States. The organization operates in a collaborative environment that supports the development and advancement of innovative biomedical solutions. Team members work closely across scientific and operational functions to drive high-quality research and clinical programs. The company values integrity, scientific rigor, and efficient execution, providing professionals with opportunities to contribute meaningfully to patient-focused innovation.

Role Description The Senior Clinical Trial Manager is a full-time, on-site role based in Bedford, MA, responsible for leading the planning, execution, and oversight of clinical studies. This position manages day-to-day trial activities, including developing study timelines, coordinating with investigators and sites, overseeing vendors and CROs, and ensuring adherence to protocols, GCP, and regulatory requirements. The role includes preparing and reviewing key study documents, monitoring enrollment and data quality, tracking study metrics, and resolving operational issues that may impact timelines or quality. The Senior Clinical Trial Manager will collaborate with cross-functional teams such as clinical operations, data management, biostatistics, regulatory, and medical to support study start-up, conduct, and close-out activities. This role also contributes to process improvements, risk management strategies, and best practices in clinical trial execution.

Qualifications

• Demonstrated experience leading and managing Phase I–III clinical trials, including study start-up, conduct, and close-out.
• Strong knowledge of ICH-GCP, FDA and international regulatory requirements, and clinical trial best practices.
• Proficiency in clinical trial management systems (CTMS), electronic data capture (EDC), and other clinical operations tools.
• Excellent organizational, project management, and time-management skills with the ability to prioritize multiple studies and deadlines.
• Advanced written and verbal communication skills for interaction with internal teams, sites, vendors, and regulatory stakeholders.
• Proven ability to lead cross-functional teams, mentor junior staff, and build productive relationships with investigators and vendors.
• Strong analytical and problem-solving skills, including the ability to interpret study data, identify risks, and implement mitigation plans.
• Bachelor’s degree in life sciences, nursing, pharmacy, or a related field; an advanced degree (e.g., MSc, MPH) is preferred.
• Several years of progressively responsible experience in clinical operations or trial management within biotech, pharma, or CRO settings.
• Comfort working in an on-site, collaborative environment in Bedford, MA, with flexibility to travel to investigator sites or meetings as needed.