Senior Clinical Research Scientist

ICON Strategic Solutions; United States; Remote; USD 140,000 - 210,000; Full time

Benefits offered by this job

Competitive base salary & incentives

Health and wellbeing programs

Retirement and pension plans

Life assurance & disability

Employee assistance programs

Learning and development opportunities

Job summary

ICON Strategic Solutions seeks a Senior Clinical Research Scientist (Oncology) to lead scientific execution of global oncology studies. You will partner with cross-functional teams on protocol design, safety monitoring, regulatory deliverables, and data interpretation to advance cancer therapies.

You will mentor junior scientists, collaborate with medical writers and operations, and support trial communication and publications while enabling remote work from the United States or Canada.

Qualifications

• BS/BA in Life Sciences with 7+ years of clinical research experience.
• MS or PhD in Life Sciences with 5+ years of clinical research experience.
• Significant clinical development experience (11+ years) in lieu of a Life Sciences degree.

Responsibilities

• Lead or support one or more clinical studies, depending on size and complexity.
• Serve as primary scientific contact for investigators, study teams, IRBs and stakeholders.
• Contribute to protocol design, endpoint development, and study strategy.
• Lead medical monitoring activities and SAE review oversight.
• Support SAC and DMC activities and adjudication processes.
• Collaborate on protocols, amendments, informed consent forms, and docs.
• Author protocol clarification letters and contribute to scientific communications.
• Provide scientific oversight for data review, safety monitoring, and data management.
• Monitor lab, imaging, and biomarker data for safety signals.
• Sign as scientific lead on Clinical Trial Teams and aid investigator meetings.

Skills

Lead Clinical Scientist

Oncology trials

Clinical trial design

Safety monitoring

Regulatory requirements

Data analysis

Excel

PowerPoint

Communication

Mentoring

Education

BS/BA Life Sciences

MS/PhD Life Sciences

11+ years clinical development

Job description

At ICON Strategic Solutions, you will work in a sponsor-dedicated model, supported by ICON's global expertise. As the world's largest FSP organization, with over 90 sponsor partnerships, we offer stability, career development and a collaborative environment where your work contributes to the development of treatments that benefit patients worldwide.

Senior Clinical Research Scientist (Oncology)

Travel: Up to 15% (including occasional international travel)

Are you an experienced Clinical Research Scientist with a passion for advancing oncology therapies? We are seeking a Senior Clinical Research Scientist to provide scientific leadership and clinical oversight across global oncology clinical trials. This is an exciting opportunity to partner with cross-functional teams and play a critical role in study design, execution, data interpretation, and regulatory deliverables that help bring innovative treatments to patients.

What You'll Do

As a key scientific leader, you will drive the clinical and scientific execution of oncology studies and serve as a trusted partner to internal and external stakeholders.

Key responsibilities include:

• Lead or support one or more clinical studies, depending on size and complexity.
• Serve as the primary scientific point of contact for investigators, study teams, IRBs, and other stakeholders.
• Contribute to protocol design, endpoint development, and study strategy in collaboration with Clinical Development.
• Lead medical monitoring activities, including Medical Monitoring Plan development and SAE review oversight.
• Support Safety Adjudication Committees (SAC), Data Monitoring Committees (DMC), and adjudication committees.
• Collaborate on the development and review of protocols, amendments, informed consent forms, and study-specific documentation.
• Author protocol clarification letters and contribute to scientific communications.
• Provide scientific oversight for clinical data review, safety monitoring, data management activities, and external data sources.
• Monitor laboratory, imaging, and biomarker data for safety signals and clinically significant findings.
• Serve as the scientific lead on Clinical Trial Teams and support investigator meetings through presentations and study training.
• Participate in database lock activities, clinical study reports (CSR), regulatory submissions, and publication planning.
• Review and classify protocol deviations and contribute to CSR documentation.
• Partner with medical writing, study management, and operational teams to ensure high-quality study execution and deliverables.
• Mentor and support junior Clinical Scientists as needed.

What We're Looking For

Required Qualifications

• BS/BA in Life Sciences with 7+ years of clinical research experience, OR
• MS or PhD in Life Sciences with 5+ years of clinical research experience, OR
• Significant clinical development experience (11+ years) in lieu of a Life Sciences degree.

Experience & Skills

Minimum 2 years of experience as a lead Clinical Scientist within pharmaceutical, biotechnology, or clinical drug development environments.

Oncology clinical trial experience required.

Medical monitoring experience required.

Strong understanding of:

• Clinical trial design and execution
• Clinical data review and interpretation
• Safety monitoring and regulatory requirements

Advanced proficiency in:

• Microsoft Excel
• PowerPoint
• Clinical data analysis and presentation

Exceptional written and verbal communication skills with the ability to collaborate across global, cross-functional teams.

Why Apply?

• Contribute to innovative oncology programs that have the potential to change patients' lives.
• Take on a highly visible scientific leadership role within clinical development.
• Collaborate with experienced clinical, medical, regulatory, and operational teams.
• Work remotely from anywhere in the United States or Canada.
• Be part of a dynamic environment where scientific expertise directly influences study success.

Employment with ICON is contingent upon having the legal right to work in the country where the role is based.

ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.

Benefits may include:

• Competitive base salary and performance related incentives
• Health and wellbeing programmes including medical, dental, and vision coverage where applicable
• Retirement and pension plans
• Life assurance and disability coverage
• Employee assistance programmes and wellbeing resources
• Learning and development opportunities through structured training and career pathways

Benefits may vary depending on role and location.

Inclusion and Accessibility

ICON is an equal opportunity employer. We are committed to building an inclusive and accessible workplace where everyone feels valued and supported.

If you require reasonable accommodations during the recruitment process, please let us know or submit a request here.