Senior Clinical Research Associate (CRA)

Zachary Piper Solutions; United States; Remote; USD 110,000 - 150,000; Full time

Job summary

Piper Companies is seeking a Senior Clinical Research Associate (CRA) to oversee clinical trial sites, ensure protocol and regulatory compliance, and support trial execution across oncology, cardiology, medical technology, and other areas.

The role entails on-site and remote monitoring, site performance reviews, risk identification, collaboration with investigators and cross-functional teams, and mentoring junior CRAs, with travel about 10-12 days per month.

Qualifications

• 3+ years of CRA experience in CRO/pharma/medical device environments.
• Bachelor's degree in scientific/healthcare field or related discipline.
• Willingness to travel about 10-12 days per month for on-site monitoring.
• Strong knowledge of ICH-GCP guidelines and FDA regulations.
• Experience in oncology studies preferred; other complex therapeutic areas welcome.
• Excellent communication, organizational, and relationship-management skills.

Responsibilities

• Conduct on-site and remote monitoring to ensure protocol, GCP, and regulatory compliance.
• Review site performance, source data quality, and trial integrity.
• Identify risks, protocol deviations, and implement corrective actions.
• Collaborate with investigators and cross-functional teams for enrollment and study execution.
• Mentor junior CRAs and guide sites on quality standards.
• Assist with audit preparation and CAPA activities.

Skills

Site Monitoring

GCP Compliance

Regulatory Knowledge

Clinical Ops

Communication

Travel Availability

Education

Bachelor's degree

Job description

Piper Companies is seeking a Senior Clinical Research Associate (CRA) to support a leading organization within the clinical research and biotechnology industry. The Senior Clinical Research Associate (CRA) will be responsible for overseeing clinical trial sites, ensuring compliance with study protocols and regulatory guidelines, and supporting successful trial execution across a variety of therapeutic areas, including oncology, cardiology, medical technology, and other complex focuses.

Responsibilities of the Senior Clinical Research Associate (CRA):

• Conduct on-site and remote monitoring visits to ensure compliance with study protocols, GCP guidelines, and specific regulatory requirements.
• Review site performance, source documentation, and data quality to maintain trial integrity and participant safety.
• Identify potential risks, protocol deviations, and operational challenges, implementing corrective actions when necessary.
• Partner with investigators, site staff, and cross-functional teams to support enrollment, study execution, and inspection readiness.
• Mentor junior CRAs and provide guidance to research sites on best practices and quality standards.
• Assist with audit preparation, CAPA activities, and ongoing process improvement initiatives.

Qualifications of the Senior Clinical Research Associate (CRA):

• 3+ years of Clinical Research Associate (CRA) experience within a CRO, pharmaceutical, biotechnology, or medical device environment.
• Bachelor's degree required in a scientific, healthcare, or related discipline.
• Ability to travel approximately 10-12 days per month for on-site monitoring activities.
• Strong understanding of ICH-GCP guidelines, FDA regulations, and clinical trial operations.
• Experience monitoring oncology studies preferred; candidates with experience in other complex therapeutic areas will also be considered.
• Excellent communication, organizational, and relationship-management skills.

Compensation for the Senior Clinical Research Associate (CRA) includes:

• Salary range: $110,000 - $150,000 depending on experience
• Comprehensive benefits package including medical, dental, vision, and retirement plans
• Location: West/West Coast based

This job opens for applications on 10/02/2026. Applications for this job will be accepted for at least 30 days from the posting date.

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