Senior Clinical Operations Lead – Site Monitoring

ProPharma; Raleigh (NC); Hybrid; USD 90,000 - 140,000; Full time

Job summary

ProPharma is seeking a Clinical Operations professional to oversee investigator site management and monitoring activities across assigned studies. You will lead the clinical monitoring teams with the client and internal teams, ensuring adherence to study plans, SOPs, and GCP/ICH guidelines.

You will also develop training materials and monitor data quality through site visits. The role requires advanced CRA skills, team leadership, and strong communication.

Qualifications

• 5+ years of clinical research experience.
• LCRA/Clinical Lead experience preferred.
• Excellent verbal and written communication skills.
• Experience using MS Office applications.

Responsibilities

• Oversight of investigator site management and monitoring activities for assigned studies.
• Lead site management resource for client, sites, and internal teams.
• Ensure monitoring activities comply with SOPs, GCP/ICH, and regulations.
• Contribute to study training materials and provide study-specific training.
• Quality review of site visit reports and monitoring deliverables.
• Collaborate with clinical project management to develop study plans and tools.
• Support site performance, recruitment, payments, and material needs.
• Provide status updates on initiations, enrollment, and visits.

Skills

CRA experience

Team leadership

Client relationships

Mentoring staff

Education

Bachelor’s degree

Tools

MS Office

eTMF/CTMS/EDC/DCT systems

Job description

ProPharma is seeking a Clinical Operations professional to oversee investigator site management and monitoring activities across assigned studies. You will lead the clinical monitoring teams with the client and internal teams, ensuring adherence to study plans, SOPs, and GCP/ICH guidelines.

You will also develop training materials and monitor data quality through site visits. The role requires advanced CRA skills, team leadership, and strong communication.