Senior Clinical Data Manager for High-Impact IVD Trials

Remote; San Francisco (CA); On-site; USD 110,000 - 160,000; Full time

Job summary

DELFI Diagnostics, Inc. is seeking an experienced contract Clinical Data Manager to support the DELFI-L201 (CASCADE) IVD Clinical Validation study.

The role focuses on data quality, query resolution, and study data integrity. You'll manage data cleaning, discrepancy handling, DV/TFL specifications assistance, and collaboration with cross-functional teams to ensure timely database locks and study milestones.

Qualifications

• 3-5+ years of hands-on clinical data management experience in pharma/diagnostic or CRO.
• Direct experience supporting database lock activities in clinical trials.
• Proficiency with Medidata Rave EDC.
• Ability to work independently with strong organizational, written, and verbal communication skills.
• Senior level requires 5+ years of CDM with DV/TFL spec experience.

Responsibilities

• Perform ongoing data cleaning and query management in the study EDC and data collection systems.
• Conduct data review, discrepancy management, medical coding support, and reconciliation activities.
• Translate data quality reports into queries and resolutions.
• Support CRF freeze/lock readiness and database lock preparation.
• Participate in study team meetings and provide brief weekly status summaries.

Skills

Data management

Clinical data management

Medidata Rave

Data cleaning

Query management

CRF resolution

Communication skills

Independent worker

Tools

Medidata Rave EDC

Clario

AI tools (Claude Code, Gemini)

Job description

DELFI Diagnostics, Inc. is seeking an experienced contract Clinical Data Manager to support the DELFI-L201 (CASCADE) IVD Clinical Validation study.

The role focuses on data quality, query resolution, and study data integrity. You'll manage data cleaning, discrepancy handling, DV/TFL specifications assistance, and collaboration with cross-functional teams to ensure timely database locks and study milestones.