Senior Biostatistician - Phase III Oncology (Remote)

Greenhouse Software, Inc.; Northern (KY); Hybrid; USD 120,000 - 190,000; Full time

Job summary

ClinChoice is seeking a Senior/Principal Biostatistician to support Phase III oncology trials remotely, delivering statistical analyses, creating TFLs, and contributing to ADaM specifications in collaboration with Statistical Programming.

Ideal candidates hold an MS/PhD in statistics, have hands-on Phase III oncology experience, and are proficient in OS, PFS, ORR, DoR, censoring, Kaplan-Meier, Cox models, and SAS; strong communication and independence are essential.

Qualifications

• Advanced degree (MS, PhD, or equivalent) in Statistics, Biostatistics, or a related quantitative field.
• Direct hands-on experience supporting at least one Phase III oncology clinical trial.
• Strong understanding of oncology clinical trial endpoints, including OS, PFS, ORR, and DoR.
• Strong knowledge of censoring rules and time-to-event analysis.
• Hands-on experience with Kaplan-Meier, Cox Proportional Hazards, and stratified log-rank methods.
• Strong SAS programming skills with the ability to review statistical programming outputs and perform independent checks.
• Experience authoring or reviewing TFL and ADaM specifications and collaborating closely with Statistical Programming.
• Strong problem-solving skills with the ability to identify and resolve discrepancies in analysis outputs.
• Ability to work independently, quickly onboard to new studies, and operate effectively with minimal supervision.
• Demonstrated ability to manage deliverables across multiple concurrent clinical trials while maintaining quality and timelines.
• Excellent written and verbal communication skills.

Responsibilities

• Provide statistical expertise and hands-on support for Phase III oncology clinical trials.
• Contribute to study design, statistical analysis, interpretation of results, and clinical study deliverables.
• Demonstrate a strong understanding of key oncology endpoints, including OS, PFS, ORR, and DoR.
• Apply and interpret methods for censoring and time-to-event analyses.
• Author, review, and provide input into TFL and ADaM specifications in collaboration with Statistical Programming.
• Review statistical programming outputs, identify discrepancies, and work with programmers to resolve issues.
• Use SAS to independently review outputs and perform data and analysis checks.
• Manage deliverables across multiple concurrent clinical studies, ensuring timelines and quality.
• Work independently with minimal supervision and collaborate with cross-functional teams as required.
• Support interim analyses and IDMC/DMC activities, including preparation and review of DMC outputs.

Skills

Independent work

Strong communication

Cross-functional collaboration

Statistical design

Problem solving

Education

MS/PhD in Statistics or Biostatistics

Tools

SAS

R

Job description

ClinChoice is seeking a Senior/Principal Biostatistician to support Phase III oncology trials remotely, delivering statistical analyses, creating TFLs, and contributing to ADaM specifications in collaboration with Statistical Programming.

Ideal candidates hold an MS/PhD in statistics, have hands-on Phase III oncology experience, and are proficient in OS, PFS, ORR, DoR, censoring, Kaplan-Meier, Cox models, and SAS; strong communication and independence are essential.