Senior Biostatistician – Oncology Biomarker Analytics

Orion Corporation; Cambridge (MA); On-site; USD 100,000 - 180,000; Full time

Job summary

Orion Pharma in the United States is seeking a Senior Biostatistician to provide statistical leadership across Phase I–III oncology studies, with emphasis on biomarker and precision medicine analyses. You will collaborate with Clinical Development, Translational Medicine, Data Sciences, and external partners to deliver robust statistical solutions.

The role requires expertise in SAS, R, and CDISC standards, with experience in integrating AI-enabled approaches to improve workflows and decision

Qualifications

• PhD or MS in Statistics/Biostatistics or related field.
• Experience in oncology clinical development preferred.
• Proficiency in SAS is required; working knowledge of R encouraged.

Responsibilities

• Contribute to design and statistical sections of protocols, including endpoint selection and sample size.
• Analyze biomarker data to inform development decisions and patient selection.
• Integrate clinical and biomarker findings to generate actionable insights.
• Plan and execute statistical analyses per SAPs.
• Generate tables, listings, and figures (TLFs) and ensure CDISC SDTM/ADaM compliance.
• Support regulatory documents and study reporting.
• Collaborate with cross-functional teams throughout the study lifecycle.
• Evaluate AI-assisted tools to improve efficiency and insights.

Skills

SAS

R

Biostatistics

Clinical trials

AI-enabled analytics

Education

MS in Statistics/Biostatistics

PhD in Statistics

Job description

Orion Pharma in the United States is seeking a Senior Biostatistician to provide statistical leadership across Phase I–III oncology studies, with emphasis on biomarker and precision medicine analyses. You will collaborate with Clinical Development, Translational Medicine, Data Sciences, and external partners to deliver robust statistical solutions.

The role requires expertise in SAS, R, and CDISC standards, with experience in integrating AI-enabled approaches to improve workflows and decision