Senior Bioprocess Engineer: Upstream/Downstream Lead

KBI BioPharma Inc.; Durham, Northern (NC, KY); Hybrid; USD 120,000 - 170,000; Full time

Job summary

KBI Biopharma, Inc. in Durham, NC seeks a Process Engineer III to lead and optimize biopharma manufacturing processes.

You will apply engineering principles to scale-up upstream and downstream operations, specify equipment needs, and drive continuous improvements with cross-functional teams. You will own qualification activities, support tech transfer, and ensure GMP compliance across projects, with a focus on reliability, yield, and product quality in a fast-paced biologics production

Qualifications

• Bachelors degree in chemical or biochemical engineering or related field.
• Proficiency with process modeling and simulation tools.
• Strong problem-solving, communication, and analytical skills.

Responsibilities

• Lead scale-up of upstream/downstream processes (cell culture, purification).
• Own qualification activities for new/modified equipment and processes.
• Support tech transfer, CAPA, and GMP compliance across projects.

Skills

Process modeling

Cross-functional leadership

Regulatory familiarity

Analytical problem solving

Education

Bachelor's in chemical/biochemical engineering

Tools

Process modeling software

Job description

KBI Biopharma, Inc. in Durham, NC seeks a Process Engineer III to lead and optimize biopharma manufacturing processes.

You will apply engineering principles to scale-up upstream and downstream operations, specify equipment needs, and drive continuous improvements with cross-functional teams. You will own qualification activities, support tech transfer, and ensure GMP compliance across projects, with a focus on reliability, yield, and product quality in a fast-paced biologics production