Senior Bioinformatics Research Scientist

St. Jude Children's Research Hospital, Inc.; Memphis (TN); On-site; USD 104,000 - 186,000; Full time

Job summary

St. Jude Children's Research Hospital in Memphis seeks a Senior Bioinformatics Research Scientist to advance pharmacogenomics through EHR-driven phenotyping.

You will develop informatics tools leveraging terminology, NLP, and ML to enable deep phenotyping across large biobank and internal data. The role requires collaboration with clinicians and data scientists to co-develop high-throughput phenotyping solutions.

Qualifications

• Bachelor’s degree in bioinformatics or related field with 7+ years of relevant post-degree experience.
• Master’s degree with 5+ years, or PhD with 2+ years of relevant experience.
• Experience in at least one programming language and one statistical package (R preferred).

Responsibilities

• Provide research support with an efficient analytical approach using available data.
• Deliver data files and document the analytical process.
• Contribute to manuscript preparation when projects conclude.
• Help establish protocols and best practices for common tasks.
• Evaluate and test new methods and technologies.
• Suggest automations to improve analysis.
• Collaborate on interdepartmental projects.
• Maintain regular and predictable attendance.

Skills

Programming languages

R

Education

Bachelor's degree in bioinformatics or related field

Master's degree with 5+ years

PhD with 2+ years

Job description

Job Summary

St. Jude is seeking a Senior Bioinformatics Research Scientist for data science projects within the Center for Pharmacogenomics in the Department of Pharmacy and Pharmaceutical Sciences. In particular, this individual will focus on electronic health record (EHR)-driven phenotyping to support pharmacogenomics discovery research. The successful candidate will be responsible for developing and implementing new informatics tools and resources to enhance phenotyping performance or enable deep phenotyping through terminology/ontology, natural language processing, and machine learning. The role involves working with large external biobank datasets such as All of US, eMERGE, TopMed, UK BioBank, as well as internal EHR data. This Bioinformatics Research Scientist will collaborate extensively with disease and/or drug experts (clinicians, clinician scientists, data scientists, and laboratory investigators) to co-develop phenotyping algorithms but is expected to serve as the domain expert in high-throughput phenotyping. Demonstrated expertise in EHR-based phenotype extraction and curation are strongly preferred.

Responsibilities

• Provide research support and deliver high-quality results by formulating an efficient analytical approach with the available data.
• Deliver data files, and document the analytical process.
• May participate in manuscript preparation at project's conclusion.
• Assist with establishing and documenting protocols or best practices for common research tasks, and in the formulation of analytical plans that use the best approach to address challenging data analysis questions.
• Assist in the evaluation and testing of new methods and technologies.
• Contribute ideas to automate or improve existing analysis methods. Implement the improvement or work with others to do so.
• Participate in the department's developmental projects and interdepartmental team projects.
• Perform other duties as assigned to meet the goals and objectives of the department and institution.
• Maintains regular and predictable attendance.

Qualifications

• Minimum Requirement: Bachelor's degree with 7+ years of relevant post-degree work experience in relevant area (e.g., bioinformatics, cheminformatics, statistics/computer science with a background in biological sciences or chemistry) (OR) Master's degree with 5+ years of relevant experience (OR) PhD with 2+ years of relevant experience.
• Significant experience in at least one programming or scripting language and at least one statistical package, with R preferred.
• Minimum Education and/or Training: Bachelor's degree in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry) or related field. Master's degree or PhD preferred.
• Minimum Experience: Master's degree with 5+ years of relevant post-degree experience (OR) PhD with 2+ years of relevant post-degree experience.

Compensation

In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $104,000 - $186,160 per year for the role of Senior Bioinformatics Research Scientist. Explore our exceptional benefits!

Equal Opportunity Employer / Search Firm Notice

St. Jude is an Equal Opportunity Employer. No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.