Senior Backend Engineer - JS, AI & Native App Support

Caraa; United States; Remote; USD 100,000 - 140,000; Full time

Job summary

A health tech startup in the United States seeks an experienced Senior Backend Engineer to design and maintain high-performance backend services. The role involves collaborating on AI-driven projects and optimizing systems for mobile applications. Ideal candidates will have expert skills in TypeScript and significant experience with databases. Join a fully remote team committed to transforming personal genomics.

Benefits

Remote work flexibility

Collaborative team culture

Opportunity to work on innovative projects

Qualifications

• 5+ years of backend development experience.
• Experience with functional programming.
• Experience supporting and scaling native mobile app backends.

Responsibilities

• Design, build, and maintain performant backend services in TypeScript.
• Support and optimize backend systems for mobile native applications.
• Collaborate with the lead AI backend engineer to shape our AI infrastructure.

Skills

Expert-level proficiency in TypeScript

Deep experience with PostgreSQL

Deep experience with MySQL

Strong background integrating with AI tools

Strong debugging skills

Job description

Job Posting: Senior Backend Engineer

Company: Sequencing.com

Sequencing.com is on a mission to make advanced whole genome sequencing accessible and actionable for everyone. We are a startup at the intersection of SaaS, eCommerce, and health tech—offering DNA testing kits, secure DNA data storage, and a growing marketplace of reports and proprietary AI tools that help people understand their genetic data.

We are a small, fast-moving team that values clarity, autonomy, and high standards. We’ve grown quickly and are now looking for a full-time Senior Backend Engineer to join the team behind SequencingAI — our advanced chat‑based experience that delivers personalized insights and recommendations based on a user’s genetic data. You will be building high-performance services and infrastructure that power our AI‑driven features, all tailored using the latest research and our proprietary One Genome technology.

The Role

In this role, you will support the backend for our mobile native apps, collaborating closely with the lead backend engineer responsible for our AI infrastructure. You will also take co‑ownership of new systems and features — from design and implementation to deployment and optimization. We seek someone who thrives on autonomy but values close collaboration when it counts. Above all, you are customer‑obsessed and quality‑driven.

What You’ll Do

• Design, build, and maintain performant backend services in TypeScript.
• Support and optimize backend systems for mobile native applications.
• Integrate and manage services like PostgreSQL, MySQL, AWS SQS, and Centrifugo.
• Work with OpenAI APIs and other AI frameworks to build intelligent, personalized user experiences.
• Collaborate with the lead AI backend engineer to shape and evolve our AI infrastructure.
• Ensure high system reliability, security, and observability across services.
• Own and drive end‑to‑end feature development with a strong eye on user experience.
• Champion clean code, technical excellence, and continuous improvement.

What We’re Looking For

• 5+ years of backend development experience.
• Expert‑level proficiency in TypeScript.
• Experience with functional programming.
• Deep experience with PostgreSQL, MySQL, and service‑based architectures.
• Strong background integrating with AI tools, especially OpenAI.
• Experience supporting and scaling native mobile app backends.
• Proven ability to work independently while closely collaborating with key teammates.
• Passion for building systems that deliver exceptional customer experiences.
• Strong debugging, testing, and performance‑tuning skills.

Bonus Points if You Have

• Experience with agentic AI frameworks like LangGraph.
• Experience with AWS Bedrock, Google AI, DeepSeek (R1 model preferred).
• Familiarity with genomics, health data, or personalization systems.
• Prior work on chatbots or conversational interfaces.
• Startup or fast‑paced environment experience.
• Familiarity with Rust.

Location

• Remote

About Sequencing

Sequencing is powering the future of personalized health. We are the platform that transforms a person’s genome into a lifelong source of straightforward, actionable insights—for individuals, families, and healthcare professionals. By providing the application layer to your DNA, we turn complex genetic data into recurring value throughout every stage of life.

Our unique, clinical‑grade Whole Genome Sequencing unlocks the most complete view of your DNA, screening for almost all known health conditions, traits, and medication responses—translating that information into clear, actionable steps for managing health risks, optimizing wellness, and extending longevity.

As whole genome sequencing becomes a standard part of life, Sequencing is already the trusted platform where people safely store their DNA data—and will become the lifelong home for every genome on Earth.

We are a fully remote, global team of innovators, scientists, and builders, united by a mission to make genomics accessible, actionable, and life‑changing for everyone.

Proudly named GenomeWeb’s Best Place to Work in 2024, Sequencing is venture‑backed and scaling rapidly to meet surging demand in the fast‑growing personal genomics market.

If you are excited to help redefine how the world thinks about health, join us in building the platform that brings every genome to life.

Equal Opportunity Employer

Sequencing Inc. is an equal opportunity employer. All aspects of employment, including the decision to hire, promote, discipline, or discharge, will be based on merit, competence, performance, and business needs. We do not discriminate based on race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical condition, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, state, or local law.