Senior Automation Engineer — Scale Bioassays & GMP Systems

BioSpace

Norwood (MA)

On-site

USD 122,000 - 195,000

Full time

14 days+
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Benefits offered by this job

Best-in-class healthcare coverage
Well-being resources
Family planning benefits
Paid time off, volunteer days, sabbat2
Savings and investment opportunities
Location-specific perks and extras

Job summary

Moderna in Norwood, MA, seeks a Senior Engineer I to advance automation for high-throughput, GMP-compliant bioassays. You will transform early-stage automation into scalable systems, collaborating with scientists to ensure cell health, sterility, and timing precision.

You’ll own project execution from requirements to sustainment in a fully onsite role. You will work with Analytical Development, Digital and QC to deploy validated automation, ensure data integrity, and optimize performance across

Qualifications

  • BS with 8 years of relevant experience, MS with 5 years of relevant experience or PhD in Engineering, Biology, Biochemistry, Bioengineering, or related discipline.
  • Hands-on experience supporting or working with cell-based bioassays or sample preparation workflows.
  • Experience working in or supporting regulated laboratory environments. (GLP/GMP)
  • Experience programming and developing with laboratory automation software/hardware and liquid handlers.
  • This position is site-based, requiring you to be at Moderna’s site full-time. This position is not eligible for remote work.

Responsibilities

  • Lead the development and hardening of automated bioassay workflows, transforming early-stage prototypes into robust, scalable, GMP-ready systems.
  • Collaborate with scientists to translate cell-based bioassays and sample preparation workflows into automation solutions, accounting for biological constraints such as cell health, sterility, and timing sensitivity.
  • Design and implement automation strategies for cell handling workflows (e.g., maintenance, passaging, transfection, assay execution) to ensure reproducibility and assay integrity at scale.
  • Own technical execution across projects, including requirements definition, system integration, testing, deployment, and sustainment.
  • Partner cross-functionally with Analytical Development, Applied Technologies, Analytical Sciences & Technology, Digital, and QC Operations to enable successful transfer and deployment of systems into regulated environments.
  • Develop automation solutions that meet GMP expectations, including data integrity, traceability, and audit readiness.
  • Troubleshoot complex issues across biological performance, liquid handling, and system integration layers, including investigation of assay variability and automation-induced bias.
  • Drive standardization and continuous improvement of automation platforms and workflows to support scalability across programs.

Skills

Automation software
Bioassays
Cell handling
GMP/GLP
Programming automation hardware
Liquid handling

Education

Engineering/Biology/biochemistry/bioengineering PhD/MS/BS

Tools

Hamilton STAR/Vantage
HighRes Cellario

Job description

Moderna in Norwood, MA, seeks a Senior Engineer I to advance automation for high-throughput, GMP-compliant bioassays. You will transform early-stage automation into scalable systems, collaborating with scientists to ensure cell health, sterility, and timing precision.

You’ll own project execution from requirements to sustainment in a fully onsite role. You will work with Analytical Development, Digital and QC to deploy validated automation, ensure data integrity, and optimize performance across

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