Senior Associate Scientist - Molecular Biology

卡湯晩; Cambridge (MA); On-site; USD 73,000 - 123,000; Full time

Job summary

An innovative global healthcare company is seeking a Senior Associate Scientist in Molecular Biology to join their dynamic team. This role involves generating and managing DNA plasmids critical for antibody discovery and engineering. The successful candidate will utilize advanced molecular biology techniques and collaborate with a dedicated team to enhance drug discovery processes. With a commitment to improving lives through science, this position offers a wealth of opportunities for professional growth and development in a supportive environment. Join a company where your contributions can make a real difference in the world of healthcare.

Benefits

Health and wellbeing benefits

High-quality healthcare

Parental leave

Career growth opportunities

Employee benefit programs

Qualifications

• Strong molecular biology skills for recombinant DNA plasmid generation.
• Experience with plasmid construct design and cloning strategies.
• Ability to manage and track DNA constructs in databases.

Responsibilities

• Generate and manage DNA plasmids for antibody discovery and engineering.
• Support high-throughput molecular biology activities.
• Troubleshoot complex cloning strategies and maintain data integrity.

Skills

Molecular biology skills

Gateway cloning technology

InFusion cloning technology

Gibson Assembly cloning technology

Agarose gel electrophoresis

DNA purification

DNA sequencing

Sequence analysis

Excellent oral and written communication skills

Education

BS in Biology

MS in Biology

Tools

Sequencher

VectorNTI

SnapGene

MOSAIC

LIMS

Genedata Biologics

Job description

Job Title: Senior Associate Scientist - Molecular Biology

Location: Cambridge, MA

About the Job

Are you ready to shape the future of medicine? The race is on to speed up drug discovery and development to find answers for patients and their families. Your skills could be critical in helping our teams accelerate progress.

The person in this position will work as part of the Molecular, Expression and Screening Technologies (MEST) Group within Sanofi’s rapidly expanding North America R&D Large Molecule Research organization. The individual will be part of a group that has the responsibility to generate, store and distribute DNA plasmids for a wide range of down-stream activities.

We are an innovative global healthcare company with one purpose: to chase the miracles of science to improve people’s lives. We’re also a company where you can flourish and grow your career, with countless opportunities to explore, make connections with people, and stretch the limits of what you thought was possible. Ready to get started?

Main Responsibilities:

• The successful candidate must have strong molecular biology skills. The position is part of the core molecular biology team that provides recombinant DNA plasmids needed for antibody discovery, antibody engineering, protein production and cell line generation. This person will also be responsible for tracking all DNA constructs generated in our global sample databases (Genedata Biologics, CloneDB) and our global freezer tracking system (MOSAIC).

• In addition to producing plasmids requested de novo, this person will also assist with the plasmid and data management activities within the group. We are a global repository for the majority of DNA constructs generated over time and have implemented a global system for requesting these stored plasmids. Responsibilities will include retrieval of stored DNA plasmid, handling all outsourcing of DNA upscaling at a CRO, QC of newly generated DNA batches and subsequent delivery to requestors. In addition, the candidate will be responsible for processing new batches of DNA along with meta data entry into the Global Repository and freezer tracking system. The candidate will also support the High-throughput Molecular Biology team by generating DNA plasmids at a large scale as needed.

• This person must have strong molecular biology skills with the ability to understand and execute complex cloning strategies. The scientist in this position must have the ability to troubleshoot and resolve problems in which initiative and judgment are required; the ability to work in a fast-paced environment while maintaining a high level of attention to detail; the ability to organize and present data, the ability to work in a collaborative team environment and to communicate effectively both within the immediate group and across groups.

About You

Knowledge and Skills:

Required

• Molecular biology skills including Gateway, InFusion and Gibson Assembly cloning technologies, knowledge in plasmid construct design (including antibodies), agarose gel electrophoresis, DNA purification, DNA sequencing and sequence analysis

• Knowledge of molecular biology software such as Sequencher, VectorNTI or SnapGene

• Possess excellent oral and written skills

Preferred

• Experience with sample registration (MOSAIC), LIMS (Laboratory Information Management System) and biological registration systems (example: Genedata Biologics)

Experience Required:

• BS or MS in biology or related field and 1-5 years of experience in a research laboratory or a biopharma/biotech company.

Why Choose Us?

• Bring the miracles of science to life alongside a supportive, future-focused team.

• Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.

• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.

• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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Pursue progress, discover extraordinary

Better is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people.

At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, ability or gender identity.

Watch our ALL IN video and check out our Diversity Equity and Inclusion actions at sanofi.com!

US and Puerto Rico Residents Only

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally inclusive and diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; natural or protective hairstyles; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

North America Applicants Only

The salary range for this position is:

$73,500.00 - $122,500.00

All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs. Additional benefits information can be found through the LINK.