Senior Associate, Downstream Biotech Manufacturing (12-Hour Shift)

Biopharma Careers; Holly Springs (MS); On-site; USD 86,000 - 116,000; Full time

Job summary

Amgen seeks a Senior Associate Manufacturing for Bulk Drug Substance Downstream (Days) to support 24/7 operations on a 12‑hour 2‑2‑3 shift schedule. You will perform on‑the‑floor downstream operations, ensure cGMP adherence, and drive process improvements with cross‑functional teams in a high‑volume pharma environment.

Responsibilities include operating chromatography, TFF, viral filtration, and inactivation steps; completing EBRs, maintaining clean facilities, and contributing to continuous

Qualifications

• High School Diploma/GED with 4 years in manufacturing or regulated environments.
• Associate's Degree with 2 years in manufacturing or regulated environments.
• Bachelor's Degree with 6 months in manufacturing or regulated environments.
• Master's Degree considered as preferred qualification.

Responsibilities

• Execute downstream biotech operations (Column Chromatography, Tangential Flow Filtration, Viral Filtration and Inactivation) on the floor.
• Perform setup, operation, cleaning, sanitization, and monitoring of equipment and EB R processes.
• Complete in-process sampling, operate analytical equipment, and document results in Electronic Batch Records (EBR).
• Maintain safety, cGMP compliance, and quality; escalate issues as needed.

Education

High School Diploma/GED + 4 years manufacturing or regulated environment experience

Associate’s Degree + 2 years manufacturing or regulated environment experience

Bachelor’s Degree + 6 months manufacturing or regulated environment experience

Master's Degree

Job description

Amgen seeks a Senior Associate Manufacturing for Bulk Drug Substance Downstream (Days) to support 24/7 operations on a 12‑hour 2‑2‑3 shift schedule. You will perform on‑the‑floor downstream operations, ensure cGMP adherence, and drive process improvements with cross‑functional teams in a high‑volume pharma environment.

Responsibilities include operating chromatography, TFF, viral filtration, and inactivation steps; completing EBRs, maintaining clean facilities, and contributing to continuous