Senior AI/ML Cheminformatics Scientist

Merck & Co.; Cambridge (MA); Vor Ort; USD 160.000 - 251.000; Vollzeit

Zusammenfassung

Merck & Co., Inc. invites applications for a Senior Specialist, Modeling & Informatics to join the Cheminformatics group within M&I. The role develops AI/ML and cheminformatics methods and applies them to drug discovery, collaborating with diverse teams to drive pipeline impact.

You will publish findings and advance target discovery using state-of-the-art tools, contributing to a global R&D program and innovative science.

Qualifikationen

• Experience applying cheminformatics or AI/ML approaches to drug discovery.
• Broad understanding of modern data science methods, particularly machine learning, e.g., predictive modeling, active learning, explainable ML.
• Proficiency in scripting (Python and/or R), SQL, and cheminformatics toolkits (OEChem, RDKit, DeepChem).

Aufgaben

• Implement and apply AI/ML and cheminformatics workflows to analyze early target discovery data.
• Analyze, interpret, and summarize complex chemical biology data with visualization tools.
• Deliver optimized informatics algorithms and workflows to expedite drug discovery pipelines for small molecules, peptides, and degraders.
• Leverage ML, statistics, and cheminformatics to improve hit identification across screening paradigms.
• Integrate internal and external knowledge to identify biological and chemical signatures.
• Engage with cross-functional teams of experimental and computational scientists to advance projects.
• Continue research in AI/ML and cheminformatics for drug discovery and evaluate new tech and software.
• Communicate results internally and externally via presentations and publications.
• Share AI/ML and data engineering knowledge to boost team capabilities.

Kenntnisse

Academic Research

Algorithms

Biological Data Analysis

Biomarker Discovery

Biovia Pipeline Pilot

Chemical Informatics

Computational Biology

Data Analysis

Data Management

Data Modeling

Data Visualization

Drug Discovery Research

KNIME

Machine Learning (ML)

Python (Programming Language)

Scientific Research

Scientific Writing

TIBCO Spotfire

Virtual Screening

Ausbildung

Ph.D. in cheminformatics, bioinformatics, computational biology or chemistry, computer science, statistics or related fields

Tools

OEChem

RDKit

DeepChem

Databricks

AWS

TensorFlow

Keras

PyTorch

Pandas

Scikit-Learn

KNIME

Pipeline Pilot

Jobbeschreibung

Merck & Co., Inc. invites applications for a Senior Specialist, Modeling & Informatics to join the Cheminformatics group within M&I. The role develops AI/ML and cheminformatics methods and applies them to drug discovery, collaborating with diverse teams to drive pipeline impact.

You will publish findings and advance target discovery using state-of-the-art tools, contributing to a global R&D program and innovative science.