Senior AI-Driven AppSec Engineer

112 Cardinal Health 5, LLC; United States; On-site; USD 125,000 - 179,000; Full time

Job summary

Cardinal Health, Inc. is seeking an Application Security Engineer, AI and Agentic Security, to design, prototype, and operationalize AI-enabled security within our software development lifecycle.

This senior individual contributor role blends hands-on engineering with deep Application Security expertise to advance secure AI practices. You will collaborate with security, software, cloud, and governance teams to move innovations from experiments to governed enterprise capabilities, balancing

Qualifications

• Bachelor's degree in computer science, software engineering, cybersecurity, information systems, or a related field, or equivalent practical experience.
• Substantial experience in software engineering, security engineering, Application Security, DevSecOps, or a closely related technical discipline.
• Demonstrated proficiency developing solutions in Python.
• Demonstrated understanding of Application Security concepts and secure software development practices.
• Experience delivering complex technical work with limited definition and coordinating across multiple stakeholder groups.
• Hands-on experience with generative AI application development, LLM integration, agentic systems, or AI-enabled developer tooling.
• Experience with one or more additional languages or platforms such as Java, JavaScript/TypeScript, .NET/C#, or Go.
• Experience with cloud services, containers, Kubernetes, infrastructure as code, and enterprise developer platforms.
• Experience with AI evaluation, adversarial testing, red teaming, observability, or governance controls for AI-enabled systems.
• Knowledge of industry guidance such as the OWASP Top 10, NIST frameworks, and AI risk management.

Responsibilities

• Design, build, and test prototypes and production-ready capabilities using generative AI, large language models, AI agents, and multi-step agentic workflows.
• Develop Python-based services, automation, integrations, evaluation harnesses, and supporting tools for Application Security use cases.
• Evaluate AI-enabled security products and frameworks for vulnerability discovery, exploitability analysis, secure code guidance, remediation, validation, and developer workflow integration.
• Create controlled workflows in which AI capabilities can analyze code, use approved tools, recommend or generate changes, execute tests, and produce auditable evidence while maintaining appropriate human oversight.
• Establish technical guardrails for agent identity, least privilege, data access, tool use, repository access, secrets handling, logging, traceability, change control, and safe failure or termination.
• Develop test plans and benchmarks to assess accuracy, security, reliability, repeatability, cost, latency, false positives, remediation quality, and operational value.
• Perform security testing of AI and agentic workflows, including prompt injection, unsafe tool use, excessive agency, data leakage, insecure output handling, dependency and supply chain risks, and authorization failures.
• Integrate capabilities with source control, CI/CD pipelines, developer tools, issue management, security testing platforms, and vulnerability management workflows.
• Define reference architectures, reusable patterns, technical requirements, runbooks, and operational support models for approved capabilities.
• Partner with governance and architecture teams to ensure solutions align with enterprise AI, security, privacy, data protection, and technology standards.
• Support pilots with application teams, capture feedback, measure outcomes, and recommend whether capabilities should be scaled, redesigned, purchased, built, or retired.
• Maintain awareness of developments in generative AI, agentic systems, secure AI engineering, Application Security, and software delivery practices.
• Strong hands-on Python development experience, including API integration, automation, testing, data handling, and production-quality engineering practices.
• Experience building or integrating solutions using large language models, model APIs, retrieval-augmented generation, tool calling, structured outputs, workflow orchestration, or agent frameworks.
• Experience designing and evaluating agentic workflows that use tools, maintain state, make bounded decisions, and operate with human approval where appropriate.
• Strong understanding of secure software development, common application vulnerabilities, threat modeling, secure design, authentication and authorization, secrets management, and software supply chain risk.
• Experience with Application Security capabilities such as SAST, SCA, secrets detection, DAST, API security, container security, IaC security, and vulnerability remediation workflows.
• Experience with Git-based development, pull requests, CI/CD, automated testing, containers, Kubernetes, and cloud-native development patterns.
• Ability to evaluate AI output quality using repeatable test cases, metrics, red-team scenarios, and evidence-based comparison rather than demonstration results alone.
• Understanding of AI security risks and controls, including prompt injection, data leakage, excessive agency, insecure tool use, model and dependency supply chain risk, and auditability.
• Strong problem-solving, technical writing, presentation, and cross-functional collaboration skills.
• Ability to move between experimental engineering and enterprise operationalization without losing sight of maintainability, governance, cost, and support requirements.

Skills

Python development

Generative AI

AI/Agentic security

DevSecOps

Cloud services

Kubernetes

CI/CD

Security testing

Cross-functional collaboration

Education

Bachelor's degree in CS/SE/cybersecurity or equivalent

Tools

Git-based development

Containers (Docker)

Kubernetes

CI/CD pipelines

Job description

Cardinal Health, Inc. is seeking an Application Security Engineer, AI and Agentic Security, to design, prototype, and operationalize AI-enabled security within our software development lifecycle.

This senior individual contributor role blends hands-on engineering with deep Application Security expertise to advance secure AI practices. You will collaborate with security, software, cloud, and governance teams to move innovations from experiments to governed enterprise capabilities, balancing