Senior AI Bio Capabilities Verification Scientist

SecureBio; United States; Remote; USD 195,000 - 300,000; Full time

Benefits offered by this job

Comprehensive healthcare

Flexible work schedule

Professional development opportunities

401(k) match

Referral bonus

Job summary

SecureBio, LLC is hiring a Senior Research Scientist to design and run in vitro capability-verification experiments used by the Foundational Research team to test how in silico model performance translates to real biology.

We evaluate AI-enabled biology with novel capabilities and publish findings for AI firms, researchers, and policymakers. You will join a growing team building a new BSL-2 lab and shaping the program as a pivotal early member.

Qualifications

• A PhD in virology, molecular biology, synthetic biology, protein design, or a closely related field, plus several years of post-PhD experience.
• Hands-on wet-lab depth in at least one relevant area, with the ability to interface across the others.
• Past experience working with ≥ BSL-2 agents.
• Strong experimental design skills: power analysis, controls, and confound management, applied to small-n studies.
• Calibrated judgment about biological risk.
• Comfort with novel, non-standardized work where you define the method, and with short, intensive project cycles that shift with model releases.
• Commitment to research ethics, documentation, and reproducibility.
• Comfort handling confidential and sensitive biosecurity information with discretion.
• Alignment with SecureBio's mission of preventing catastrophic pandemics.
• Practical experience with biological AI tools (protein design models, sequence models, or similar).

Responsibilities

• Design and run in vitro validations of capabilities demonstrated computationally, with rapid turnarounds to inform pre-release decisions.
• Own experimental design rigor across verification studies: power, controls, bias mitigation, replicability, and confound management.
• Translate candidate verification tasks into executable experiments, choosing informative and safe proxy systems.
• Critically assess results in the context of major threat models.
• Work with evals team to turn verification findings into in silico correlates, making wet-lab evidence cost-effective.
• Oversee wet lab technical team in study implementation and execution.
• Contribute to specification and biological task design for AI uplift studies of human biology performance.
• Design and execute demonstrations for policymakers and frontier labs with rigor and clarity for non-specialists.
• Contribute to reports, papers, and public dashboards of AI biology capabilities trends.

Skills

PhD in relevant field

Wet-lab expertise

BSL-2 experience

Experimental design

Biological risk judgment

Innovative methods

Research ethics & reproducibility

Confidential information handling

Mission alignment

Biological AI tools experience

Education

PhD in virology, molecular biology, synthetic biology, protein design or related field

Tools

Benchling

LIMS software

Python

R

Liquid-handling automation

Claude Code / Codex

Job description

SecureBio, LLC is hiring a Senior Research Scientist to design and run in vitro capability-verification experiments used by the Foundational Research team to test how in silico model performance translates to real biology.

We evaluate AI-enabled biology with novel capabilities and publish findings for AI firms, researchers, and policymakers. You will join a growing team building a new BSL-2 lab and shaping the program as a pivotal early member.