Self Healing Supply Chain Senior Director

AstraZeneca plc; Gaithersburg (MD); Hybrid; USD 178,000 - 266,000; Full time

Benefits offered by this job

Incentives

Equity-based awards

Health, dental & vision

Retirement programs

Paid time off

Job summary

AstraZeneca plc in Gaithersburg, MD is seeking a Senior Director for the Self-Healing Supply Chain program to shape how a global biopharmaceutical supply chain senses disruption, makes better decisions and learns from outcomes, so patients receive medicines when they need them. This hybrid role advances strategy, governance and delivery across a multi-location team.

Reporting to the Executive Director, Digital Supply Chain, you will build internal capability, scale high-value use cases and hand

Qualifications

• Bachelor's Degree required.
• 10+ years leading large-scale digital transformation programs with cross-functional teams, ideally in supply chain planning or logistics.
• Experience with Decision Intelligence or AI-enabled decision portfolios.
• Experience with ERP/APS platforms and partnership with IT.
• Ability to scale internal capability and move delivery from external partners to business ownership.
• Experience with decision intelligence platforms.

Responsibilities

• Set the SHSC vision and roadmaps; define decisions to support and level of autonomy.
• Lead day-to-day program management and line-manage core team.
• Shape the roadmap for the Decision Intelligence platform and ERP write-back.
• Deliver measurable business value and track benefits with accountable owners.
• Grow internal Decision Architecture capability and move delivery in-house.
• Engage senior leaders and partners; manage performance and knowledge transfer.
• Maintain risk and KPI frameworks, oversee ERP transformation and data readiness.
• Redesign roles and adapt to ensure adoption and value realization.

Skills

Decision Architecture

AI-enabled decisions

Digital transformation

Supply chain planning

Stakeholder leadership

ERP and planning systems

Change management

Education

Bachelor's Degree

MBA degree

Tools

ERP/SAP (S/4HANA)

Resilinc

One Network

Celonis

Neo4j knowledge graphs

project44

Job description

Self Healing Supply Chain Program Sr. Director (SHSCPD)

Gaithersburg, MD

Global Supply Chain

Hybrid Work - on average 3 days/week in office

As Senior Director of the Self-Healing Supply Chain program, you will shape how a global biopharmaceutical supply chain senses disruption, makes better decisions and learns from every outcome, so that patients receive the medicines they need, when they need them. The Self-Healing Supply Chain (SHSC) program is a core part of our Intelligent Supply ambition. It follows a Sense, Assess, Heal and Learn loop, using AI and end-to-end enterprise data to detect issues, assess impact, simulate scenarios, recommend actions and learn from outcomes. The program brings together Decision Intelligence, a supply chain digital twin and knowledge graph, risk sensing and an AI-powered supply chain assistant, with control tower capabilities in development.

This is a pivotal moment to join. As the program moves into 2027, the focus shifts from building capabilities to scaling them. You will lead one integrated portfolio, scale high-value use cases, hand mature products over to business ownership and build internal capability for the long term. Throughout, you will treat the business decision, not the technology, as the unit of transformation, and measure success by evidenced business value and sustained adoption.

Reporting to the Executive Director, Digital Supply Chain, you will lead a multi-location core team of Decision Architects, workstream leads and change and communications specialists, and direct a wider delivery network across IT, data, business services and external partners. This is a global role, working alongside our other Intelligent Supply pillars, AI Development Agent (AIDA) and Autonomous Manufacturing, to deploy technology consistently across Global Operations. You will provide the decision, data and insight capabilities that the business adopts through existing processes, while Quality, Regulatory and operational decisions remain with the accountable teams.

What You’ll Do

• Set the strategy: Set the SHSC vision, strategy and decision roadmap, defining which decisions to support, augment or automate, and the right level of autonomy for each. Lead annual integrated planning to deliver one prioritized, resourced portfolio.
• Spearhead the program: Lead day-to-day program management and line-manage the core team. Chair steering committees, integrated plan reviews and quarterly benefit reviews, and lead a fixed-capacity delivery model in which scope flexes to available capacity.
• Champion Decision Intelligence: Steer the Decision Architecture discipline so every use case starts from a clearly defined business decision. Shape the roadmap for our Decision Intelligence platform, including controlled write-back to ERP and planning systems and the progression from human-in-the-loop to human-on-the-loop automation, while keeping decision design platform-independent.
• Deliver measurable value: Implement a governed intake, assessment and prioritization process with clear decision gates. Build compelling business cases and track benefits through accountable business owners, measuring adoption as well as delivery.
• Build lasting capability: Grow internal Decision Architecture capability through secondments and a common accreditation pathway, and guide the move from partner-led delivery to internal ownership without disrupting work in flight.
• Engage stakeholders and partners: Build trusted relationships with senior leaders, business functions and strategic technology partners, owning partner performance, commercial value and knowledge transfer.
• Handle risk and performance: Maintain risk and KPI frameworks, lead critical dependencies such as ERP transformation, data readiness and integration architecture, and apply risk-based human oversight suited to a GxP-regulated environment.
• Lead change and adoption: Redesign roles, routines and decision rights so planners move from collecting data to managing exceptions, build trust through explainable recommendations, and transfer mature capabilities into business ownership with clear exit criteria and ongoing review of value and adoption.

Essential for the role

• Bachelor's Degree
• 10+ years leading large-scale digital transformation programs with cross-functional teams, ideally in supply chain planning or logistics.
• Deep understanding of end-to-end supply chain operations and business processes, ideally in a complex, regulated manufacturing environment.
• Experience in decision-centric design (Decision Architecture), breaking complex operational decisions into triggers, logic, trade-offs and guardrails.
• Experience leading Decision Intelligence or AI-enabled decision portfolios from MVP to scale-up and business-as-usual operation, including human-in-on-the-loop governance and write-back to ERP and planning systems.
• Management-level experience of digital supply chain platforms (e.g., ERP, APS) and a record of effective partnership with IT.
• Track record of building internal capability, moving delivery from external partners to business ownership, and shaping data and architecture demand (data products, knowledge graphs, AI-ready data).
• Experience with decision intelligence platforms

Desirable for the role

• MBA degree
• Pharmaceutical or healthcare industry experience, including the regulatory environment.
• Experience in a global role handling international supply chain challenges.
• Proficiency in Agile methods and structured project management frameworks.
• Familiarity with supply chain technologies such as OMP, SAP (including S/4HANA), Resilinc, project44, One Network, Celonis, Neo4j knowledge graphs and Optilogic.

Office Working Requirements

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That’s why we work, on average, a minimum of three days per week from the office. But that doesn’t mean we’re not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

The annual base pay for this position ranges from $177,652.80 - 266,479.20 USD. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.

Date Posted

09-Nov-2026

Closing Date

19-Nov-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.