Scientist, Solid-State Characterization

Eurofins; Groton (CT); On-site; USD 34,000 - 41,000; Full time

Benefits offered by this job

Medical, Dental & Vision

Life & Disability Insurance

401(k) with company match

Paid vacation & holidays

Job summary

Eurofins in Groton, CT is seeking an Associate Scientist to support solid-state analysis of drug candidates. You will perform XRD, DSC, moisture sorption, microscopy and spectroscopy to evaluate salt forms and polymorphs for drug substances.

You will partner with multidisciplinary teams to design screening campaigns, characterize particles and surfaces, and document results in the electronic lab notebook, contributing to formulation and clinical study readiness.

Qualifications

• BS with 2+ years of experience or MS/PhD in pharmaceutical science, chemistry, chemical engineering, or related field.
• Experience in solid state characterization techniques (such as x-ray powder diffraction, polarized light microscopy, differential scanning calorimetry, thermogravimetric analysis, spectroscopy, etc.). Strong data analysis and interpretation skills.
• Experience and understanding of infrared spectroscopy (FTIR, NIR, FT-Raman) and/or SSNMR is an advantage.
• Experience with solving Materials Science problems, e.g., solid state chemistry and particle characterization using experimental approaches and team collaboration.
• Understanding of physical, analytical, and organic chemistry.
• Good organizational skills, the ability to work independently, and excellent oral and written communication skills are required.
• A strong interest and motivation to learn new technologies and concepts is expected.
• Some programming experience is a plus, but not required.

Responsibilities

• Conduct solid state characterization (e.g., X-ray powder diffraction, thermal analysis, moisture sorption, microscopy, spectroscopy) of small molecules of pharmaceutical relevance.
• Support multidisciplinary project teams and collaborate with colleagues to define and implement crystallization, polymorph, salt, and co-crystal screening activities according to project timelines.
• Support multidisciplinary project teams and collaborate with colleagues to define and implement API particle characterization activities according to project timelines.
• Conduct physical and surface characterization of powders of pharmaceutical relevance. This includes particle characterization (e.g., particle size, shape) and surface characterization (e.g., surface energy, surface roughness).
• Collaborate with colleagues in Medicinal Chemistry, Formulation and Biopharmaceutics to define and implement screening and characterization strategies consistent with solid form selection for clinical studies.
• Solve scientific problems using contemporary Materials Science experimental techniques.
• Contribute to the development of new scientific approaches and knowledge within the Materials Science organization.
• Ensure contemporaneous and accurate entries are made in the electronic laboratory notebook system according to accepted good practice.

Skills

Solid-state characterization

Data analysis

Independent work

Communication skills

Problem solving

Education

Bachelor’s Degree in pharmaceutical science, chemistry, chemical engineering, or related field

Master’s degree in related field

PhD in related field

Tools

X-ray powder diffraction

DSC

TGA

FTIR/NIR/FT-Raman

SSNMR

Polarized light microscopy

Job description

• Compensation: USD 25 - USD 30.5 - hourly

Company Description

Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins laboratories work with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate.

The Eurofins network of companies is the global leader in food, environment, pharmaceutical and cosmetic product testing and in agroscience Contract Research Organisation services. It is one of the market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, advanced material sciences and in the support of clinical studies, as well as having an emerging global presence in Contract Development and Manufacturing Organisations. It also has a rapidly developing presence in highly specialised and molecular clinical diagnostic testing and in-vitro diagnostic products.

In over 30 years, Eurofins has grown from one laboratory in Nantes, France to 58,000 staff across a decentralised and entrepreneurial network of 900 laboratories in over 54 countries. Eurofins companies offer a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability and purity of biological substances and products.

In 2021, Eurofins generated total revenues of EUR 6.72 billion, and has been among the best performing stocks in Europe over the past 20 years.

Job Description

The Associate Scientist provides laboratory support in synthesizing salt forms and polymorphs of drug candidates and evaluates these forms for acceptability as drug substances with respect to chemical manufacturing and formulation into pharmaceutical products. The successful candidate will engage in solid form characterization and in particle characterization. The position is based in Groton, CT (USA).

Role Responsibilities

• Conduct solid state characterization (e.g., X-ray powder diffraction, thermal analysis, moisture sorption, microscopy, spectroscopy) of small molecules of pharmaceutical relevance.
• Support multidisciplinary project teams and collaborate with colleagues to define and implement crystallization, polymorph, salt, and co-crystal screening activities according to project timelines.
• Support multidisciplinary project teams and collaborate with colleagues to define and implement API particle characterization activities according to project timelines.
• Conduct physical and surface characterization of powders of pharmaceutical relevance. This includes particle characterization (e.g., particle size, shape) and surface characterization (e.g., surface energy, surface roughness).
• Collaborate with colleagues in Medicinal Chemistry, Formulation and Biopharmaceutics to define and implement screening and characterization strategies consistent with solid form selection for clinical studies.
• Solve scientific problems using contemporary Materials Science experimental techniques.
• Contribute to the development of new scientific approaches and knowledge within the Materials Science organization.
• Ensure contemporaneous and accurate entries are made in the electronic laboratory notebook system according to accepted good practice.

Qualifications

• Bachelor’s Degree (BS) with 2+ years of experience or a Master’s degree (MS) or a PhD in pharmaceutical science, chemistry, chemical engineering, or related field.
• Experience in solid state characterization techniques (such as x-ray powder diffraction, polarized light microscopy, differential scanning calorimetry, thermogravimetric analysis, spectroscopy, etc.). Strong data analysis and interpretation skills.
• Experience and understanding of infrared spectroscopy (FTIR, NIR, FT-Raman) and/or SSNMR is an advantage.
• Experience with solving Materials Science problems, e.g., solid state chemistry and particle characterization using experimental approaches and team collaboration.
• Understanding of physical, analytical, and organic chemistry.
• Good organizational skills, the ability to work independently, and excellent oral and written communication skills are required.
• A strong interest and motivation to learn new technologies and concepts is expected.
• Some programming experience is a plus, but not required.

Additional Information

• The position is full-time, M- F 8 am to 5 pm
• May be requested to work on weekends, overtime, and holidays based on business needs.
• Candidates currently living within a commutable distance of Groton, CTare encouraged to apply.
• Excellent full-time benefits, including comprehensive medical coverage, dental, and vision options
• Life and disability insurance
• 401(k) with company match
• Paid vacation and holidays
• #LI-EB1

Eurofins USA PSS Insourcing Solutions is a Disabled and Veteran Equal Employment Opportunity employer.