Scientist Senior #26-26960

Us Tech Solutions; South San Francisco (CA); On-site; USD 120,000 - 180,000; Full time

Job summary

US Tech Solutions is seeking a senior scientist to lead multiparametric flow cytometry work in a biomarker laboratory. You will develop and qualify clinical assays, advancing them from discovery to CRO validation and monitoring ongoing studies.

The role requires designing experiments, analyzing data, and documenting protocols with minimal supervision while ensuring compliance with clinical study guidelines and regulations. The position is a 12-month contract based in South San Francisco, CA.

Qualifications

• PhD, PharmD or MD with 2+ years of experience OR a Master’s with 5 years OR a Bachelor’s with 7 years.
• Experience with multiparametric flow cytometry in a clinical biomarker setting is required.
• Proficiency with FlowJo, FCS Express, OMIQ.AI, SPADE, viSNE and CITRUS is expected.

Responsibilities

• Develop and qualify biomarker assays using multiparametric flow cytometry for clinical programs.
• Advance biomarker assays from discovery through CRO validation and clinical study monitoring.
• Plan experiments, document protocols/results, and analyze data with minimal supervision.
• Ensure studies comply with protocols and applicable regulations.

Skills

Conventional flow cytometry

Spectral flow cytometry

Flow cytometry data analysis

Education

PhD/MD/PharmD with 2+ years OR Master's 5+ years OR Bachelor's 7 years

Tools

FlowJo

FCS Express

OMIQ.AI

SPADE

viSNE

CITRUS

Job description

Job Responsibilities

• The successful candidate is expected to employ multiparametric flow cytometry in our biomarker laboratory to develop and qualify biomarker assays to support various clinical programs.
• The team is responsible for advancing biomarker assays from research and discovery through clinical development, CRO validation, and ongoing clinical study monitoring.
• Specific responsibilities associated with the job include independent thinking, choosing the appropriate platform, planning and performing laboratory experiments, documenting experimental protocols and results, and analyzing and interpreting data.
• With minimal supervision, plans, conducts or monitors experiments, records and organizes data, analyses results, generates robust and reliable data and/or ensures that contracted studies are conducted in compliance with the respective protocol and applicable guidelines and regulations.

Duration: 12 months contract

Shift: Monday-Friday, 8:00 AM-5:00 PM

Key Responsibilities

• Develop and optimize complex flow cytometry assays for clinical applications.
• Perform hands-on wet lab experimentation, including antibody evaluation, titrations, and assay troubleshooting.
• Support transfer of assays to CRO partners for validation.
• Review CRO-generated data and provide technical guidance.
• Evaluate flow cytometry gating strategies and cell population identification.
• Identify assay performance issues and recommend adjustments.
• Support data quality control throughout clinical studies.
• Collaborate with internal research teams, laboratory leads, and CRO partners.
• Adapt quickly to shifting program priorities and business needs.

Basic Qualifications

• PhD, PharmD, or MD with 2 years of experience; OR
• Master’s degree with 5 years of experience; OR
• Bachelor’s degree with 7 years of experience.

Top Must Have Skill Sets

• Experience with both conventional and spectral flow cytometry in clinical biomarker setting.
• A strong background and experience in multiparametric flow cytometry assays including immunophenotyping, receptor occupancy and immune based functional assays.
• Experience with complex data analysis software for flow cytometry such as FlowJo, FCS Express, OMIQ.AI, SPADE, viSNE and CITRUS

Additional Must Have Skills

• Extensive hands-on flow cytometry experience is essential.
• Must have direct experience with complex multiparameter flow cytometry, ideally 15-30 color panels.
• Strong knowledge of flow cytometry instrumentation, experimental design, gating, and data analysis.
• Must independently perform experiments, analyze results, and troubleshoot technical issues.
• Conceptual exposure or limited experience with basic 2-3 color flow cytometry is insufficient.
• Candidate should be capable of contributing with minimal foundational training.

Preferred Skills

• Clinical biomarker development.
• Clinical assay validation and optimization.
• CRO collaboration and technical oversight.
• Experience in biotechnology, pharmaceutical, academic, or clinical research environments.
• Flow cytometry core laboratory experience.
• Experience transitioning assays from discovery research to clinical testing.
• Clinical biomarker experience is strongly preferred but not an absolute requirement if the candidate possesses substantial hands-on technical expertise.

About US Tech Solutions

US Tech Solutions is a global staff augmentation firm providing a wide range of talent on-demand and total workforce solutions. To know more about US Tech Solutions, please visit www.ustechsolutions.com.

US Tech Solutions is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, colour, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran

By applying, you acknowledge that AI-assisted tools may be used during hiring.