Scientist, Quantitative Systems Pharmacology

Biopharma Careers; United States; Hybrid; USD 122,000 - 177,000; Full time

Job summary

Sanofi Inc. in Morristown, NJ is seeking a Scientist, Quantitative Systems Pharmacology to build multiscale mechanistic models and support model-informed drug discovery in early development.

You will survey literature, integrate preclinical and clinical data, document workflows, and communicate predictions to stakeholders to drive research decisions.

Qualifications

• PhD in relevant field with strong publications and at least 2 years postdoctoral experience in disease modeling/QSP.
• Proficiency in mathematical modeling using differential equations.
• Experience with computational tools such as MATLAB, Julia and R (MATLAB preferred).

Responsibilities

• Develop and apply multiscale computational models of complex diseases to support model-informed drug discovery and development.
• Survey literature to identify physiological processes and suitable mechanistic elements, data, parameters and assumptions.
• Identify and analyze internal preclinical and clinical data to inform modeling activities.
• Analyze simulation results and resolve model performance issues.
• Maintain documentation of model development and data analysis.
• Communicate modeling predictions to key stakeholders.

Skills

Mathematical modeling

Communication skills

Team collaboration

Education

PhD in systems pharmacology/biology/computational biology/biomedical engineering

Master's degree + 4+ years industry experience

Tools

MATLAB

Julia

R

Job description

Job title: Scientist, Quantitative Systems Pharmacology

Location: Morristown, NJ

About the Job

The Quantitative Systems Pharmacology (QSP) group of Sanofi is seeking to hire a highly talented modeling scientist to support its portfolio in early clinical development. The QSP group is part of Translational Informatics department within the Translational Medicine and Early Development organization of Sanofi. The individual will primarily be involved with hands‑on quantitative systems pharmacology modeling activities, and he/she will be responsible to work with internal and external collaborators to ensure alignment with the strategic needs of the project team. The position will be based in Morristown, NJ.

Join the engine of Sanofi’s mission, where deep immunoscience meets bold, AI-powered research. In R&D, you’ll drive breakthroughs that could turn the impossible into possible for millions.

About Sanofi:

We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives.

Main responsibilities:

• Function as part of a team to develop and apply multiscale computational models of complex diseases based on detailed biological mechanistic knowledge to support model-informed drug discovery & development.
• Survey literature to gain understanding of critical physiological processes to be represented, and identify suitable mechanistic elements, data, parameters and assumptions to be included.
• Identify and analyze suitable internal preclinical and clinical data to inform modeling activities.
• Analyze simulation results and identify appropriate strategies to resolve issues pertaining to model performance and accuracy.
• Maintain extensive documentation of model development process, and data analysis.
• Maintain quantitative systems pharmacology expertise through comprehensive education.
• Communicate modeling predictions to key stakeholders.

About You

PhD in systems pharmacology/biology, computational biology, biomedical engineering, or a related field with a strong record of productivity demonstrated through publications and scientific presentations with at least 2 years of Postdoctoral experience in disease modeling/QSP. Master’s degree with 4+ years of relevant industry experience.

Proficiency in mathematical modeling using differential equations.

Extensive experience in computational tools such as MATLAB, Julia and R (MATLAB preferred).

Desirable Qualifications:

• Experience in drug discovery/development a plus, especially in bioinformatics or pharmacometrics.
• Knowledge of Immunology.

Soft Skills:

• Excellent oral and written communication skills.
• Ability to quickly learn pathophysiology in indications of interest, and treatment approaches in immunology.
• Highly motivated, detail-oriented, and independent researcher.
• Able to thrive in a collaborative, multi-disciplinary team environment.
• Strong commitment to on-the-job-training.

Why Choose Us

• Bring the miracles of science to life alongside a supportive, future-focused team.
• Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.
• Enjoy a thoughtful, well-crafted rewards package that recognises your contribution and amplifies your impact.
• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and welfare programs and at least 14 weeks’ gender-neutral parental leave.
• Be part of a pioneering biopharma company that engages patients early in drug development and uses their insights to design studies that reflect real-world needs.
• Help improve the lives of millions of people globally by making drug development quicker and more effective.
• Work at the forefront of drug discovery, harnessing cutting‑edge AI, data, and digital platforms to push the boundaries of science.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Aff…

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Pursue progress , discover extraordinary

Better is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people.

At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, ability or gender identity.

Watch our ALL IN video and check out our Diversity Equity and Inclusion actions at sanofi.com !

US and Puerto Rico Residents Only

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Aff…

North America Applicants Only

The salary range for this position is:

$122.250,00 - $176.583,33

All compensation will be determined commensurate with demonstrated experience.

Employees may be eligible to participate in Company employee benefit programs.

Additional benefits information can be found through the LINK .