Scientist, Preclinical

Terrestrial Bio, Inc.; Woburn, Northern (MA, KY); Ibrido; USD 110.000 - 130.000; Tempo pieno

Descrizione del lavoro

Terrestrial Bio, Inc. in Woburn, MA, is seeking a Scientist, Preclinical to own the scientific side of preclinical studies, designing experiments, analyzing data, and reporting insights.

You will work with the in vivo team and study manager to execute studies and compile longitudinal data, presenting results to stakeholders to inform model development. A PhD with 2+ years of relevant experience is preferred.

Competenze

• PhD in Biomedical Engineering, Pharmacology, or a related field with 2+ years of relevant experience. Industry experience is preferred; postdoctoral experience will be considered.
• Quantitative Analysis: Demonstrated experience with noncompartmental PK analysis and statistical analysis of biological variability.
• Study Design: Experience designing in vivo studies, including endpoint selection and determining group sizes.
• Tissue Characterization: Hands-on experience with tissue mechanical testing, ex vivo tissue models, or related characterization methods.
• Scientific Writing: A record of clear technical writing, such as study reports, publications.
• Communication: Ability to present data and recommendations clearly to both scientific and non-scientific audiences.
• Preferred Skills: Programming in R or Python, Phoenix WinNonlin, experience with transdermal, intradermal, or microneedle delivery, and exposure to IND-enabling work.

Mansioni

• Study Design: Author in vivo and ex vivo study designs and protocols, defining endpoints, group sizes, sampling schedules, and analysis plans.
• Skin Characterization: Lead the design and analysis of skin property studies.
• Variability Analysis: Quantify animal-to-animal and study-to-study variability, identify where it comes from, and recommend design changes that reduce it.
• PK & Statistical Analysis: Perform noncompartmental PK analysis and statistical analysis of study data, and present findings to the program team.
• Study Reports: Write study reports and technical summaries, and contribute to the nonclinical sections of regulatory documents.
• Scientific Oversight: Provide scientific oversight of studies in progress, working with the in vivo team and study manager to keep execution aligned with the design.
• Cross-Functional Support: Bring preclinical data and interpretation to Formulation, Device Engineering, and Analytical, and contribute to broader company efforts as priorities require.

Conoscenze

Quantitative Analysis

Study Design

Tissue Characterization

Scientific Writing

Communication

Programming in R/Python

Phoenix WinNonlin

Transdermal/Intr dermal/Microneedle

IND-enabling experience

Formazione

PhD in Biomedical Engineering or Pharmacology

Descrizione del lavoro

Terrestrial is building a team of exceptional people to rapidly advance products to patients. We work closely as a team and thrive in a dynamic, exciting, and engaging work environment. We aim to recruit, employ, train, compensate and promote regardless of race, religion, color, national origin, sex, gender identity or expression, sexual orientation, disability, age, or veteran status.

Please note: We have been made aware that individuals unaffiliated with Terrestrial have posed as hiring managers to solicit personal information. Terrestrial does not conduct any recruiting through online chat services or message boards. Terrestrial does not request any personal financial information before an on-site interview. Please use care and discretion when receiving any solicitations that do not originate from the @terrestrialbio.com domain.

Scientist, Preclinical

Location

Woburn, MA

Address

30 Cummings Park Dr, Woburn, MA, 01801

Employment Type

Full time

Location Type

On-site

Department

Research & Development

About Terrestrial Bio, Inc.

Terrestrial is transforming the delivery of next-generation therapies, starting with GLP-1.

Terrestrial's proprietary Tacterra™ microarray patch (MAP) and applicator platform consists of a patch resembling an adhesive bandage, which is applied with a preloaded applicator and removed after a few minutes. Once applied, each patch delivers bioactive tips into the skin, which dissolve quickly into the body, rapidly releasing their therapeutic payload. Designed for self-administration, the temperature-stable Tacterra™ platform enables precise, controlled delivery of a wide range of therapeutics without medical sharps or refrigeration.

Terrestrial has generated strong clinical and in-vivo proof of concept across multiple molecules. For more information, visit www.terrestrialbio.com .

Why this role

You will own the scientific side of our preclinical studies: designing them, analyzing the data, and reporting what it means. You will work with our in vivo team and study manager on execution, and with stakeholders across the company on the questions the data needs to answer. You will compile data summaries to discern longitudinal trends and present them to the stakeholders to enrich our understanding of the models we rely on.

What you’ll do

• Study Design: Author in vivo and ex vivo study designs and protocols, defining endpoints, group sizes, sampling schedules, and analysis plans.
• Skin Characterization:Lead the design and analysis of skin property studies.
• Variability Analysis:Quantify animal-to-animal and study-to-study variability, identify where it comes from, and recommend design changes that reduce it.
• PK & Statistical Analysis: Perform noncompartmental PK analysis and statistical analysis of study data, and present findings to the program team.
• Study Reports:Write study reports and technical summaries, and contribute to the nonclinical sections of regulatory documents.
• Scientific Oversight: Provide scientific oversight of studies in progress, working with the in vivo team and study manager to keep execution aligned with the design.
• Cross-Functional Support: Bring preclinical data and interpretation to Formulation, Device Engineering, and Analytical, and contribute to broader company efforts as priorities require.

Who you are

• Education & Experience: PhD in Biomedical Engineering, Pharmacology, or a related field with 2+ years of relevant experience. Industry experience is preferred; postdoctoral experience will be considered.
• Quantitative Analysis:Demonstrated experience with noncompartmental PK analysis and statistical analysis of biological variability.
• Study Design:Experience designing in vivo studies, including endpoint selection and determining group sizes.
• Tissue Characterization:Hands-on experience with tissue mechanical testing, ex vivo tissue models, or related characterization methods.
• Scientific Writing:A record of clear technical writing, such as study reports, publications.
• Communication: Ability to present data and recommendations clearly to both scientific and non-scientific audiences.
• Preferred Skills:Programming in R or Python, Phoenix WinNonlin, experience with transdermal, intradermal, or microneedle delivery, and exposure to IND-enabling work.

Preferred Skills: Programming in R or Python, Phoenix WinNonlin, experience with transdermal, intradermal, or microneedle delivery, and exposure to IND-enabling work.

Compensation:

The anticipated base salary range for this position is $110,000 - $130,000. Actual compensation will be determined based on a variety of factors including experience, qualifications, and internal equity.

Onsite expectations:

The majority of our roles at Terrestrial are onsite, which allows us to meet both business and team needs. Candidates applying must be willing to be onsite 4-5 days per week.

Location:

Woburn, MA and our new, custom facility in Allston MA planned for Q4 of 2026.

At Terrestrial, we’re bringing together exceptional talent to drive our product development forward. We value collaboration, curiosity, and a dynamic work environment. We aim to recruit, employ, train, compensate and promote regardless of race, religion, color, national

Join a Team on
the Forefront of Biomedical Innovation.

“Working at Terrestrial was unlike any other research experience I’ve had so far. Not only was I a part of cutting edge research, but I felt like the work I was doing contributed to their goals.”