Scientist, Physico-Chem Analytics (Mass Spectrometry)

GSK; Cambridge (MA); On-site; USD 89,000 - 149,000; Full time

Job summary

A global biopharmaceutical company in Cambridge, Massachusetts, is seeking a Scientist specializing in Physico-Chemical Characterization (Mass Spectrometry). You will develop techniques to characterize mRNA, DNA, and proteins, maintaining comprehensive documentation and collaborating with teams. Candidates should have an MS or PhD in relevant fields, with experience in mass spectrometry. The role offers a competitive salary and additional benefits.

Benefits

Health care benefits

Retirement benefits

Paid holidays

Paid caregiver/parental and medical leave

Qualifications

• 3+ years lab experience for MS candidates; PhD candidates need no additional lab experience.
• 2+ years of experience in mass spectrometry technologies.

Responsibilities

• Develop LC-MS and LC-MS/MS methods to characterize biomolecules.
• Perform routine biophysical characterization.
• Maintain electronic lab notebooks and documentation.

Skills

Mass spectrometry-based technologies

Analytical method development

Biophysical characterization

Cross-functional teamwork

Strong communication skills

Education

MS or PhD in Chemistry, Biology, Biochemistry, Biotechnology, or related field

Job description

Scientist, Physico-Chemical Characterization (Mass Spectrometry)

At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. R&D is committed to discovering and delivering transformational vaccines and medicines to prevent and change the course of disease. GSK has invested in expanding its R&D space in Cambridge, Massachusetts, to build a new hub for mRNA‑based vaccine discovery and develop state‑of‑the‑art analytical methods.

Key Responsibilities

• Develop LC‑MS and LC‑MS/MS methods to characterize mRNA, DNA, proteins, N‑glycans, lipids, and vaccine components.
• Perform routine biophysical characterization using LC‑MS, LC‑MS/MS, UHPLC, CGE, light scattering, particle characterization, spectroscopy, calorimetry or compendial tests as needed.
• Prepare samples for characterization studies.
• Maintain comprehensive electronic lab notebooks and documentation records.
• Deliver reproducible and impactful results under ambitious timelines.
• Execute and troubleshoot standard protocols, and develop new protocols to improve assays.
• Act as an active member of a high‑performing team of top scientists driven by innovation, quality and excellence.
• Contribute to a culture of excellence, transparency and collaboration within the global organization.
• Develop next‑generation analytical methods for mRNA vaccines in collaboration with Preclinical, DS and DP teams.

Basic Qualifications

• MS or PhD in Chemistry, Biology, Biochemistry, Biotechnology, Bioengineering, Chemical Engineering or a related scientific field.
• For MS candidates, three or more years of additional laboratory experience; for PhD candidates, no additional laboratory experience is required.
• Two or more years of experience in mass spectrometry‑based technologies of biomolecules (mRNA, DNA, or proteins).

Preferred Qualifications

• Experience with mRNA‑LNP vaccine analytics or vaccine development.
• Strong theoretical and practical background in proteomics and biophysical characterization methodologies.
• Good understanding of biopharma/vaccine development process.
• Proven ability to work effectively within cross‑functional and multidisciplinary teams.
• Strong verbal and written communication skills; good presentation skills.
• Fluency in English.

Salary and Benefits

The annual base salary for this position ranges from $89,100 to $148,500, plus an annual bonus and eligibility to participate in our share‑based long‑term incentive program. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave.

Equal Opportunity Employer

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

Contact

If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1‑877‑694‑7547 (US Toll Free) or [phone] (outside US).