Scientist, Machine Learning

Korro Bio, Inc.; Cambridge (MA); On-site; USD 82,000 - 197,000; Full time

Benefits offered by this job

Equity-based compensation

Medical, dental, vision insurance

401(k) retirement plan

Life insurance

Health savings account

Job summary

A biotechnology firm in Cambridge is seeking a Scientist in Machine Learning to develop models for RNA-based therapeutics. The ideal candidate will work on innovative ML algorithms, collaborate with scientists, and engage in AI projects that drive forward drug design. A PhD or relevant MS degree is required, along with experience in machine learning and deep learning frameworks. This position offers competitive compensation and a comprehensive benefits package.

Qualifications

• PhD with 0-3 years of experience, or MS with 5+ years in AI, computer science, or bioinformatics.
• Familiarity with structural biology/chemistry of RNA and proteins.
• Expert knowledge of transformer architectures like T5, BERT, GPT.

Responsibilities

• Design and implement novel machine learning architectures for drug design.
• Collaborate with scientists to build models for RNA biology insights.
• Deploy ML solutions in collaboration with IT and Engineering teams.

Skills

Machine Learning

Deep Learning

Algorithm Development

Data Analysis

Communication Skills

Education

PhD or MS in AI or related field

Tools

PyTorch

TensorFlow

JAX

Job description

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Company Summary: Korro is a biopharmaceutical company focused on developing a new class of genetic medicines for both rare and highly prevalent diseases using its proprietary RNA editing platform. Korro is generating a portfolio of differentiated programs that are designed to harness the body’s natural RNA editing process to effect a precise yet transient single base edit. By editing RNA instead of DNA, Korro is expanding the reach of genetic medicines by delivering additional precision and tunability, which has the potential for increased specificity and improved long-term tolerability. Using an oligonucleotide-based approach, Korro expects to bring its medicines to patients by leveraging its proprietary platform with precedented delivery modalities, manufacturing know-how, and established regulatory pathways of approved oligonucleotide drugs. Korro’s lead program is Alpha-1 Antitrypsin Deficiency (AATD). Korro is based in Cambridge, Massachusetts.

We are collaborative and united by a common mission. We are building a company with extraordinary people with an audacious vision to create transformative genetic medicines for prevalent diseases. Our values - Rewrite the future, On the Cutting Edge, Better Together, Dynamically Different, Kindness and Integrity form the fabric of the organization. They are reinforced daily and serve as key dimensions in the hiring process to help us ensure that Korro is a magnet for outstanding talent and a great place to work. Join us as we redefine what's possible in genetic medicine and work to make a lasting impact on human health.

Position Summary: As a Scientist in our Machine Learning group, you will work to develop the next generation of models to push forward RNA-based therapeutics and accelerate our ability to bring drugs to patients. We are looking for an established researcher in Machine Learning, capable of developing novel deep learning algorithms applied to our proprietary biological data, and working with our larger scientific team to drive forward our ML system capabilities.

Key Responsibilities

• Design and implement novel transformer-based machine learning architectures to push forward our drug design programs.
• Collaborate with our laboratory scientists to build models that most effectively inform our internal stakeholders of key insights into mechanisms of RNA biology.
• Collaborate with our IT and Engineering teams to effectively deploy ML solutions to the organization at large.
• Design and implement methodologies allowing for improved usage and comprehension of complex models by internal stakeholders.
  
  

Required Qualifications

• PhD with 0-3 years of experience, or MS with 5+ years of experience in artificial intelligence, computer science, computational biology, computational chemistry, bioinformatics, or a related field.
• Familiarity with structural biology/chemistry (of DNA, RNA and/or proteins)
• Knowledge of the drug development process.
• Expert knowledge of SOTA transformer architectures, including but not limited to T5, BERT, GPT, PaLM2, etc.
• Experience training large models at scale, including distributed training strategies.
• Established experience in machine learning algorithm development and innovation, in industry or academia, with a proven track record of independent research.
• Strong background in ML Framework libraries, including at least one deep learning framework (e.g., PyTorch, Tensorflow, JAX, etc.).
• Working knowledge of the model lifecycle process and an MLOps platform (e.g., Databricks, Sagemaker, AzureML, etc.).
• Outstanding oral and written communication skills.
  
  

Benefits: Korro offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance, a dependent care flexible spending account and a Company-funded health savings account and free parking.

Seniority level

• Seniority level

  Not Applicable

Employment type

• Employment type

  Full-time

Job function

• Job function

  Other

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