Scientist, Integrated Computational and Experimental Inflammation Discovery

Amgen SA; South San Francisco (CA); On-site; USD 150,000 - 190,000; Full time

Job summary

Amgen in South San Francisco, CA, seeks a Scientist to advance inflammation discovery, combining wet-lab experiments with AI-enabled omics analyses to identify targets, test hypotheses, and interpret complex datasets. You will connect experimental results with published literature and human genetics to prioritize therapeutic strategies in inflammation biology.

You'll manage defined project components with minimal supervision, develop science expertise, and communicate data-driven insights to

Qualifications

• Doctorate or equivalent in immunology, molecular biology, or biomedical sciences.
• Hands-on wet-lab experience in inflammation biology.
• Experience with multimodal omics data analysis and AI-enabled approaches.

Responsibilities

• Plan and coordinate project tasks for target identification and progression of inflammation discovery programs.
• Design, execute, analyze, and interpret bench/wet-lab studies to investigate disease mechanisms and test hypotheses.
• Apply computational, AI-enabled data-analytic approaches to generate mechanistic insights and refine experimental design.
• Integrate results with literature, human genetics, clinical observations, and internal/external datasets to inform project design.
• Develop and optimize solutions to technical problems within inflammation biology.
• Collaborate across functions and present data-driven insights in scientific forums.
• Organize, interpret, document, and present project data and recommendations.

Skills

Inflammation biology

Immunology basics

Spatial transcriptomics

Omics data analysis (Python/R)

Independent project work

Cross-functional collaboration

Education

Doctorate degree

Master’s degree

Bachelor’s degree

Job description

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission to serve patients living with serious illnesses drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas -Oncology, Inflammation, General Medicine, and Rare Disease- we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Scientist, Integrated Computational and Experimental Inflammation Discovery

What you will do

Let’s do this. Let’s change the world. In this vital role, you will contribute to Inflammation discovery programs by personally designing and executing wet-lab studies and applying computational and AI-enabled approaches to analyze and integrate omics data.

You will connect these insights with experimental findings to deepen our understanding of disease biology, prioritize therapeutic targets, and develop and test mechanistic hypotheses in the laboratory. Working with minimal supervision, you will manage defined program components, develop an area of scientific expertise, and communicate data-driven insights that help advance project decisions.

Key Responsibilities:

• Plan and coordinate defined project tasks and activities that support target identification, validation, and progression of Inflammation discovery programs.
• Design, execute, analyze, and interpret bench/wet lab studies to investigate disease mechanisms and test therapeutic hypotheses with scientific rigor and appropriate urgency.
• Apply computational, AI-enabled, and data-analytic approaches to generate mechanistic insights, refine experimental design, and integrate findings across data sources.
• Integrate experimental results with published literature, human genetics, clinical observations, and internal or external datasets to inform ongoing project design.
• Develop and optimize solutions to technical problems of advanced scope and complexity within an emerging area of expertise.
• Collaborate across functions and departments, contributing at the project-team level and building constructive relationships with wet-lab, computational, translational, and drug-discovery partners.
• Organize, interpret, document, and present project data and scientific recommendations within work groups, project teams, and internal scientific forums.
• Coach or guide others within the work group or project team where appropriate, and contribute to a collaborative culture of scientific curiosity, knowledge sharing, and operational excellence.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The researcher we seek is a Scientist with these qualifications.

Basic Qualifications:

Doctorate degree

OR

Master’s degree and 2 years of experience in Immunology, Cell Biology, Molecular Biology, Pharmacology, Biomedical Sciences, Computational Biology, Bioengineering

OR

Bachelor’s degree and 4 years of experience in Immunology, Cell Biology, Molecular Biology, Pharmacology, Biomedical Sciences, Computational Biology, Bioengineering

Preferred Qualifications:

• Demonstrated hands-on experience independently designing, executing, troubleshooting, and interpreting wet-lab experiments to investigate inflammation biology and validate therapeutic hypotheses.
• Strong grounding in inflammation and immunology, with the ability to translate computational insights into testable hypotheses and follow-up laboratory studies.
• Experience analyzing spatial transcriptomics data and/or integrating multimodal omics datasets to investigate disease mechanisms and inform target discovery.
• Hands-on proficiency in Python or R for omics data analysis and visualization, including the ability to critically evaluate analytical methods and outputs from AI-enabled tools and computational workflows.
• Ability to work independently and manage defined project components.
• Strong scientific communication and cross-functional collaboration skills.

What you can expect from us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.