Scientist III Cell Biology & Functional Genomics # 26-23630

US Tech Solutions; Ridgefield (CT); On-site; USD 90,000 - 120,000; Full time

Job summary

US Tech Solutions is seeking a scientist to support discovery research in cardiovascular-renal-metabolic diseases. The role involves hands-on mammalian cell culture, automated workflows, and NGS-based analyses, including iPSC-derived workflows and organoid-related work.

You will troubleshoot, document, and collaborate across biology, automation, and bioinformatics teams. The ideal candidate has 3–7+ years of experience, a Master’s or equivalent, and strong attention to detail as well as proven

Qualifications

• Master's degree required with 3+ years of relevant experience OR Bachelor's degree with 7+ years of relevant experience.
• Experience with mammalian cell culture and cell-based assays is essential.
• Hands-on NGS workflows including library prep, QC, and sequencing analysis are required.

Responsibilities

• Design, execute, and analyze cell-based experiments for target validation and discovery research.
• Operate and monitor automation workflows for cell-based and molecular assays; troubleshoot issues.
• Perform tissue, cell, and nuclei dissociation and execute RNA-seq workflows (bulk and single-cell).
• Carry out molecular biology techniques (DNA/RNA extraction, PCR/qPCR, quantification, Western blot).
• Maintain accurate records and comply with SOPs and safety requirements; collaborates across teams.

Skills

Mammalian cell culture

Cell-based assays

NGS workflows

Troubleshooting

Sample tracking

Collaborative work

Education

Master's degree in relevant field

Bachelor's degree in relevant field

Tools

Laboratory automation platforms

NGS library prep & sequencing

Job description

Job Description

• The successful candidate will support discovery research programs within Cardiovascular-Renal-Metabolic Diseases through hands-on operation of laboratory automation platforms, mammalian cell culture, cell-based assays, and functional genomics studies. The candidate will execute and monitor established automated cell culture and assay workflows and support automated iPSC-derived kidney organoid processes and next-generation sequencing (NGS)-related work, with platform- and workflow-specific training provided as needed.
• The role requires reliable execution of automation and NGS workflows. Success requires exceptional attention to detail, careful sample and reagent tracking, precise adherence to established protocols, and independent troubleshooting of routine experimental or platform issues.

Duration

02 Years Contract

Responsibilities

• Design, execute, and analyze cell-based experiments supporting target validation and discovery research, including routine mammalian cell culture, assay execution, image-based analysis, and iPSC-derived cell workflows.
• Operate and monitor established laboratory automation workflows for cell-based and molecular assays, troubleshoot routine issues, and elevate complex problems appropriately.
• Perform tissue, cell, and nuclei dissociation and execute NGS workflows for bulk RNA-seq, single-cell RNA-seq, single-nucleus RNA-seq, and related applications, including library preparation, quality control, quantification, normalization, sequencing setup, and sequencer operation.
• Perform routine molecular biology techniques, including DNA/RNA extraction, PCR and qPCR, nucleic acid and protein quantification, Western blotting, and basic sample preparation; analyze and interpret results, identify technical issues, and communicate findings and recommended follow-up clearly.
• Maintain accurate sample, reagent, consumable, experimental metadata, and electronic laboratory notebook records while complying with SOPs, safety requirements, company policies, and data integrity standards.
• Collaborate across cell biology, automation, genomics, and bioinformatics groups.

Experience

• 3-7+ years of relevant experience

Skillsets

• Strong hands-on experience with mammalian cell culture, cell biology, and cell-based assay execution.
• Hands-on NGS workflow experience, including tissue, cell, and/or nuclei dissociation, sequencing library preparation, quality control, and quantification for bulk RNA-seq, single-cell RNA-seq, single-nucleus RNA-seq, or related applications.
• Some hands-on experience with laboratory automation, automated instrumentation, or standardized high-throughput workflows, with the ability and interest to develop further expertise in operating and troubleshooting automated cell-based and molecular assays; automation programming is not required.
• Exceptional attention to detail and demonstrated ability to accurately execute lengthy, multi-step protocols while maintaining sample integrity, data quality, and complete documentation.
• Ability to independently troubleshoot routine experimental or operational issues, communicate clearly, and work effectively in a collaborative research environment.
• Experience running laboratory automation platforms for cell-based or molecular assays.
• Experience with sequencing run setup and sequencer operation. Instrument-specific operation can be trained when required.
• Experience with human induced pluripotent stem cell culture, differentiation, characterization, or iPSC-derived cell assays.
• Experience with kidney organoid culture systems.

Education

• Master's degree with 3+ years of relevant experience; or Bachelor's degree with 7+ years of relevant experience.

US Tech Solutions is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, colour, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.

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