Scientist II - Molecular and Proteomic Immunology

alleninstitute; Seattle (WA); On-site; USD 105,600 - 130,650; Full time

Benefits offered by this job

Medical benefits

401(k) plan

Paid time off

Job summary

The Allen Institute for Immunology is seeking a Scientist II – Molecular and Proteomic Immunology to design and apply molecular and proteomic methods that illuminate immune system interactions. You will develop assays and conduct in‑vitro and ex‑vivo immunology studies using cellular and animal models where applicable, analyzing data from multi-omics platforms.

A collaborative, creative researcher with a strong background in molecular biology and proteomics, plus experience in data analysis

Qualifications

• Ph.D. or equivalent in a life sciences discipline.
• 3+ years of postdoctoral experience.

Responsibilities

• Design and development of molecular and proteomic assays and technologies.
• Conduct in‑vitro and ex‑vivo immunologic studies using cells and tissues.
• Analyze and synthesize data from cellular, molecular and proteomic platforms.
• Collaborate with team to bring projects to completion on schedule.

Skills

Molecular biology

Proteomics

Data analysis

R/Python coding

Scientific communication

Education

Ph.D. in life sciences

3+ years postdoctoral experience

Tools

Xenium platform

10x Genomics platforms

CRISPR/Cas9

Job description

Scientist II – Molecular and Proteomic Immunology

The Allen Institute for Immunology is looking for an exceptional molecular immunologist (Scientist II) to join a team focused on using and developing molecular and/or proteomic approaches to comprehensively study the interactions of the immune system. Specific responsibilities will include the design and development of new assays, technologies, and in‑vitro and ex‑vivo immunologic studies along with the analysis and synthesis of data generated through our cellular, molecular and proteomic platforms or their derivatives. A flexible and creative mindset along with the ability to function in a team to bring projects to completion on a timeline is essential.

The successful candidate will have a strong background in molecular and/or proteomic methodologies along with prior neuroscience and/or immunology experience. Strongest consideration will be given to candidates with a proven track record in identifying and progressing novel hypotheses forward in discovery research and technology development. This position is expected to last through December 2028 based on business needs and funding.

Essential Functions

• Support the development and application of molecular and proteomic technologies to drive biological insight in the context of immunology. Examples include spatial and droplet‑based NGS platforms such as Xenium and 10x FLEX or REFLEX.
• Development of cellular engineering approaches for dissecting immune function. Examples could include molecular recorder systems and high‑throughput screens.
• Design, execute and analyze in‑vitro and ex‑vivo immunological studies utilizing cell lines, primary cells, and tissues to develop and test hypotheses, possibly including the utilization of genetic mouse models.
• Collaboration with a team to bring projects to completion on a timeline.

Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. This description reflects management’s assignment of essential functions; it does not proscribe or restrict the tasks that may be assigned.

Required Education and Experience

• Ph.D. or equivalent combination of degree and experience in a life sciences discipline.
• 3+ years of postdoctoral experience.

Preferred Education and Experience

• A strong background in molecular biology including NGS platforms.
• Experience in cellular immunology.
• Direct experience with advanced approaches in deconstructing immunologic mechanisms & testing hypotheses (e.g. targeted mutagenesis using CRISPR/Cas9, phenotypic screening, antibody‑based immune modulation, lentiviral work, cell culture, etc.).
• Proven success in troubleshooting and innovation on existing platforms, including publications and/or patents.
• Demonstrated ability to independently analyze data through coding languages (R, Python, Bash, version control).
• Exceptional oral and written communication skills and ability to effectively present complicated concepts internally and externally in a cross‑discipline environment.

Work Environment

• Working in a laboratory environment with potential exposure to lasers, biohazards.

Physical Demands

• Occasional lifting to 30 pounds.
• Fine‑motor movements in fingers/hands to operate computers and other office equipment; repetitive motion with lab equipment.
• Stooping, bending, crouching.

Position Type / Expected Hours of Work

• May need to work outside of standard working hours at times.
• This role is currently working onsite and is expected to work onsite for the majority of working hours. The primary work location for this role is 615 Westlake Ave N., with flexibility to work remotely on a limited basis. We are a Washington State employer; any remote work must be performed in Washington State.
• This position is expected to last through December 2028, based on business needs and funding.

Additional Eligibility Qualifications

• All employees who work with live animals must complete an Occupational Health medical history form and/or consultation with an Occupational Health Provider and receive clearance to work with animals. Depending on your health history and job responsibilities, an annual respiratory health screening and clearance to use a respirator may also be required.

Additional Comments

• Possible work visa sponsorship.
• Possible relocation assistance.

Annualized Salary Range

$105,600 - $130,650

* Final salary depends on required education for the role, experience, and level of skills relevant to the role, along with work location, where applicable.

Benefits

• Employees (and their families) are eligible to enroll in benefits per eligibility rules outlined in the Allen Institute’s Benefits Guide. These benefits include medical, dental, vision, and basic life insurance. Employees are also eligible to enroll in the Allen Institute’s 401(k) plan. Paid time off is also available as outlined in the Allen Institute’s Benefits Guide. Details on our benefits offering are located at https://alleninstitute.org/careers/benefits.

Equal Employment Opportunity Statement

It is the policy of the Allen Institute to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by federal, state or local law. In addition, the Allen Institute will provide reasonable accommodations for qualified individuals with disabilities.