Scientist II (Membrane Development)

Repligen; Marlborough (MA); On-site; USD 113,000 - 163,000; Full time

Benefits offered by this job

Paid time off

Health/dental/vision benefits

Retirement benefits

Flexible spending accounts

Job summary

Repligen in Marlborough, MA seeks a hands-on Scientist II to advance next-generation ultrafiltration and microfiltration membranes for bioprocessing. You will drive concept-to-commercialization work, own experimental programs, and collaborate with Manufacturing, Quality, Regulatory, and Supply Chain to deliver high-quality products.

The role emphasizes cross-functional teamwork, rigorous validation, and ownership of results in a fast-paced environment.

Qualifications

• PhD or MS/BS with extensive membrane development and process experience.
• Experience with polymeric membrane formation and separation technologies.
• Experience scaling up processes and transferring to manufacturing.
• Familiarity with Stage-Gate development, verification, and validation.
• Knowledge of quality/manufacturing tools and statistical analysis.

Responsibilities

• Develop ultrafiltration and microfiltration membranes and manufacturing processes from concept to commercialization.
• Lead process development, design verification, validation, scale-up, and technology transfer.
• Evaluate formulations and technologies to improve performance and manufacturability.
• Design and analyze lab and pilot-scale experiments to support project goals.
• Support validation using DFMEA, PFMEA, IQ/OQ/PQ, control plans, and process verification.
• Prepare technical documentation including reports, studies, tech transfer packages, and SOPs.

Skills

Membrane science

Process development

Scale-up & tech transfer

Quality & compliance

Cross-functional collaboration

Lab/pilot-scale experimentation

Education

Ph.D. in Chemical Engineering, Polymer Science, Materials Science, Chemistry, or related discipline

M.S. with 5+ years

B.S. with 8+ years

Tools

DFMEA

PFMEA

IQ/OQ/PQ

Statistical analysis

Process verification

Job description

This Scientist II will support the development and commercialization of next-generation ultrafiltration and microfiltration membrane technologies for bioprocessing applications. The position will contribute to projects from concept development through commercialization, including membrane design, process development, scale-up, verification and validation, technology transfer, and lifecycle support, with a focus on delivering high-quality solutions that meet customer and business needs.

The successful candidate will be a hands‑on scientist or engineer with strong expertise in membrane science and process development. This individual will work closely with cross‑functional teams including Manufacturing, Quality, Regulatory, Supply Chain, Marketing, and Commercial, bringing a collaborative and accountable approach to developing innovative products and manufacturing processes. The ideal candidate will take ownership of technical challenges, contribute ideas and perspectives, and work effectively across teams to drive results while maintaining a strong commitment to quality, integrity, and compliance.

This role is expected to model our Leadership Behaviors-Integrity & Compliance, Customer Focus, Collaboration, Courage, Team Empowerment, and Accountability & Results-in all aspects of work.

Responsibilities

• Develop ultrafiltration and microfiltration membranes and membrane manufacturing processes from concept through commercialization, with a focus on product performance, manufacturability, and customer needs.
• Execute new product development activities including process development, design verification, validation, scale-up, and technology transfer, taking ownership of deliverables and project outcomes.
• Evaluate membrane formulations, process improvements, and emerging technologies to enhance product performance and manufacturability, bringing forward new ideas and approaches to technical challenges.
• Design, execute, and analyze laboratory and pilot-scale experiments to address technical challenges, make informed decisions, and support project objectives.
• Support validation activities using quality and manufacturing tools including DFMEA, PFMEA, IQ/OQ/PQ, control plans, and process verification methodologies, maintaining a strong commitment to quality, integrity, and compliance.
• Prepare clear and accurate technical documentation, including development reports, characterization studies, validation reports, technology transfer packages, and SOPs.
• Maintain a highly hands‑on approach, spending significant time in the laboratory and pilot‑scale environment developing processes, operating equipment, and troubleshooting complex technical issues with a strong sense of ownership and accountability.
• Collaborate effectively with cross‑functional teams, sharing knowledge and perspectives and working toward common goals to advance development projects and commercialization efforts.

Qualifications

• Ph.D. in Chemical Engineering, Polymer Science, Materials Science, Chemistry, or related discipline with 2+ years of relevant industrial experience, or M.S. with 5+ years, or B.S. with 8+ years of relevant experience.
• Experience in polymeric membrane development, membrane formation processes, and membrane separation technologies.
• Experience supporting new product development projects, including process scale‑up and technology transfer to manufacturing.
• Familiarity with Stage-Gate product development processes, design verification and validation, and process validation activities.
• Working knowledge of quality and manufacturing tools such as DFMEA, PFMEA, IQ/OQ/PQ, process characterization, and statistical analysis.
• Strong experimental and troubleshooting skills with the ability to independently design and execute technical studies, make sound technical decisions, and take ownership of results.
• Highly hands‑on scientist/engineer who enjoys working in laboratory and pilot‑scale environments.
• Strong problem‑solving, communication, organizational, and teamwork skills, with the ability to collaborate effectively, share ideas, and contribute to team success.
• Demonstrated ability to manage multiple projects, prioritize effectively, and deliver results in a fast‑paced environment while maintaining high standards of quality and accountability.

What Repligen Offers

Our mission is to inspire advances in bioprocessing as a trusted partner in the production of biologic drugs that improve human health worldwide. Focused on cost and process efficiencies, we deliver innovative technologies and solutions that help set new standards in bioprocessing.

The estimated base salary range for this role, based in the United States of America is $113,000-$163,000. Compensation decisions are dependent on several factors including, but not limited to an individual's ,qualifications, location, internal equity, and alignment with market data. Additionally, employees are eligible to participate in one of our variable cash programs (bonus or commission) and eligible roles may receive equity as part of the compensation package.

We offer a wide range of benefits such as paid time off, health/dental/vision, retirement benefits and flexible spending accounts. All compensation and benefits information will be confirmed in writing at the time of offer.