Scientist II - LC-MS/MS Bioanalysis (Method Development)

Kcas, Llc; Kansas City (MO); Vor Ort; USD 85.000 - 110.000; Vollzeit

Benefits dieser Stelle

Stock ownership program

KCAS University

Company events: food trucks, family &\

Zusammenfassung

KCAS Bio, a fast-growing CRO in Kansas City, MO, seeks a Scientist II to advance bioanalytical studies using LC-MS/MS. You will handle sample prep, LC-MS/MS analysis, and data processing while supporting method development and troubleshooting under limited supervision.

Ideal candidates hold a 2–4 year background in LC-MS/MS, bioanalytical workflows, and chromatographic techniques, with experience in regulated environments. Opportunities for growth and involvement in senior-level updates await.

Qualifikationen

• Bachelor's or Master's in chemistry, Biochemistry or chemical/biochemical engineering, or related field with 2-4 years of LC-MS/MS experience.
• Hands-on experience with bioanalytical sample preparation, quantitative LC-MS/MS, and chromatography.
• Experience supporting method development, qualification, and troubleshooting; proteins/biomarkers experience preferred.
• Familiarity with reversed phase or HILIC chromatography and standard bioanalytical workflows.
• Experience in a regulated environment (GLP/GxP) preferred.

Aufgaben

• Execute study activities including sample preparation, LC-MS/MS analysis, and data processing with limited supervision.
• Support method development, qualification, and optimization activities.
• Troubleshoot technical issues and propose solutions with limited guidance.
• Analyze data and prepare summaries for senior scientists to aid in client updates.
• Ensure compliance of study activities with study protocols, SOPs and regulatory requirements.
• Communicate study progress and risks to senior staff.
• Provide informal guidance to junior staff as needed.

Kenntnisse

LC-MS/MS

bioanalytical sample preparation

chromatography

data processing

regulatory compliance (GLP/GxP)

Ausbildung

Bachelor's or Master's in Chemistry/Biochemistry/Engineering

Tools

LC-MS/MS instrument

Jobbeschreibung

Performing critical work that impacts our industry and our world's health while problem solving and innovating in the field - that is what Scientists at KCAS Bio get to do every day. If that gets you excited too, then maybe working as a Scientist at KCAS Bio is the role for you.

When you work as a Scientist II in the Mass Spec Bioanalysis Development group at KCAS, you get to further our mission by applying your knowledge of bioanalytical and scientific principles to independently execute study activities, from sample preparation and LC-MS/MS analysis through data processing, while supporting method development, qualification, and optimization. You will utilize your scientific foundation to assess data integrity, troubleshoot technical challenges, and deliver high-quality results with limited oversight.

Our Mass Spec Bioanalysis Development team uses LC-MS/MS (Liquid Chromatography-Tandem Mass Spectrometry) techniques and sophisticated sample preparation methods to meet bioanalytical needs for drug discovery, preclinical, and clinical studies, including the bioanalysis of drugs and metabolites, biomarkers, and active endogenous compounds in biological fluids and tissues.

In this role, we will rely on you to:

• Execute study activities including sample preparation (extractions, enrichments/affinity capture, digestions), LC-MS/MS analysis, and data processing with limited supervision
• Support method development, qualification, and optimization activities
• Troubleshoot technical issues and propose solutions with limited guidance
• Analyze data and prepare summaries for senior scientists to aid in client updates
• Ensure compliance of study activities with pertinent portions of study protocol, SOPs & regulatory requirements
• Communicate study progress and risks to senior staff
• Provide informal guidance to junior staff as needed
• Perform all aspects of the job in a way that supports company brand and supports company mission, vision, and values

To qualify specifically for this role, you will have:

• Bachelor's or master's in chemistry, Biochemistry or chemical/biochemical engineering, or related field with at least 2-4 years of experience with LC-MS/MS
• Hands-on experience with bioanalytical sample preparation, quantitative LC-MS/MS, and chromatography
• Experience supporting method development, qualification, and troubleshootingExperience with small molecule analysis; proteins, peptides, or biomarkers experience preferred
• Familiarity with reversed phase or HILIC chromatography and standard bioanalytical workflows
• Experience working in a regulated environment (GLP/GxP) preferred

Depending on your background and qualifications, we may consider hiring you for one of three levels of Scientist roles at KCAS Bio. This will be determined during the interview process.

(Please note this is a representative summary of responsibilities, not a comprehensive or exclusive list of the duties to be performed in any position. Employees must follow instructions and perform additional duties as requested.)

WHO YOU ARE

You will thrive at KCAS Bio if you enjoy a relational environment, are purpose- and values-driven, embrace constant development and supportive leadership, and enjoy being part of innovative work.

WHAT YOU'LL GET

Our benefits include, and extend beyond, the traditional package. At KCAS Bio, you will enjoy company sponsored events like food trucks, family days and spirit days.You will grow in your career with KCAS University.You will be able to connect with like-minded employees to further KCAS Bio's approach to key areas such as wellness, inclusion, and community outreach.You will engage as an owner in our stock ownership program. You will have access to the latest technology. And you will be able to invest in the community with paid time off to volunteer.

Learn more about the Benefits at KCAS Bio

WHO WE ARE

We are a fast-growing contract research organization (CRO) headquartered in Kansas City, pioneering the latest drug development in both human and animal health fields.Demand for our expertise is growing and so is our need for great people to work in nimble, empowered teams committed to one another’s growth. At KCAS Bio, we advance both great science AND great people.

Learn more about what it is like to work at KCAS Bio

KCAS Bio is proud to be an Equal Opportunity Employer. Among other things, we provide equal employment opportunities without regard to race, color, religion, national origin, ancestry, marital status, veteran status, age, disability, pregnancy, genetic information, sex, sexual orientation, gender identity, or any other legally protected category; we recruit qualified candidates without regard to citizenship status based on internal processes that enable us to hire the right candidates consistent with the appropriate U.S. Immigration framework; and (3) we work with and provide reasonable accommodations to individuals with disabilities and for sincerely held religious beliefs, observances, and practices. Anyone who needs reasonable accommodation may send an email to [e-mail] or call 913-248-3000 (for TTY assistance call 711) and ask for Human Resources.

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