Scientist I - Cell Engineering
Astellas Pharma
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Job summary
Astellas is seeking a Scientist I to contribute to the development and characterization of engineered cell therapeutics through design, execution, analysis of in vitro studies. The role supports platform and candidate advancement by generating high-quality data and collaborating across multidisciplinary research teams.
The successful candidate will participate in assay development, data interpretation, and scientific strategy, with opportunities to mentor junior scientists and engage in
Qualifications
- PhD/MS/BS with required years of experience as listed.
- Experience in cell biology, stem cell biology, cell therapy, gene therapy, or related areas.
- Hands-on cellular, molecular, and functional assay development and execution.
- Fluorescence/confocal microscopy, ICC/IHC, and image analysis experience.
- Strong experimental design, data analysis, and scientific problem-solving skills.
- Ability to independently plan, execute, and communicate research studies.
- Strong collaboration, organization, and communication skills.
Responsibilities
- Design, lead, and execute in vitro studies to evaluate engineered cell therapies.
- Develop, optimize, and implement cellular, molecular, and imaging-based assays.
- Independently analyze, interpret, and communicate complex datasets.
- Lead microscopy-based characterization and quantitative phenotyping.
- Collaborate with cross-functional teams and external partners.
- Contribute to experimental planning, candidate evaluation, and prioritization.
- Maintain high-quality documentation and communicate findings via reports and presentations.
- Mentor junior scientists and research associates.
Skills
Education
Tools
Job description
Astellas is a global life sciences company committed to turning innovative science into VALUE for patients. We provide transformative therapies in disease areas that include oncology, ophthalmology, urology, immunology and women's health. Through our research and development programs, we are pioneering new healthcare solutions for diseases with high unmet medical need. Learn more at Astellas.com.
Astellas is a global life sciences company committed to turning innovative science into VALUE for patients. We provide transformative therapies in disease areas that include oncology, ophthalmology, urology, immunology and women's health. Through our research and development programs, we are pioneering new healthcare solutions for diseases with high unmet medical need. Learn more at Astellas.com.
We're seeking passionate individuals who thrive in dynamic environments, embrace new ideas, and aren't afraid to take intelligent risks. People who act with unwavering integrity and are deeply committed to making a tangible impact.
The Scientist I, contributes to the development and characterization of engineered cell therapeutics through the design, execution, analysis, and interpretation of in vitro studies. The incumbent will support platform and candidate advancement by generating high-quality scientific data, developing and implementing characterization approaches, and collaborating across multidisciplinary research teams. Depending on experience level, the role may include increasing ownership of study design, assay development, data interpretation, and scientific strategy to support the advancement of engineered cell therapy programs.
- Design, lead, and execute in vitro studies to evaluate engineered cell therapies, including cell identity, functionality, potency, and mechanism-of-action characterization.
- Develop, optimize, and implement novel cellular, molecular, and imaging-based assays to support platform and candidate advancement.
- Independently analyze, interpret, and communicate complex datasets to drive scientific decisions and program strategy.
- Lead microscopy-based characterization efforts, including ICC/IHC, fluorescence and confocal imaging, image analysis, and quantitative phenotyping.
- Identify technical challenges, develop solutions, and drive continuous improvement in experimental approaches and characterization capabilities.
- Collaborate with cross-functional teams and external partners to advance research objectives and support translational studies.
- Contribute to experimental planning, candidate evaluation, and prioritization through scientific insight and critical thinking.
- Maintain high-quality documentation, communicate findings through presentations and reports, and contribute to a collaborative scientific environment.
- Mentor junior scientists and research associates through technical guidance, troubleshooting, and knowledge sharing
- PhD in Cell Biology, Molecular Biology, Pharmacology, Biomedical Sciences, or related field with 0-3 years relevant experience; OR
- MS with 5+ years relevant experience; OR
- BS with 8+ years relevant experience.
- Experience in cell biology, stem cell biology, cell therapy, gene therapy, or related research areas.
- Hands-on experience with cellular, molecular, and functional assay development and execution.
- Experience with fluorescence/confocal microscopy, ICC/IHC, and image analysis.
- Strong experimental design, data analysis, and scientific problem-solving skills.
- Ability to independently plan, execute, and communicate research studies.
- Strong collaboration, organization, and communication skills.
- Experience with retinal biology, ophthalmology, regenerative medicine, or stem cell-derived products.
- Experience with flow cytometry, ELISA/MSD, potency assays, or functional characterization methods.
- Experience in IHC/ICC, microscopy, image analysis
- Demonstrated scientific leadership through independent study ownership, mentorship, or technical leadership.
- This position is based in Westborough, MA and requires on-site work.
- The incumbent is expected to actively participate in experimental design, study execution, data analysis, and scientific discussions.
- The role involves collaboration with internal and external stakeholders in a highly collaborative research environment.
- Global collaboration: Become part of a connected global business of like-minded life science leaders, all dedicated to improving patients' lives worldwide.
- Real-world patient impact: Contribute to transformative therapies that reach patients around the world, knowing your work makes a difference every day.
- Relentless Innovation: Join a company at the forefront of scientific breakthroughs, where you'll have the opportunity to shape the future of healthcare.
- A Culture of Growth: Chart your own course within a supportive environment that values your contributions, champions your development, and empowers you to pursue your passions.
Innovation, Integrity and Impact sit at the heart of what we do.
We come together as One Astellas, working with courage and a sense of urgency. We are outcome focused and consistently take accountability for our personal contribution.
$94,570 - $135,100 (Final compensation will be determined based on a variety of factors, including but not limited to skills, experience and organizational equity considerations)
- Medical, Dental and Vision Insurance
- Generous Paid Time Off options, including Vacation and Sick time, plus national holidays including year-end shut down
- 401(k) match and annual company contribution
- Company paid life insurance
- Annual Corporate Bonus and Quarterly Sales Incentive for eligible positions
- Long Term Incentive Plan for eligible positions
- Company fleet vehicle for eligible positions
- Referral bonus program
Category Biology
Astellas is committed to equality of opportunity in all aspects of employment.
EOE including Disability/Protected Veterans
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