Scientist, Discovery Oncology

Merck & Co.; Boston (MA); On-site; USD 98,000 - 154,000; Full time

Benefits offered by this job

Medical, dental, vision insurance

401(k) retirement benefits

Paid holidays and vacation

Job summary

Merck & Co. is seeking a Scientist with oncology experience to join Discovery Oncology. You will design and execute lab experiments to validate novel targets for our early discovery pipeline, ensuring rigorous interpretation and clear communication of results.

The role requires mammalian cell culture, CRISPR/Cas9 perturbation, and molecular biology assays, with strong teamwork and documentation skills. Equal opportunity employer.

Qualifications

• BS/MS in a STEM field with relevant biology research experience in academia or industry.
• Expertise in mammalian cell culture, gene editing, and basic molecular biology assays is required.
• Strong data interpretation, troubleshooting, and ability to work in a team are essential.

Responsibilities

• Support target validation and mechanism of action in drug discovery efforts.
• Communicate data clearly to discovery teams and stakeholders.
• Collaborate across Discovery Oncology and related groups to advance projects.

Skills

Mammalian cell culture

CRISPR/Cas9 perturbation

Transfection techniques

PCR/qRT-PCR

Western blot

Proliferation/cytotoxicity/apoptosis

Data interpretation

Strong communication

Antibody therapeutics

Biologics

Cancer cell biology

Oncology

Education

BS in cancer/immunology/biotechnology/biology/molecular biology/biochemistry/oncology/genetics/genomics or related STEM field

MS degree with 0+ years' experience

Job description

Job Description

Job Summary:

We are seeking a highly motivated and skilled Scientist with a background in Oncology to join a cross-functional team within Discovery Oncology. Primary responsibilities will include designing and executing experiments in the laboratory to validate novel targets for our early discovery pipeline and to support drug discovery efforts. An ability to communicate clearly, collaborate effectively with colleagues in the discovery group as well as scientists from different disciplines and a sense of scientific rigor will be essential.

Responsibilities:

• Support target validation, mechanism of action and drug discovery efforts
• Ensure data generated is communicated in a concise, easy to understand manner to the appropriate teams and stakeholders.
• Collaborate with colleagues from Discovery Oncology, in vivo pharmacology, Genome and Biomarker Sciences, Chemical Biology, and Quantitative Biosciences to support drug discovery efforts.

Required Education and Experience:

• The candidate will have a BS in the area of cancer, immunology, biotechnology, biology, molecular biology, biochemistry, oncology, genetics/genomics, or related STEM field with 3 years' experience or a MS degree with 0+ years' experience in an academic or industry setting.

Required Skills:

• Expertise in mammalian cell culture
• Expertise in transfection and CRISPR/Cas9 genetic perturbation
• Expertise in cell and molecular biology techniques including PCR, qRT-PCR, western blot, and proliferation/cytotoxicity/apoptosis assays
• Demonstrated ability to work independently to design experiments, interpret data, troubleshoot, and suggest next steps
• Candidate should be a strong team player with excellent oral and written communication skills and with a demonstrated ability to work collaboratively and thrive in a team environment
• Excellent organization and ability to contribute to multiple projects

Preferred Skills:

• Previous experience working with protein-based therapeutics in an industry setting

Required Skills (Additional):

• Assay Development
• Biology
• Cell Biology
• Cell Culture Techniques
• CRISPR-Cas System
• Data AnalysisDrug Discovery Research
• In Vitro Assays
• Mammalian Cell Culture
• Mechanism of Action
• Molecular Biology
• Target Discovery
• Target Validation

Preferred Skills (Additional):

• Antibody Therapeutics
• Biologics
• Cancer Cell Biology
• Oncology

US and Puerto Rico Residents Only:

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities.

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics.--As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities.- For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

EEOC Know Your Rights

EEOC GINA Supplement

We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively.

Learn more about your rights, including under California, Colorado and other US State Acts

Salary Range:

$98,000.00 - $154,300.00

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee's position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

Benefits:

• Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits .

San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

Los Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles' Fair Chance Initiative for Hiring Ordinance

Search Firm Representatives Please Read Carefully-

Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. -No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Employee Status:

Regular

Relocation:

No relocation

VISA Sponsorship:

No

Travel Requirements:

No Travel Required

Flexible Work Arrangements:

Not Applicable

Shift:

Not Indicated

Valid Driving License:

No

Hazardous Material(s):

OEB4, OEB5, standard lab reagents