Scientist- Biologics Analytical Sciences

Zoetis; Kalamazoo (MI); In loco; USD 90.000 - 120.000; Tempo pieno

Descrizione del lavoro

Zoetis in Kalamazoo, MI is seeking a Scientist/Sr. Scientist in Biologics Analytical Sciences to characterize biological molecules and advance analytical methods for biopharmaceutical products.

The role involves collaboration with scientists to develop high-throughput techniques and to communicate results to cross-functional teams. Minimum qualifications include BS/MS in chemistry/biochemistry with industry experience and strong skills in HPLC, CE, and MS.

Competenze

• BS or MS in Chemistry, Biochemistry, Biology, or related field with industry experience (BS 4+ yrs, MS 2+ yrs).
• Prefer experience in animal health biopharmaceutical industry.
• Experience with HPLC, capillary electrophoresis for protein analysis.
• Experience developing and validating biopharmaceutical analytical methods.
• Ability to communicate results to technical and non-technical stakeholders.

Mansioni

• Characterize biological molecules, identify degradation pathways, and define critical quality attributes.
• Contribute to analytical method development, qualification, validation and transfer.
• Maintain familiarity with literature and apply new knowledge to projects.
• Present complex concepts to interdisciplinary teams via oral/written reports.
• Develop high-throughput and automated sample preparation methods.
• Document results in electronic notebooks and technical reports.

Conoscenze

HPLC

Capillary electrophoresis

Mass spectrometry

Biopharmaceutical analysis

Formazione

BS in Chemistry

MS in Biochemistry

Strumenti

Empower

ChemStation

Descrizione del lavoro

Scientist/ Sr. Scientist - Biologics Analytical Sciences

Zoetis is a global animal health company dedicated to supporting customers and their businesses. Building on 60 years of experience, we deliver quality medicines, biopharmaceuticals and vaccines, complemented by diagnostic products and genetic tests and supported by a range of services. We are working every day to better understand and address the real-world challenges faced by those who raise and care for animals in ways they find truly relevant.

Zoetis discovers, develops and manufactures diverse portfolio of animal health medicines, biopharmaceuticals and vaccines designed to meet the real-world needs of veterinarians and the livestock farmers and companion animal owners they support. Zoetis has the first monoclonal antibody therapy for treating atopic dermatitis in dogs. We are currently seeking to fill new positions to support our growing biopharmaceutical portfolio.

Zoetis Veterinary Medicine Research and Development, Biologics Analytical Sciences in Kalamazoo, MI is seeking an analytical scientist at the Scientist level.

Responsibilities include, but are not limited to, the following:

• Characterization of biological molecules, identify degradation pathways, and define critical quality attributes. Contribute to analytical method development, qualification, validation, and transfer activities. Primary techniques are High performance liquid chromatography (HPLC), capillary electrophoresis, spectroscopy and mass spectrometry.
• Maintain familiarity with scientific literature and apply new knowledge appropriately to projects.
• Convey complex and nuanced concepts to interdisciplinary teams through oral and written presentations, and reports.
• Work in collaboration with other scientists to advance the development of state-of-the-art techniques to characterize biopharmaceutical products, assays, and tools. Develop high-throughput and/or automated methodologies for sample preparation.
• Develop creative solutions to moderately complex problems.
• Document and communicate results in electronic laboratory notebooks, technical reports, and oral presentations.

Minimum Qualifications:

• BS or MS in Chemistry, Biochemistry, Biology, or other related discipline, with industry experience (BS w/ 4+ years, MS w/ 2+ years), preferably in the animal health biopharmaceutical industry.
• Motivated self-starter with excellent communication (oral and written), interpersonal, and organizational skills.
• Experience in separation technologies including multiple modes for HPLC and capillary electrophoresis (e.g., SEC, RP-HPLC, IEX, icIEF, CE-SDS) for the analysis of complex proteins.
• Experience in developing, and validating biopharmaceutical analytical methods, including liquid chromatography (UHPLC), electrophoretic separations, and glycoprotein analysis.
• Candidate demonstrates a breadth of diverse experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.
• Prepare comprehensive analytical reports and presentations, conveying findings to both technical and non-technical stakeholders.
• Strong problem-solving skills and a proactive attitude toward process improvement

Preferred Qualifications:

• More than 4 years of industry experience in developing, validating and transferring biopharmaceutical analytical methods
• Strong understanding of protein structure, post-translational modifications (including glycans) and potential sequence liabilities (including oxidation, deamidation, and clipping)
• Familiarity with biopharmaceutical manufacturing processes, including cell culture, purification, and formulation.
• Proficiency in Empower and Chemstation chromatographic software.
• Skills and experience in experimental design, technical problem solving and continuous improvement
• Experience and understanding of mass spec analysis of biological products using LC-MS
• Familiarity in plate-based assays such as ELISA

About Zoetis
At Zoetis, our purpose is to nurture the world and humankind by advancing care for animals. As a Fortune 500 company and the world leader in animal health, we discover, develop, manufacture and commercialize vaccines, medicines, diagnostics and other technologies for companion animals and livestock. We know our people drive our success. Our award-winning culture, built around our Core Beliefs, focuses on our colleagues' careers, connection and support. We offer competitive healthcare and retirement savings benefits, along with an array of benefits, policies and programs to support employee well-being in every sense, from health and financial wellness to family and lifestyle resources.