Scientific Leader, Discovery Integration Sciences

GlaxoSmithKline; Upper Providence (Delaware County); Hybrid; USD 150,000 - 190,000; Full time

Job summary

GlaxoSmithKline (GSK) invites a Scientific Leader, Discovery Integration Sciences to help build the world’s leading LIAL platform. You will steer cross‑functional teams of scientists and engineers to design, implement, and operate integrated discovery systems that fuse computational intelligence with automated lab workflows.

You will mentor early career researchers, translate scientific needs into robust system architectures, and push AI-driven data workflows across cloud environments to

Qualifications

• PhD or MS with 3+ years in a scientific field with computational work.
• Minimum 5 years leading matrix teams across science and tech to deliver software in evolving environments.
• Minimum 5 years Python (or R) programming experience.
• Experience with modern software development tools (OOP, git/GitHub, CI/CD).
• At least 3 years cloud experience (GCP, AWS, Azure, Kubernetes) for data workflows and lab automation.

Responsibilities

• Collaborate across R&D and Tech to design and deploy LIAL Systems.
• Translate science requirements into system designs and enable platform capabilities.
• Lead cross-functional teams, mentoring others.
• Apply new methods and data sources to accelerate autonomous science using AI.
• Prepare presentations and decision materials for project forums.

Skills

Python programming

Leadership

Cross‑functional teams

AI/ML concepts

Data analysis

Education

PhD or MS in a relevant scientific discipline

Tools

Git/GitHub

CI/CD

Nextflow

Airflow

Kubernetes

Job description

Scientific Leader, Discovery Integration Sciences

Business Introduction: At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting‑edge technology to transform people's lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients' needs and have the highest probability of success. We're uniting science, technology, and talent to get ahead of disease together.

Find out more: Our approach to R&D

Description

For UK candidates seeking to be located at our Stevenage site, this role will temporarily be based at Stevenage. However, the Company plans to relocate its offices to Cambridge and Ware. The location of this role will therefore subsequently change to Cambridge or Ware in accordance with timelines to be set by the Company. The relocation is currently proposed to take effect by early 2029.

Job Title

Scientific Leader, Discovery Integration Sciences

Job Purpose

Do you share a desire to advance scientific knowledge and capitalise on the revolution in data, automation and predictive sciences to deliver measurable impacts on the success and progression of GSK's medicine discovery portfolio?

The Data, Automation and Predictive Sciences (DAPS) function of GSK Research Technologies focuses on large-scale data generation, curation, analysis and prediction to deliver higher PTRS (Probability of Technical and Regulatory Success) assets and unlock upper quartile ambitions. Within DAPS, the Discovery Integration Sciences team is driving efforts across Research to build the world's most efficient and effective biopharma discovery platform at GSK by building and deploying innovative Lab-in-an-Automated-Loop (LIAL) Systems that integrate computational intelligence with physical laboratory experimentation in adaptive learning cycles. Each LIAL System will deliver a domain leading scientific discovery solution that leverages and extends state-of-the-art scientific methods by engineering technologies to create integrated discovery systems that empower GSK research scientists with the latest tools. LIAL Systems will therefore be physical instantiations of GSK's mission to unite science, technology and talent to get ahead of disease together.

As a Scientific Leader in the Discovery Integration Sciences team you will work and lead across scientific and technical disciplines in cross‑functional teams designing, delivering and operating the System‑of‑LIAL‑Systems that will power GSK's Research activities and the underlying LIAL Platform that provides the abstracted blueprint and technical services for building and operating LIAL Systems at scale.

Key Responsibilities

• Collaboratively and iteratively develop and deploy LIAL Systems by partnering with scientists and technical teams across R&D and Tech to (re)design experimental processes for LIAL enablement and implement as integrated systems.

• Translate scientific requirements into system designs and enabling platform capabilities and conversely articulate platform capabilities as system enablers of improvements to scientific processes.

• Foster inclusive high‑quality scientific and technical collaboration by working within and leading cross‑functional matrix teams which mentoring and supporting others.

• Introduce and apply new methods, tools, and data sources to drive innovation and continuously improve the speed, quality, and predictability of autonomous science using AI and Agents.

• Prepare clear presentations and reports for project teams and decision‑making forums.

Basic Qualifications

• Doctoral degree (PhD or equivalent) or MS +3 years professional experience in a relevant scientific discipline with a significant computational component.

• Minimum of 5 years professional experience working in and leading matrix teams across scientific and technical disciplines to deliver software projects integrating wet lab and dry lab capabilities in a continuously evolving landscape.

• Minimum of 5 years of experience programming and software engineering using Python (preferred) and/or R.

• Experience with modern software development tools / ways of working (e.g. object‑oriented programming, git/GitHub, CI/CD).

• Minimum of 3 years of experience using cloud technologies (e.g. GCP, AWS, Azure, Kubernetes) to build and deploy data workflow automation (e.g. Nextflow, Airflow), digital lab automation (e.g. orchestration, scheduling) and/or integrated ("lab-in-the-loop") solutions.

Preferred Qualifications

• Proven track record of designing, developing and deploying complex scientific software solutions with clear impact.

• Strong leadership skills demonstrated by leading projects, influencing decisions and communicating with multidisciplinary teams and senior stakeholders in a cross‑functional setting.

• Demonstrated learning agility (e.g. working across modality or domains) and scientific curiosity while maintaining focus on driving impact in the face of ambiguity.

• Experience mentoring or line‑managing early‑career scientists with a demonstrated focus on driving performance, skills, capability and career development to grow and improve the team.

Work Arrangements

The role is hybrid, requiring on‑site 2-3 days per week. Remote or fully home‑working arrangements are not available for this role.

Skills

Artificial Intelligence (AI), Computational Sciences, Computer Programming, Data Analysis, Data Management, Data Modeling, Data Science, Predictive Modeling, Statistical Models

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases - to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we're committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

If you require an accommodation or other assistance to apply for a job at GSK, please contact the appropriate Recruitment Staff by emailing us at - [e-mail].

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

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