Researcher — CRISPR & Translational Genomics

University of Alabama at Birmingham; Birmingham (AL); Hybrid; USD 50,000 - 81,000; Full time

Job summary

The University of Alabama at Birmingham invites applications for a Researcher in the Pulmonary/Allergy/Critical Care department. The role focuses on genome engineering and transgenic animal model development, including molecular and cellular analyses to advance translational medicine.

Responsibilities include CRISPR/Cas9 genome editing, data interpretation, grant support, and collaboration across disciplines in a well-funded, multi-PI environment.

Qualifications

• Master's degree or higher in a related field is required. Work experience may not substitute for education.
• Bachelor's degree with 2+ years related experience or Associate's with 4+ years, or HS diploma with 6+ years experience is acceptable.

Responsibilities

• Genotype and characterize genetically modified animal models.
• Manage genotyping of the transgenic colony by an external company.
• Perform molecular analyses including PCR, RT-PCR, qPCR assays.
• Conduct protein studies using Western blotting and ELISA.
• Establish and maintain mammalian cell lines and primary cell cultures.
• Perform confocal imaging and data interpretation.
• Analyze experimental data using statistical software and prepare research reports.
• Manage laboratory resources, equipment and supplies, train and mentor junior staff and students.
• Collaborate with investigators to advance basic and translational research projects.

Skills

CRISPR/Cas9 genome editing

Genotype & phenotypic analysis

Data analysis (statistics)

Education

Master's degree in related field

Bachelor's degree with 2 years related experience

Associate's degree with 4 years related experience

High School diploma or GED with 6 years related experience

Tools

PCR

RT-PCR

qPCR

Western blotting

ELISA

Confocal imaging

Job description

The University of Alabama at Birmingham invites applications for a Researcher in the Pulmonary/Allergy/Critical Care department. The role focuses on genome engineering and transgenic animal model development, including molecular and cellular analyses to advance translational medicine.

Responsibilities include CRISPR/Cas9 genome editing, data interpretation, grant support, and collaboration across disciplines in a well-funded, multi-PI environment.