Research Technician II - PSC Core Facility

Children's Hospital of Philadelphia; Philadelphia (Philadelphia County); On-site; USD 44,000 - 55,000; Full time

Job summary

Children's Hospital of Philadelphia (CHOP) invites you to join our Pluripotent Stem Cell Core as a Research Technician II. This entry-level role supports human pluripotent stem cell culture, iPSC workflows, CRISPR-based editing, and rigorous documentation in a fast-paced, collaborative environment.

You will maintain PSC/iPSC cultures, assist differentiation workflows, contribute to gene editing tasks, and help with sample tracking, data organization, and compliance with SOPs.

Qualifications

• High School Diploma or GED required.
• Associate's or Bachelor's degree preferred.
• Experience in a research lab environment is preferred.

Responsibilities

• Maintain and expand PSC/iPSC cultures and workflows.
• Support differentiation workflows and gene editing tasks.
• Ensure accurate documentation and data organization.
• Follow SOPs and assist in protocol optimization.
• Maintain inventory and support supply management.

Skills

Lab procedures

Documentation

Organizational skills

Communication

Data analysis

Education

High School Diploma / GED

Associate's Degree

Bachelor's Degree

Tools

CRISPR

PSC/iPSC culture

Job description

SHIFT: Day (United States of America)

Seeking Breakthrough Makers

Children's Hospital of Philadelphia (CHOP) offers countless ways to change lives. Our diverse community of more than 20,000 Breakthrough Makers will inspire you to pursue passions, develop expertise, and drive innovation.

At CHOP, your experience is valued; your voice is heard; and your contributions make a difference for patients and families. Join us as we build on our promise to advance pediatric care-and your career.

CHOP does not discriminate on the basis of race, color, sex, national origin, religion, or any other legally protected categories in any employment, training, or vendor decisions or programs. CHOP recognizes the critical importance of a workforce rich in varied backgrounds and experiences and engages in ongoing efforts to achieve that through equally varied and non-discriminatory means.

A Brief Overview

This entry-level research technical role participates in a planned research projects by performing research protocols, experimental procedures and other laboratory tasks under direct supervision. May occasionally exercise minimal discretion and judgment in execution and interpretation of experiments, and of data derived.

The Pluripotent Stem Cell (PSC) Core within the Center for Cellular and Molecular Therapeutics at The Children's Hospital of Philadelphia (CHOP) is seeking a highly motivated Research Technician II. This position provides hands‑on support for core services involving human pluripotent stem cells, including iPSC culture, differentiation workflows, and CRISPR‑based gene editing, in a fast‑paced, highly collaborative environment. The successful candidate will be exceptionally detail‑oriented, organized, and committed to thorough documentation to support reproducibility and core operations.

This role will focus on routine maintenance and expansion of PSC/iPSC lines, execution of differentiation workflows as needed, and participation in CRISPR gene editing and downstream screening/validation support. Strong note‑taking, sample tracking, and organizational skills are essential.

Core Website: https://www.research.chop.edu/human-pluripotent-stem-cell-core

What you will do

• Maintain and expand PSC/iPSC cultures (routine culture, passaging, cryopreservation, thawing, QC support)
• Perform differentiation workflows as needed (neural lineage experience is a plus)
• Execute CRISPR gene editing-related tasks (e.g., preparation, delivery support, and coordination of downstream clone screening/validation workflows as appropriate for the core)
• Follow established SOPs and contribute to protocol optimization when appropriate
• Prepare reagents, maintain inventory, and support ordering/supply management
• Maintain shared lab/core spaces, equipment logs, and general lab organization
• Communicate effectively with core staff, investigators, and trainees; support core users as needed
• Maintain excellent documentation: clear experimental notes, sample labeling and tracking, data organization, and accurate records in electronic and/or paper notebooks (per core requirements)
• Performs routine tests / experiments under the direction of principal investigator, supervisor or other designee
• Performs research procedures on experimental samples as directed
• Records and checks experiments/ results for completeness and accuracy
• Performs calculations and maintains appropriate log and lab notebooks
• Performs tasks that require familiarity with fundamental techniques and lab equipment
• May assist with planning specific research protocols and procedures
• Maintains office, lab area, solutions, reagents, supplies and equipment, disposes of specimens, media and other materials (using appropriate procedures)
• Assists in care and maintenance of lab equipment
• May coordinate schedules of tests and procedures
• Attends courses, seminars, and lab meetings to expand knowledge of research and laboratory techniques
• Records results, organizes data and maintains lab notebook in an organized manner
• Compiles and helps analyze data, prepares charts, graphs, and results of studies as directed
• Conducts literary searches as directed

Education Qualifications

• High School Diploma / GED - Required
• Associate's Degree - Preferred
• Bachelor's Degree - Preferred

Experience Qualifications

• At least one (1) year of related classroom experience or successful completion of a technical training program (eg. Wistar, WPSI) and research laboratory experience - Required
• At least two (2) years of related classroom experience or successful completion of a technical training program (eg. Wistar, WPSI) and research laboratory experience - Preferred

Skills and Abilities

• Intermediate understanding of lab procedures, protocols, and equipment.
• Basic exposure to lab specific experiments / techniques and scientific analysis
• Excellent verbal and written communications skills
• Excellent organizational skills
• Solid critical thinking / problem-solving skills
• Solid analytical skills

To carry out its mission, CHOP is committed to supporting the health of our patients, families, workforce, and global community. As a condition of employment, CHOP employees who work in patient care buildings or who have patient facing responsibilities must receive an annual influenza vaccine. Learn more.

EEO / VEVRAA Federal Contractor | Tobacco Statement

SALARY RANGE

$43,900.00 - $54,800.00 Annually

Salary ranges are shown for full-time jobs. If you're working part-time, your pay will be adjusted accordingly.

At CHOP, we are committed to fair and transparent pay practices. Factors such as skills and experience could result in an offer above the salary range noted in this job posting.