Research Scientist, Sr

University of Massachusetts Medical School; Worcester (MA); On-site; USD 90,000 - 130,000; Full time

Job summary

University of Massachusetts Medical School seeks a Senior Research Scientist to conduct complex laboratory research under the PI, performing recombinant DNA and molecular biology techniques, data analysis, and manuscript preparation. The role includes supervising staff, managing supplies, and ensuring safety and regulatory compliance in a wet lab environment.

The candidate will design and execute experiments, analyze results, and contribute to grant applications, while staying current with

Qualifications

• Bachelor's degree in Biological Science or equivalent.
• 7 years of research experience.
• Familiarity with general laboratory procedures.
• Expertise in specific procedures and instrumentation for research programs.
• Current knowledge of pertinent literature.
• Strong oral and written communication and presentation skills.
• Ability to travel to off-site locations.

Responsibilities

• Design and implement experiments for ongoing projects in consultation with the PI.
• Organize and analyze data from research projects.
• Write manuscripts and grant applications.
• Lead and manage laboratory projects and investigations.
• Oversee data acquisition, analysis, and presentation of results.
• Train and supervise junior lab personnel and technicians.
• Prepare data for publication and for grant proposals.
• Assist in general laboratory operations and regulatory obligations.
• Participate in regular lab meetings and literature discussions.

Skills

Oral and written communication

Supervision

Travel readiness

Education

Bachelor's degree in Biological Science

Tools

Western blotting

qPCR

RT-PCR

PCR

Cell culture

Job description

Overview

GENERAL SUMMARY OF POSITION:

Under the general direction of the Principle Investigator, the Senior Research Scientist performs a variety of complex research experiments laboratory research on topics pertinent to the interests of the research programs of the laboratory.

Work under limited supervision in carrying out complex research assignments, performance of experiments and recording of results: creation, amplification, maintenance and quality control of recombinant adenovirus and adeno-associated virus vector stocks, tissue histology, Western blots, qPCR, RT-PCR, PCR, work with recombinant DNA including mutagenesis and recording of experimental results, growth and maintenance of cell cultures, preparation of reagents for experiments, may also assist in procedures on experimental animals. Be proficient and independent in molecular methods and teach methods to technicians and trainees.

Working with the P.I. and other lab members to interpret experiments. Utilize new and innovative research techniques, and adapting new assays for use in the lab, evaluate the adequacy of techniques and test new procedures.

Perform lab management duties including ordering and maintaining supplies and equipment, maintaining records of grant expenditures and purchases, developing and implementing institution-required safety plans, other regulatory obligations of the laboratory and other necessary paperwork, and supervision of other lab technicians.

Responsibilities

MAJOR RESPONSIBILITIES:

• Design and implement experiments designed to further ongoing research projects, in consultation with the principal investigator.
• Organize and analyze data acquired in the course of research projects.
• Write manuscripts and grant applications.
• Design and implement research projects in the laboratory.
• Responsible for data acquisition, data analysis, and presentation of research results.
• Train and supervise junior lab personnel, ensuring staff is trained in current methodology and safety procedures in the laboratory.
• Prepare and present data for publication in public forums.
• Assist in the preparation of grant applications and other research proposals.
• Provide assistance in the general operation of the laboratory.
• Participate regularly in laboratory meetings.
• Stay current with the literature and regularly lead discussions of new reports pertinent to ongoing and proposed projects.
• Perform other duties as required.

Qualifications

REQUIRED QUALIFICATIONS:

• Bachelor’s degree in a Biological Science, or equivalent degree.
• 7 years of research experience.
• Familiarity with general laboratory procedures.
• Expertise in specific procedures and instrumentation necessary to complete specific research programs.
• Current knowledge of pertinent literature.
• Oral and written communication and presentation skills.
• Ability to travel to off-site locations.

SUPERVISION RECEIVED:

Under the general direction of the Principle Investigator.

SUPERVISION EXERCISED:

Supervises and trains new laboratory personnel and junior members of the laboratory.

ENVIRONMENTAL WORKING CONDITIONS:

Wet chemistry laboratory, and may require appropriate contact with biohazards, radionuclides, toxins, animals, and human specimens.