Research Scientist - In vitro DMPK

Qps-Holdings,-LL; Newark (DE); On-site; USD 80,000 - 92,000; Full time

Job summary

QPS, LLC in Newark, Delaware seeks a Research Scientist - Invitro with an advanced degree in analytical chemistry, biochemistry or pharmacology. The role focuses on independent study design, in vitro metabolism using S9/microsomes, cell culture, and enzyme induction with human hepatocytes.

The candidate will manage data analysis, prepare reports, supervise junior staff, and contribute to publications while working 100% in-office at the Newark facility.

Qualifications

• Advanced degree in Analytical Chemistry, Biochemistry, Pharmacology, or related discipline.
• Ph.D. or Master’s degree with 6+ years relevant experience.
• Understanding of experimental design and data analysis software.
• Proven ability to work effectively in a team.
• Excellent oral and written communication skills.

Responsibilities

• Independently understand, recognize and initiate/prepare study protocols and reports.
• Independently perform in vitro metabolism studies using S9, microsomes, cytosol and cDNA expressed enzymes.
• Perform cell culture and maintain cell lines, prepare cells and conduct metabolic and transport studies.
• Conduct enzyme induction studies using fresh/cryopreserved human hepatocytes.
• Isolate and purify mRNA, quantify by qRT-PCR and determine induction status.
• Prepare data summaries, interpret results and report findings.

Skills

In vitro metabolism

Cell culture

qRT-PCR

Data interpretation

Team collaboration

Excellent communication

Education

Ph.D. degree

Master’s degree with ≥ 6 years relevant experience

Job description

Research Scientist - Invitro

Full Time Regular Sr Professional-Lab Newark, DE, US

3 days ago Requisition ID: 3208

Salary Range: $80,000.00 To $92,000.00 Annually

Do you want to be part of an organization that is making a difference in the lives of millions of people worldwide? If so, we want to hear from you! As a Research Scientist, you will be a key contributor in QPS’ Distribution, Metabolism, Pharmacokinetics (DMPK) department. As the Principal Investigator, incumbent will fill the role of Technical Leader, and be responsible for completing portions of/entire, projects, and providing quality and timely results, as well as collaborating and communicating with Clients, QPS management, and external resources.

Since its inception, QPS has been assisting pharmaceutical, biotechnology and medical device companies with their drug development efforts by providing a full range of Neuropharmacology, DMPK, Toxicology, Bioanalysis, Translational Medicine, Early Phase Clinical and Phase II – IV Clinical Research services. To meet the needs of our clients, we strive to employ talented, caring and committed individuals who will work collaboratively towards achieving our mission of improving human health and the quality of life.

Team members enjoy challenging and rewarding work, and are encouraged to achieve their best. Underpinning the operation is a culture that values diversity, innovation, accountability, teamwork and a friendly atmosphere where performance is recognized and rewarded. We provide unique company benefits, training, and advancement opportunities. Most importantly, we value each of our team members as employees and as individuals.

If this sounds like your ideal work environment, then we would love to speak with you, so apply today!

Please visit our website (www.qps.com ) for more information and to see all current openings.

The Job

• Independently understand, recognize and initiate/prepare study protocols and reports.
• Independently perform in vitro metabolism studies using S9, microsomes, cytosol and cDNA expressed enzymes.
• Perform cell culture and maintain cell lines, prepare cells and conduct the metabolic as well as drug transport studies.
• Conduct enzyme induction studies using fresh/cryopreserved human hepatocytes.
• Isolate and purify mRNA, quantify mRNA by qRT-PCR and determine the enzyme induction status.
• Simultaneously handle lab work as well as routine projects.
• Prepare data summaries and data interpretation.
• Evaluate significance of data and report findings.
• Supervise, train and/or mentor junior scientists.
• Prepare materials for presentations and publications.

Work Location

• This job will be 100% QPS-office/facility based

Requirements

• The successful candidate will hold an advanced degree in Analytical Chemistry, Biochemistry, Pharmacology, or related scientific discipline as follows:
  • Ph.D. degree
  • Master’s degree with ≥ 6 years relevant experience
• Understanding of experimental design and planning associated with assigned area, as well as data collection and analysis software.
• Proven ability to successfully work in a team environment.
• Excellent oral and written communication skills.
• Ability to make independent decisions.

Why You Should Apply

• Great learning opportunities, especially for those new to the field. Our seasoned professionals are here to support and work with you to explore your learning potential and career goals.
• Structured Career Ladders that provide excellent growth based on your personal aspirations.
• Bonuses and merit increases are a part of the QPS total rewards approach and are linked to individual, team and company performance.
• Solid Benefits package, including Company-matched 401(k), and Company-sponsored Group Life/AD&D and Short and Long-term Disability Insurance
• Park-like setting in Newark, Delaware
• Internal committees designed with the needs and enjoyment of QPS employees in mind.

QPS, LLC is an Equal Employment Opportunity/Affirmative Action Employer. In accordance with federal, state, and local laws, we recruit, hire, promote and evaluate all personnel without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, citizenship status, physical disability, protected veteran status, or any other characteristic protected by law. Job applicants and present employees are evaluated solely on ability, experience, and the requirements of the job. In addition, QPS, LLC is a federal contractor and desires priority referrals of protected veterans.