Research Scientist, Cellular Physiology

Nudge; San Francisco (CA); On-site; USD 90,000 - 130,000; Full time

Job summary

Nudge is seeking a senior researcher to advance ultrasound technology for neuromodulation. The candidate will develop experimental methods, design in-vitro studies, and translate findings to human applications. A PhD and 5+ years of experience in a related science or engineering field are required, along with expertise in neural cell cultures and imaging techniques.

Qualifications

• 5+ years experience in neuroscience or related field.
• Demonstrated history of exceptional contributions in prior work.

Responsibilities

• Develop methods for characterizing the mechanism of action of ultrasound on neural tissue.
• Design and execute experiments in vitro to assess ultrasound's impact on cellular properties and activity.
• Optimize ultrasound parameters for driving cellular activity and plasticity.
• Translate in-vitro findings to human studies of neuromodulation.

Skills

Neural cell culture methods

Human neural iPSC methods

Calcium imaging

Functional imaging analysis

Education

PhD or Postdoc in neuroscience, molecular/cellular biology, biomedical engineering

Job description

About Nudge

Nudge’s goal is to help the brain work better by creating a generalized product that can precisely stimulate and image the brain, entirely non-invasively. We aim to achieve this by developing cutting-edge ultrasound technology to treat neurological and psychiatric disorders, like addiction, and eventually, creating a mainstream consumer device that can modulate mood, focus, sleep, and more.

To realize those ambitions, we’re growing a scrappy, multidisciplinary, science and engineering team focused on making the best technology possible for interfacing with the whole brain, and a product that has the potential to improve people’s daily lives more than any other.

About the team

The Research Team at Nudge is innovating on multiple frontiers in neuroscience and neurotechnology, and is primarily focused on developing ultrasound-based neuromodulation to treat conditions like depression, chronic pain and addiction as well as enhance the wellbeing of healthy people. We’re also building the first scalable, portable hardware for noninvasive structural ultrasound-based imaging the quality of an MRI. The team is running human trials for neuromodulation and developing algorithms that will enable on-device imaging.

About the role

• Develop methods for characterizing the mechanism of action of ultrasound on neural tissue

• Design and execute experiments in vitro to determine the impact of ultrasound on cellular properties and activity

• Explore optimization of the ultrasound parameter space for driving cellular activity and plasticity

• Translate in-vitro findings to human studies of neuromodulation

About you

• 5+ years experience

• PhD or Postdoc in neuroscience, molecular/cellular biology, biomedical engineering or another science or engineering discipline

• Demonstrated history of exceptional contributions in your prior work experiences

• Experience in one or more of:

  • Neural cell culture methods

  • Human neural iPSC methods

  • Calcium imaging, functional imaging analysis