Research Scientist – Bioanalytics/SPR

Novartis; Cambridge (MA); On-site; USD 81,000 - 151,000; Full time

Benefits offered by this job

401(k) with company match

Health benefits

Job summary

Novartis’s Biologics Research Center in Cambridge, MA seeks a scientifically driven Research Scientist II to advance biologic drug candidates. The role emphasizes antibody characterization by Biacore and other binding methods, with exposure to ELISA and cellular binding assays.

The candidate will develop Biacore methods, analyze data, and present findings within the Bioanalytics team. Collaboration and scientific drive are essential for project success.

Qualifications

• MS or equivalent in biology, chemistry or pharmacology or related field.
• Direct experience in antibody characterization by surface plasmon resonance (Biacore).
• Background in binding characterization using other approaches (Fortebio, Kinexa, flow cytometry, LigandTracer) and ELISA is desirable.
• Excellent organizational and communication skills; able to work in a collaborative team.

Responsibilities

• Provide basic data analysis to interpret experiments across assays.
• Collaborate across teams and train junior associates as needed.
• Present research findings and contribute to lab meetings.
• Communicate effectively to drive project objectives.

Skills

Interpersonal skills

Team collaboration

Biacore SPR experience

Education

MS in biology/chemistry

BS with relevant experience

Tools

Biacore SPR

Job description

Summary

The Biologics Research Center (BRC) discovers and develops biologic therapeutics to treat unmet medical needs in all of Novartis’s disease areas – ranging from oncology, to autoimmune disease, to respiratory diseases and cardiovascular disease. The Bioanalytics group in BRC works with other Novartis scientists to characterize and identify lead molecules as biotherapeutic drugs candidates. We use a range of technologies and approaches to evaluate recombinant protein and cell binding, epitope binning, functional activity to extensively characterize and identify lead molecules.

Summary

The Biologics Research Center (BRC) discovers and develops biologic therapeutics to treat unmet medical needs in all of Novartis’s disease areas – ranging from oncology, to autoimmune disease, to respiratory diseases and cardiovascular disease. The Bioanalytics group in BRC works with other Novartis scientists to characterize and identify lead molecules as biotherapeutic drugs candidates. We use a range of technologies and approaches to evaluate recombinant protein and cell binding, epitope binning, functional activity to extensively characterize and identify lead molecules.

We are looking for a collaborative, inquisitive scientist with an interest and some experience in biologics discovery to join our team.

For this position, some direct experience in antibody characterization by surface plasmon resonance (e.g., Biacore) is required. Additional background in binding characterization using other approaches (e.g., Fortebio, Kinexa, flow cytometry, LigandTracer) and functional assay development (e.g., ELISA) are also relevant and preferred.

About The Role

Internal Job Title: Research Scientist II

Position Location: Cambridge, MA, onsite

The Biologics Research Center (BRC) discovers and develops biologic therapeutics to treat unmet medical needs in all of Novartis’s disease areas – ranging from oncology, to autoimmune disease, to respiratory diseases and cardiovascular disease. The Bioanalytics group in BRC works with other Novartis scientists to characterize and identify lead molecules as biotherapeutic drugs candidates. We use a range of technologies and approaches to evaluate recombinant protein and cell binding, epitope binning, functional activity to extensively characterize and identify lead molecules.

We are looking for a collaborative, inquisitive scientist with an interest and some experience in biologics discovery to join our team.

For this position, some direct experience in antibody characterization by surface plasmon resonance (e.g., Biacore) is required. Additional background in binding characterization using other approaches (e.g., Fortebio, Kinexa, flow cytometry, LigandTracer) and functional assay development (e.g., ELISA) are also relevant and preferred.

As a member of the Bioanalytics team, you must become proficient in developing Biacore methods to address project objectives. Eventually you will independently analyze and interpret Biacore data with the ability to draw own conclusions in alignment with project initiatives and generate own hypotheses to test, troubleshoot and execute the next set of experiments will some input from senior lab members. In addition, you will train and become proficient in mammalian cell culture and cellular binding technologies to characterize antibody molecules binding to cells (e.g. Kinexa, LigandTracer). You will serve on research teams where your data needs to be clearly compiled in a slide deck and effectively presented to the team.

Key Responsibilities

• Provides basic data analysis to interpret own experiments across various learned assays - assesses whether experimental hypothesis was appropriately tested and answered
• Demonstrate awareness of other departmental activities related to assigned projects
• Operate in an interdisciplinary setting requiring a high degree of collaboration within and across teams with training of junior associates as needed
• Present research and participate constructively in working project teams and at lab meetings
  
  

Essential Requirements

• MS or equivalent (e.g., university degree, etc.) in scientific discipline such as biology, chemistry or pharmacology or related, and relevant years of <2 years experience; or BS/apprenticeship (or equivalent) with appropriate and >2 years relevant years of experience in drug discovery, or other related laboratory research. This is not a PhD-level position.
• Direct experience in antibody characterization by surface plasmon resonance (e.g., Biacore).
• Strong interpersonal skills
• Demonstrated Novartis Values & Behaviors
• Distinguished team spirit and scientific drive
• High flexibility, combined with excellent organizational and communication skills
  
  

Desirable Requirements

• Background in binding characterization using other approaches (e.g., Fortebio, Kinexa, flow cytometry, LigandTracer) and functional assay development (e.g., ELISA)
• Experience with mammalian cell culture
  
  

Compensation And Benefits

The salary for this position is expected to range between $81,200 and $150,800 per year. The final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors.

Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards.

US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits. In addition, employees are eligible for a generous time off package including vacation, personal days, holidays and other leaves.

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The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status.

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