Research Scientist, AI for Drug Discovery & Molecule Design

AItoolnavio; San Francisco (CA); On-site; USD 180,000 - 250,000; Full time

Job summary

Chai Discovery in San Francisco seeks research scientists to improve the real-world performance of foundation models for drug discovery. You will design evaluation protocols, plan targeted data generation campaigns, and craft post-training recipes to make models actionable in therapeutic challenges.

You will work closely with pre-training researchers, research engineers, and biology teams to ship results rapidly into real programs and help scientists move medicine forward.

Qualifications

• Published ML research on protein, antibody, or small-molecule modelling.
• Knowledge of protein language, structure prediction, and design models (AlphaFold, RFDiffusion, ProteinMPNN, ESM, etc).
• Strong CS/math/physics background, especially probability, statistics and ML.
• Deep software engineering experience with large codebases.

Responsibilities

• Plan targeted data generation campaigns and design evals to measure model performance.
• Develop post-training recipes to make models useful for real drug discovery problems and ship results quickly.

Skills

Protein ML research

Protein language & design

Quantitative background

Large codebases

Tools

AlphaFold

ESM

ProteinMPNN

Job description

Chai Discovery in San Francisco seeks research scientists to improve the real-world performance of foundation models for drug discovery. You will design evaluation protocols, plan targeted data generation campaigns, and craft post-training recipes to make models actionable in therapeutic challenges.

You will work closely with pre-training researchers, research engineers, and biology teams to ship results rapidly into real programs and help scientists move medicine forward.