Research Scientist - AI-Driven Immunology Lab

Singleton Bio; South San Francisco (CA); In loco; USD 120.000 - 190.000; Tempo pieno

Descrizione del lavoro

Singleton Bio in South San Francisco, CA seeks a hands-on Research Scientist to build lab capabilities, validating virtual tissue model outputs with cell- and tissue-based assays. You will work with genetic and pharmacologic perturbations, expert flow cytometry, and multi-parameter readouts in autoimmune contexts.

The role emphasizes benchwork, data integration, and collaboration with computational teams to advance mechanistic insights and therapeutic targets for immunological diseases.

Competenze

• Ph.D. in cell biology, immunology, biochemistry, pharmacology, or related field with 1–4 years post-doc/industry OR MS/BS with 6+ years industry experience.
• Direct experience in autoimmune and/or chronic inflammatory disease therapeutic areas.
• Aseptic mammalian cell culture experience including primary human cells.

Mansioni

• Translate virtual tissue model outputs into testable in vitro hypotheses.
• Validate targets by genetic perturbation and pharmacologic perturbation with readouts.
• Design and run flow cytometry assays to immunophenotype human immune cells.

Conoscenze

Multicolor flow cytometry

Immune functional assays

Dose–response analysis

Assay design & validation

Data analysis (Python/R)

Formazione

PhD in cell biology/immunology/biochemistry/pharmacology

MS/BS with 6+ years industry experience

Strumenti

FlowJo

multimode plate readers

Luminex/ELISA/MSD/AlphaLISA

qRT-PCR

Descrizione del lavoro

Singleton Bio in South San Francisco, CA seeks a hands-on Research Scientist to build lab capabilities, validating virtual tissue model outputs with cell- and tissue-based assays. You will work with genetic and pharmacologic perturbations, expert flow cytometry, and multi-parameter readouts in autoimmune contexts.

The role emphasizes benchwork, data integration, and collaboration with computational teams to advance mechanistic insights and therapeutic targets for immunological diseases.