Research Fellow-LS-Dr Kun Ling-BMB

Mayo Foundation for Medical Education and Research; Rochester (MN); On-site; USD 67,000 - 79,000; Full time

Benefits offered by this job

Medical plans

Dental and flexible coverage

Vision plan

HSA/FSAs

Competitive retirement

Job summary

Mayo Clinic Rochester invites applications for a Life Sciences Research Fellow in the Translational PKD Center. The role focuses on understanding how primary cilia regulate kidney cyst formation using cultured cells, organoids, and mouse models.

Candidates with strong molecular biology training are encouraged to apply. The position is full-time, exempt, with typical hours Monday–Friday and occasional weekends.

Qualifications

• Must have a Ph.D., M.D., or equivalent doctoral degree in a field deemed relevant by the program.
• Research Fellow is appropriate for individuals who have completed no more than one prior postdoctoral fellowship, at Mayo Clinic or elsewhere.

Responsibilities

• Engage in PKD pathogenesis research using cell lines, organoids, and animal models.
• Apply molecular biology techniques including cloning, mutagenesis, cell culture, transfection, and immunoblotting.
• Collaborate within the Mayo Clinic Translational PKD Center and leverage state-of-the-art facilities.

Education

Ph.D., M.D., or equivalent doctoral degree

Job description

Why Mayo Clinic

Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans– to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.

Benefits Highlights

• Medical:Multiple plan options.
• Dental:Delta Dental or reimbursement account for flexible coverage.
• Vision:Affordable plan with national network.
• Pre-Tax Savings:HSA and FSAs for eligible expenses.
• Retirement: Competitive retirement package to secure your future.

Responsibilities

This position opens for a project focused on comprehending the pathogenesis of polycystic kidney disease, the #1 monogenic human disease leading to kidney failure and death. We integrate cultured cell lines, organoids, and animal models to understand how primary cilia regulate the formation of kidney cysts during development and aging. We welcome individuals who are highly curious to molecular mechanisms underlying human diseases and highly motivated and committed to explorative mechanistic research. Common molecular and cellular techniques are required, including molecular cloning, mutagenesis, cell culture and transfection, and immunoblotting.

Experience on recombinant protein expression and pull-down assays would be beneficial. Candidates familiar with various microscope imaging techniques especially immunofluorescence microscopy are highly encouraged to apply. The project also involves proteomics studies, as well as investigating disease phenotype in established mouse models using MRI imaging and histological analyses.

This lab is affiliated with the Mayo Clinic Translational PKD Center and closely collaborates with its world-renown PKD researchers and physicians. Succeeding candidate will have full access to research tools and the state-of-the-art technical services available at the PKD Center, including patient samples and disease models that can be used for pre-clinical studies if promising drug targets are defined. While we greatly appreciate the independent problem-solving ability that is critical for research, we do recognize the uniqueness of each lab member and encourage teamwork and collaboration, devoting to cultivate a supportive environment to promote personal growth.

A Research Fellow position in Life Sciences (LS) will require knowledge of either clinical-based research or laboratory-based research often obtained from a postdoctoral program.

A Research Fellow at Mayo Clinic is a temporary position intended to provide training and education in research. Individuals will train in the research program of a Mayo Clinic principal investigator. Qualified individuals will demonstrate the potential for research as evidenced by their training and peer-reviewed publications and should become competitive for national research grants. Proof of English proficiency is required for J-1 Short-Term Scholars, Research Scholars, Professors, Specialists, and Student Interns sponsored by Mayo Clinic.

Qualifications

Must have a Ph.D., M.D., or equivalent doctoral degree in a field deemed relevant by the program. Research Fellow is appropriate for individuals who have completed no more than one prior postdoctoral fellowship, at Mayo Clinic or elsewhere.

Exemption Status

Exempt

Compensation Detail

$67,282.95 - $78,711.15 / year; Education, experience and tenure may be considered along with internal equity when job offers are extended.

Benefits Eligible

Yes

Schedule

Full Time

Hours/Pay Period

80

Schedule Details

Monday - Friday 8:00 am - 5:00 pm

Weekend Schedule

Occasional weekends

International Assignment

No

Site Description

Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is.

Equal Opportunity

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the'EOE is the Law'. Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.