Research Associate Position - Lazar laboratory

Upenn; Philadelphia (Philadelphia County); On-site; USD 70,000 - 90,000; Full time

Job summary

The University of Pennsylvania's Perelman School of Medicine invites applications for a Research Associate in the Division of Endocrinology, Diabetes and Metabolism. The appointment is initially for one year with potential renewal based on performance and funding. Candidates must have a Ph.D.

and at least three years of postdoctoral research experience. Responsibilities include studies on thyroid hormone receptor mechanisms, gene transcription analysis, and work with animal models of thyroid

Qualifications

• Must have a Ph.D. degree.
• Minimum of three years of postdoctoral research experience.

Responsibilities

• Conduct experiments to elucidate mechanisms of thyroid hormone receptors in cells and in vivo; develop novel methods of gene transcription and analysis in liver and other tissues.
• Work with animal models of hypothyroidism and hyperthyroidism; utilize molecular biology techniques including ChIP-seq, single cell RNA-seq, ATAC-seq; generate mutant mouse models.
• Collaborate with lab members and contribute to research objectives; pursue an academic career in a supportive environment.

Skills

Team collaboration

Experimental design

Molecular biology techniques

Education

Ph.D. degree

Tools

ChIP-seq

single cell RNA-seq

ATAC-seq

Mutant mice models

Job description

University of Pennsylvania: Perelman School of Medicine: Perelman School of Medicine - Department of Medicine: Perelman School of Medicine - Medicine - Endocrinology, Diabetes and Metabolism

Location

Philadelphia, PA

Open Date

Apr 27, 2026

Deadline

Apr 27, 2028 at 11:59 PM Eastern Time

Description

The Division of Endocrinology, Diabetes and Metabolism in the Department of Medicine at the Perelman School of Medicine at the University of Pennsylvania seeks candidates for a Research Associate position in the Academic Support Staff. This appointment will be initially for one (1) year and continuation during that time period and renewal are based on satisfactory performance and availability of funding (limited to three (3) years). Applicants must have a Ph.D. degree. Position requires a minimum of three years of postdoctoral research experience.

Responsibilities may include experiments related to determining mechanisms underlying the functions of thyroid hormone receptors in cells and in vivo by developing novel methods of gene transcription and analysis in liver and other tissues. Applicant must have experience working with animal models of hypothyroidism and hyperthyroidism, and expertise in molecular biology techniques including ChIP-seq, single cell RNA-seq, ATAC-seq, and generation of mutant mice models. The longer-term goal is understanding mechanisms relating to diabetes, obesity, and their comorbidities including metabolic liver disease.

The successful applicant will have an opportunity to develop a customized training experience in research that allows the individual to attain personal career objectives while developing a career in an academic setting.

The Research Associate will be expected to collaborate with other members of the lab in their research areas and give their contributions.

The University of Pennsylvania is an equal opportunity employer. Candidates are considered for employment without regard to race, color, sex, sexual orientation, religion, creed, national origin (including shared ancestry or ethnic characteristics), citizenship status, age, disability, veteran status or any class protected under applicable federal, state, or local law.