Research Associate-Pharmaceutical Sciences

UT Health Sciences; Memphis (TN); Presencial; USD 51.000 - 59.000; Jornada completa

Descripción de la vacante

UT Health Sciences in Memphis, TN, is seeking a PhD-level scientist to support pre-clinical drug development focused on pharmacokinetics, PK/PD modeling, and LC-MS/MS bioanalysis in animal models.

The role includes mentoring graduate students and postdocs, coordinating experimental plans, and presenting findings at scientific meetings. Strong communication skills and independent work are essential.

Formación

• Ph.D. in pharmacology, pharmaceutical sciences, or related field (transcript required).
• Five years of pharmacokinetic research and LC-MS based analysis of small molecules in biological fluids.

Responsabilidades

• Oversee and perform research work with lab members and provide input on experimental planning.
• Plan, execute, document, and analyze in vitro and in vivo PK studies.
• Perform PK analyses and modeling using PK software.
• Develop and validate LC-MS/MS assays and analyze biological samples.
• Mentor graduate students and junior staff in techniques.
• Ensure compliance and safety in experiments.
• Present data at scientific meetings and maintain thorough documentation.

Conocimientos

Pharmacokinetics

LC-MS/MS

Pharmacometric modeling

Scientific communication

Educación

Ph.D. in pharmacology/pharmaceutical sciences

Herramientas

Phoenix WinNonlin

NONMEM

R

Descripción del empleo

Job Description

Market Range: 11

Hiring Salary: $4,600.33 - $5,250.00/Monthly

THIS IS A GRANT-FUNDED POSITION FUNDED UNTIL JUNE 30, 2029.

JOB SUMMARY/ESSENTIAL JOB FUNCTIONS

Under the direction of an assigned supervisor, this position contributes to the small molecule drug development efforts and is focused on supporting pre-clinical drug development in animal models with specific focus on pharmacokinetic assessments, pharmacokinetic/pharmacodynamic modeling and simulation, application of pharmacometrics techniques and bioanalytical analysis using liquid-chromatography tandem mass spectrometry. Assists with mentoring graduate assistants, junior fellows, and research assistants in proper laboratory procedure and techniques.

Responsibilities

• Works independently and collaboratively with research lab members to oversee and perform research work and provide scientific expertise/input on experimental planning for assigned projects.
• Plans, executes, documents, and analyzes in vitro and in vivo studies in pharmacokinetics and drug metabolism.
• Performs pharmacokinetic analyses and modeling using PK software, including Phoenix WinNonlin, NONMEM, and R.
• Develops and validates LC-MS/MS assays and analyzes biological samples.
• Assists in managing day-to-day lab activities for the assigned lab space.
• Performs basic material and lab equipment management functions, including ordering and stocking supplies.
• Assists in mentoring and training graduate students and junior postdocs in pharmacokinetic and bioanalytical techniques.
• Assists in gaining approval and adhering to compliance requirements for all performed experimentation.
• Presents research data at scientific meetings and conferences.
• Creates and updates thorough documentation of research activities and results, as well as lab-related safety policies; updates them as needed.
• Performs other related duties as assigned.

Qualifications

MINIMUM REQUIREMENTS:

EDUCATION: Ph.D. in pharmacology, pharmaceutical sciences, or related field of study. (TRANSCRIPT REQUIRED)

EXPERIENCE: Five (5) years of experience in pharmacokinetic research and LC-MS based analysis of small molecule drugs and metabolites in biological fluids, preferably related to anti-infective drug development with at least three (3) years as a Postdoctoral Scholar. Experience in maintaining and organizing lab space. (Minimum of five years of experience in animal-based pharmacology research preferred).

Knowledge, Skills, And Abilities

• Ability to work independently in planning, development, standardization, validation, and documentation of LC-MS/MS based assays including sample preparation for quantitation of drugs in biological samples.
• Demonstrated knowledge in handling and utilizing pharmacokinetic animal models.
• Knowledge and proficiency in population pharmacokinetic analyses techniques.
• Ability to communicate efficiently with colleagues from other disciplines and work as a highly motivated self-starter that is creative, result- and milestone-oriented.
• Ability to display high competency and experience in pharmacokinetic data analysis.
• Excellent oral and written communication and presentation skills in English are required.
• Knowledge and proficiency in clinical pharmacology and clinical research would be an advantage.