Research Associate, Molecular and Cell Biology

Chan Zuckerberg Biohub Network; San Francisco (CA); On-site; USD 71,000 - 98,000; Full time

Job summary

A prominent research organization in San Francisco seeks a Research Associate to support molecular and cell biology initiatives, focusing on high-throughput technologies. Candidates should have a B.Sc. in a related field and at least one year of experience in cell biology, tissue culture, and microscopy. The position offers competitive compensation ranging from $71,000 to $98,000 annually, depending on skills and experience.

Qualifications

• At least 1 year of cell biology experience in a research laboratory.
• At least 1 year of tissue culture experience.
• At least 1 year of microscopy experience.
• Enthusiasm for collaboration and open science.

Responsibilities

• Perform cell engineering using CRISPR-Cas9 or recombinase system.
• Execute live-cell imaging experiments for large-scale datasets.
• Contribute to publications through data generation and documentation.

Skills

Cell engineering using CRISPR-Cas9

Molecular biology techniques (PCR, plasmid cloning)

Live-cell and fixed-cell imaging

Data analysis using Python

Strong attention to detail

Excellent communication skills

Education

B.Sc. in Cell Biology, Molecular Biology, or Bioengineering

Job description

Overview

Research Associate, Molecular and Cell Biology – Chan Zuckerberg Biohub Network. The ROLE supports the CELLxSTATE Program, which builds high-throughput, multi-modal cell biology technologies including high-content imaging, genome engineering, and data science. The Intracellular Architecture team at CZ Biohub San Francisco works to map the molecular architecture of human cells and how it changes in disease, using genome engineering, fluorescence microscopy, proteomics, robotics, software, and data science. Our work is open-source and shared with the broader community (as demonstrated by projects such as OpenCell).

Responsibilities

• Perform cell engineering using the CRISPR-Cas9 system or recombinase system.
• Apply basic molecular biology techniques such as PCR, plasmid cloning, and DNA/RNA preparation to support cell engineering and molecular assays.
• Execute live-cell and fixed-cell imaging experiments, with a focus on high-content imaging to generate large-scale, quantitative datasets.
• Manipulate cellular function using chemical and CRISPR-based perturbations.
• Analyze experimental data using Python, ImageJ, and Napari.
• Contribute to publications through data generation, figure preparation, and methods documentation, with authorship opportunities.

Qualifications

• B.Sc. in Cell Biology, Molecular Biology, Bioengineering or a related discipline
• At least 1 year of cell biology experience in an academic or industrial research laboratory setting
• At least 1 year of tissue culture experience
• At least 1 year of microscopy experience
• Strong attention to detail in maintaining lab notebooks
• Passion for research and learning new techniques
• Enthusiasm for collaboration and open science and a team-oriented mindset
• Excellent written and oral communication skills

Compensation and Benefits

• Base pay range for a new hire in San Francisco, CA: $71,000.00 – $98,000.00. Actual placement depends on skills and experience.
• Benefits vary by location and role.

Equal Opportunity

Chan Zuckerberg Biohub Network is an equal opportunity employer. We encourage applications from individuals of all backgrounds and experiences.